Öz
Several medicines, especially antimicrobials, play a role in the etiology of fixed drug eruption (FDE). The clinical manifestation is quite typical for a drug-induced reaction. FDE which developed in an 83-year-old male patient who has been administered colistin due to Acinetobacter pneumonia is presented here since it is very rarely seen. Therefore colistin should also be considered in the differential diagnosis of FDE. J Clin Exp Invest 2013; 4 (3): 374-376
Anahtar Kelimeler
Kaynakça
- Ozkaya E. Fixed drug eruption: state of the art. J Dtsch Dermatol Ges 2008;6:181-188.
- Patel RM, Marfatia YS. Clinical study of cutaneous drug eruptions in 200 patients. Indian J Dermatol Venereol Leprol 2008;74:430.
- Yahav D, Farbman L, Leibovici L, Paul M. Colistin: new lessons on an old antibiotic. Clin Microbiol Infect 2012;18:18-29.
- Shiohara T. Fixed drug eruption: pathogenesis and diagnostic tests. Curr Opin Allergy Clin Immunol 2009;9:316-321.
- Bircher AJ, Scherer K. Delayed cutaneous manifes- tations of drug hypersensitivity. Med Clin North Am 2010;94:711-725.
- Wolff K, Johnson RA, Suurmond D. Fitzpatrick’s color atlas and synopsis of clinical dermatology. New York: McGraw Hill, 2005:556-558.
- Arıcan Ö, Ürün M. A case of tenoxicam induced gener- alized (multifocal) bullous fixed drug eruption. Turkish Journal of Geriatrics 2008;11:200-203.
- Horn TD, Hiatt KM. Cutaneous Toxicities of Drugs. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, ed. Lever’s Histopathology of the Skin. Philadelphia, JB Lippincott Co, 2005:324-345.
- Habif T. Exanthems and Drug Eruptions. In: Clinical Dermatology: A Color Guide to Diagnosis and Thera- py. Philadelphia: Mosby, 2009:541-580.
- Falagas ME, Kasiakou SK. Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. Crit Care 2006;10:27.
Öz
Fiks ilaç erüpsiyonu (FİE) etyolojisinde başta antimikrobiyaller olmak üzere çeşitli ilaçlar rol almaktadır. Klinik görünümü, ilaca bağlı gelişen bir reaksiyon için oldukça tipiktir. Literatürde, kolistine bağlı gelişen fiks ilaç erüpsiyonu olgusu bildirilmemiştir. Acinetobacter pnömonisi nedeniyle kolistin kullanılan 83 yaşındaki bir erkek hastada ortaya çıkan fiks ilaç erüpsiyonu, çok nadir görülmesi açısından sunulmuştur. FİE ayırıcı tanısında kolistinin yer alabileceği akılda tutulmalıdır.
Anahtar Kelimeler
Kaynakça
- Ozkaya E. Fixed drug eruption: state of the art. J Dtsch Dermatol Ges 2008;6:181-188.
- Patel RM, Marfatia YS. Clinical study of cutaneous drug eruptions in 200 patients. Indian J Dermatol Venereol Leprol 2008;74:430.
- Yahav D, Farbman L, Leibovici L, Paul M. Colistin: new lessons on an old antibiotic. Clin Microbiol Infect 2012;18:18-29.
- Shiohara T. Fixed drug eruption: pathogenesis and diagnostic tests. Curr Opin Allergy Clin Immunol 2009;9:316-321.
- Bircher AJ, Scherer K. Delayed cutaneous manifes- tations of drug hypersensitivity. Med Clin North Am 2010;94:711-725.
- Wolff K, Johnson RA, Suurmond D. Fitzpatrick’s color atlas and synopsis of clinical dermatology. New York: McGraw Hill, 2005:556-558.
- Arıcan Ö, Ürün M. A case of tenoxicam induced gener- alized (multifocal) bullous fixed drug eruption. Turkish Journal of Geriatrics 2008;11:200-203.
- Horn TD, Hiatt KM. Cutaneous Toxicities of Drugs. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, ed. Lever’s Histopathology of the Skin. Philadelphia, JB Lippincott Co, 2005:324-345.
- Habif T. Exanthems and Drug Eruptions. In: Clinical Dermatology: A Color Guide to Diagnosis and Thera- py. Philadelphia: Mosby, 2009:541-580.
- Falagas ME, Kasiakou SK. Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. Crit Care 2006;10:27.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Eylül 2013 |
| Yayımlandığı Sayı | Yıl 2013 Cilt: 4 Sayı: 3 |