Deep venous thrombosis is mostly associated with an underlying risk factor such as venous catheter, infectious diseases, hereditary thrombophilia and metabolic diseases. Cancer is one of the most common primary disorders in pediatric venous thrombosis, accounting for one-fifth of children with thrombotic events. Here we report a 13-year-old female patient who is diagnosed as deep vein thrombosis due to acute myeloid leukemia.
Van Ommen CH, Heijboer H, Buller HR, Hirasing RA, Heijmans HS, Peters M. Venous thromboembolism in childhood: a prospective two-year registry in The Nether- lands. J Pediatr 2001;139: 676-681.
Revel-Vilk S, Massicotte P. Thromboembolic diseases of childhood. Blood Reviews 2003;17:1-6.
Kuhle S, Massicotte P, Chan A, et al. Systemic thromboem- bolism in children. Thromb Haemost 2004;92:722-728.
Bajzar L, Chan AK, Massicotte MP, et al. Thrombosis in children with malignancy. Curr Opin Pediatr 2006;18:1-9.
Gorczyca W. Flow cytometry immunophenotypic character- istics of monocytic population in acute monocytic leuke- mia (AML-M5), acute myelomonocytic leukemia (AML- M4), and chronic myelomonocytic leukemia (CMML). Methods Cell Biol 2004;75:665–677.
Andrew M, David M, Adams M, et al. Venous thromboem- bolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood 1994;83:1251–1257.
Parasuraman S, Goldhaber SZ. Venous thromboembolism in children. Circulation 2006;113:12-16.
Göttl NU, Kenet G, Mitchell LG. Thrombosis in childhood acute lymphoblastic leukaemia: epidemiology, etiology, diagnosis, prevention and treatment. Best Prac- tice&Research Clinical Haematology 2009;22:103-114.
Ku GH, White RH, Chew HK, et al. Venous thromboem- bolism in patients with acute leukemia: incidence, risk fac- tors, and effect on survival. Blood 2009;113:3911-3917.
Sutherland DE, Weitz IC, Liebman HA. Thromboembolic complications of cancer: epidemiology, pathogenesis, di- agnosis and treatment. Am J Hematol 2003;72:43-52.
Celkan T, Apak H, Özkan A, et al. Hastanede yatan çocuk- larda saptanan tromboz etiyolojisi. Türk Pediatri Arşivi 2004;39:65-67. .
Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu
Çocuklarda görülen venöz tromboz çoğunlukla kateterizasyon, enfeksiyöz hastalıklar, kalıtsal trombofili ve metabolik hastalıklar gibi altta yatan bir risk faktörü ile ilişkilidir. Kanser çocukluk çağında görülen primer venöz trombozların önemli bir nedenidir ve çocukluk çağı venöz tromboz olgularının beşte birinden sorumludur. Bu yazıda ilk başvuru bulgusu derin ven trombozu olan ve takibinde akut myeloid lösemi (AML) tanısı konulan 13 yaşında kız hasta sunulmuştur.
Van Ommen CH, Heijboer H, Buller HR, Hirasing RA, Heijmans HS, Peters M. Venous thromboembolism in childhood: a prospective two-year registry in The Nether- lands. J Pediatr 2001;139: 676-681.
Revel-Vilk S, Massicotte P. Thromboembolic diseases of childhood. Blood Reviews 2003;17:1-6.
Kuhle S, Massicotte P, Chan A, et al. Systemic thromboem- bolism in children. Thromb Haemost 2004;92:722-728.
Bajzar L, Chan AK, Massicotte MP, et al. Thrombosis in children with malignancy. Curr Opin Pediatr 2006;18:1-9.
Gorczyca W. Flow cytometry immunophenotypic character- istics of monocytic population in acute monocytic leuke- mia (AML-M5), acute myelomonocytic leukemia (AML- M4), and chronic myelomonocytic leukemia (CMML). Methods Cell Biol 2004;75:665–677.
Andrew M, David M, Adams M, et al. Venous thromboem- bolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood 1994;83:1251–1257.
Parasuraman S, Goldhaber SZ. Venous thromboembolism in children. Circulation 2006;113:12-16.
Göttl NU, Kenet G, Mitchell LG. Thrombosis in childhood acute lymphoblastic leukaemia: epidemiology, etiology, diagnosis, prevention and treatment. Best Prac- tice&Research Clinical Haematology 2009;22:103-114.
Ku GH, White RH, Chew HK, et al. Venous thromboem- bolism in patients with acute leukemia: incidence, risk fac- tors, and effect on survival. Blood 2009;113:3911-3917.
Sutherland DE, Weitz IC, Liebman HA. Thromboembolic complications of cancer: epidemiology, pathogenesis, di- agnosis and treatment. Am J Hematol 2003;72:43-52.
Celkan T, Apak H, Özkan A, et al. Hastanede yatan çocuk- larda saptanan tromboz etiyolojisi. Türk Pediatri Arşivi 2004;39:65-67. .
Çalık, M., Pişkin, İ. E., Üstündağ, G., Kardeş, H. (2011). Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu. Journal of Clinical and Experimental Investigations, 2(1), 114-117. https://doi.org/10.5799/ahinjs.01.2011.01.0223
AMA
Çalık M, Pişkin İE, Üstündağ G, Kardeş H. Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu. J Clin Exp Invest. Mart 2011;2(1):114-117. doi:10.5799/ahinjs.01.2011.01.0223
Chicago
Çalık, Mustafa, İbrahim Etem Pişkin, Gonca Üstündağ, ve Hakan Kardeş. “Derin Ven Trombozu Ile başvuran Bir Akut Miyeloid lösemi Olgusu”. Journal of Clinical and Experimental Investigations 2, sy. 1 (Mart 2011): 114-17. https://doi.org/10.5799/ahinjs.01.2011.01.0223.
EndNote
Çalık M, Pişkin İE, Üstündağ G, Kardeş H (01 Mart 2011) Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu. Journal of Clinical and Experimental Investigations 2 1 114–117.
IEEE
M. Çalık, İ. E. Pişkin, G. Üstündağ, ve H. Kardeş, “Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu”, J Clin Exp Invest, c. 2, sy. 1, ss. 114–117, 2011, doi: 10.5799/ahinjs.01.2011.01.0223.
ISNAD
Çalık, Mustafa vd. “Derin Ven Trombozu Ile başvuran Bir Akut Miyeloid lösemi Olgusu”. Journal of Clinical and Experimental Investigations 2/1 (Mart 2011), 114-117. https://doi.org/10.5799/ahinjs.01.2011.01.0223.
JAMA
Çalık M, Pişkin İE, Üstündağ G, Kardeş H. Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu. J Clin Exp Invest. 2011;2:114–117.
MLA
Çalık, Mustafa vd. “Derin Ven Trombozu Ile başvuran Bir Akut Miyeloid lösemi Olgusu”. Journal of Clinical and Experimental Investigations, c. 2, sy. 1, 2011, ss. 114-7, doi:10.5799/ahinjs.01.2011.01.0223.
Vancouver
Çalık M, Pişkin İE, Üstündağ G, Kardeş H. Derin ven trombozu ile başvuran bir akut miyeloid lösemi olgusu. J Clin Exp Invest. 2011;2(1):114-7.