Current treatment methods in osteoarthritis

Yıl 2012, Cilt: 3 Sayı: 1, 137 - 140, 01.03.2012

Demet Uçar Mehtap Bozkurt

https://doi.org/10.5799/ahinjs.01.2012.01.0132

Cited By: 1

Öz

Osteoarthritis, the most common chronic disease in the joints, resulting destruction. It is the most common cause of pain and loss of function in society. The primary goal of treatment, to educate patients about the course and results of the disease, to prevent the progression of joint damage and alleviate pain, and provide functionality in activities of daily living. To date, several options are defined on the treatment of osteoarthritis. In this review, current non-surgical methods of treatment will be discussed in osteoarthritis.

Anahtar Kelimeler

Osteoarthritis, medical treatment, outcome

Osteoartritte güncel tedavi yöntemleri

Öz

Osteoartrit, eklemlerde en sık rastlanan, destruksiyonla sonuçlanan kronik bir hastalıktır. Eklemlerdeki ağrı ve fonksiyon kaybının toplumdaki en sık nedenidir. Tedavide öncelikli hedef, hastalığın seyri ve sonuçları konusunda hastayı eğitmek, ağrıyı hafifletip günlük yaşam aktivitelerindeki fonksiyonelliği sağlamak ve eklem hasarının ilerlemesini önlemektir. Bugüne kadar osteoartrit tedavisi ile ilgili birçok farmakolojik, nonfarmakolojik ve cerrahi tedavi seçenekleri tanımlanmıştır. Bu derlemede cerrahi dışı güncel tedavi yöntemleri tartışılacaktır.

Anahtar Kelimeler

Osteoartrit, tıbbi tedavi, sonuçlar

Kaynakça

• Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K et al. Development of criteria for the classifi- cation and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and therapeutic criteria committee of the American Rheumatism Asso- ciation. Arthritis Rheum 1986; 29(8):1039-49.
• Gür A, Nas K, Çevik R, Erdoğan F, Denli A. The quality of life status of patients with rheumatoid arthritis and osteoarthritis. Dicle Tıp Dergisi 2000; 27(1):15-9.
• Berenbaum F. New horizons and perspectives in the treatment of osteoarthritis. Arthritis Res Ther 2008; 10(2):25-30.
• Zhang W, Nuki G, Moskowitz RW, et al. OARSI rec- ommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009. 2010; 18(4):476-99.
• Hernandez-Molina G, Reichenbach S, Zhang B, Laval- ley M, Felson DT. Effect of therapeutic exercise for hip osteoarthritis pain: results of a meta-analysis. Arthritis Care Res 2008; 59(9): 1218-21.
• Jamtvedt G, Dahm KT, Christie A, et al. Physical ther- apy interventions for patients with osteoarthritis of the knee: an overview of systematic reviews. Phys Ther 2008; 88(1):123–36.
• Roddy E, Zhang W, Doherty M. Aerobic walking or strengthening exercise for osteoarthritis of the knee? A systematic review. Ann Rheum Dis 2005; 64(4):544- 8.
• Bartels EM, Lund H, Hagen KB, Dagfinrud H, Chris- tensen R, Danneskiold-Samsİe B. Aquatic exercise for the treatment ofknee and hip osteoarthritis. Co- chrane Database Sys Rev 2007 Oct17; (4):CD005523
• Towheed TE, Maxwell L, Judd MG, Catton M, Ho- chberg MC, Wells G. Acetaminophen for osteoar- thritis. Cochrane Database Syst Rev 2006 Jan25; (1):CD004257.
• Bjordal JM, Klovning A, Ljunggren AE, Slordal L. Short-term efficacy of pharmacotherapeutic interven- tions in osteoarthritic knee pain: a meta-analysis of randomised placebocontrolled trials. Eur J Pain 2007; 11(2):125–38.
• Chan FK, Wong VW, Suen BY, et al. Combination of a cyclo-oxygenase-2 inhibitor and a proton pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. Lancet 2007; 369(9573):1621-6.
• Zhang W, Moskowitz RW, Nuki G, et al. OARSI rec- ommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treat- ment guidelines and systematic review of current research evidence. Osteoarthritis Cartilage 2007; 15(9):981-1000.
• Zhang W, Moskowitz RW, Nuki G, et al. OARSI rec- ommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage 2008; 16(2):137-62.
• Furlan AD, Sandoval JA, Mailis-Gagnon A, Tunks E. Opioids for chronic noncancer pain: a meta-anal- ysis of effectiveness and side effects. CMAJ 2006; 174(11):1589-94.
• Bellamy N, Campbell J, Robinson V, Gee T, Bourne R, Wells G. Intraarticular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst Rev 2006 Apr19; (2):CD005328.
• Bannuru RR, Natov NS. Therapeutic trajectory of hy- aluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta- analysis. Arthritis Care Res 2009; (61):1704–11.
• Rozendaal RM, Koes BW, van Osch GJ, et al. Effect of glucosamine sulfate on hip osteoarthritis: a ran- domized trial. Ann Intern Med 2008; 148(4):268-77.
• Reichenbach S, Sterchi R, Scherer M, et al. Meta- analysis: chondroitin for osteoarthritis of the knee or hip. Ann Intern Med 2007; 146(8):580-90.
• Kahan A, Uebelhart D, De Vathaire F, Delmas PD, Reginster JY. Long-term effects of chondroitins 4 and 6 sulfate on knee osteoarthritis: the study on osteo- arthritis progression prevention, a two-year, random- ized, double-blind, placebocontrolled trial. Arthritis Rheum 2009; 60(2):524-33.
• Pavelka K, Trc T, Karpas K, et al. The efficacy and safety of diacerein in the treatment of painful osteo- arthritis of the knee: a randomized, multicenter, dou- ble-blind, placebo-controlled study with primary end points at two months after the end of a three-month treatment period. Arthritis Rheum 2007; 56(12):4055- 64.
• Carbone LD, Nevitt MC, Wildy K, et al. The relation- ship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis.Arthritis Rheum 2004; 50(11):3516–25.
• Garnero P, Aronstein WS, Cohen SB, et al. Rela- tionships between biochemical markers of bone and cartilage degradation with radiological progression in patients with knee osteoarthritis receiving risedronate: the knee osteoarthritis structural arthritis randomized clinical trial. Osteoarthritis Cartilage 2008; 16(6):660–6.
• Alexandersen P, Karsdal MA, Qvist P, Reginster JY, Christiansen C. Strontium ranelate reduces the uri- nary level of cartilage degradation biomarker CTX-II inpostmenopausal women. Bone 2007;40(1): 218-22.
• Ravn P, Warming L, Christgau S, Christiansen C. The effect on cartilage of different forms of application of postmenopausal estrogen therapy: comparison of oral and transdermal therapy. Bone 2004;35(5):1216–21.
• Christgau S, Tanko LB, Cloos PA, et al. Suppression of elevated cartilage turnover in postmenopausal women and in ovariectomized rats by estrogen and a selective estrogen-receptor modulator (SERM). Menopause 2004;11(5):508–18.
• Manicourt DH, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP. Oral salmon calcitonin reduces Le- quesne’s algofunctional index scores and decreas- es urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum 2006;54(10):3205–11.
• Brouwer RW, Jakma TS, Verhagen AP, Verhaar JA, Bierma-Zeinstra SM. Braces and orthoses for treating osteoarthritis of the knee. Cochrane Database Syst Rev 2005 Jan25;(1):CD004020.