Öz
Objective: Evaluation of long-term results of primary trabeculectomy operationMethods: The cases that are followed up with diagnosis of glaucoma in Okmeydanı Training and Research Hospital Eye Clinic between January 2000 and December 2001 were evaluated retrospectively. All of the cases, despite maximum therapy, have high intraocular pressure (IOP), undergone primary trabeculectomy operation, are followed at least 6 months and regularly followed through 10 years were included in this study. IOP with or without medical treatment 18mmg or less than 18 mmHg accepted as successful. IOL pressure measured with applanation tonometry. Results: 89 eyes of 70 cases were included in this study. The cases included in the study, 42 male (60%), and 28 (40%) were female. The mean age was 63.65±12.18 years. Preoperative intraocular pressure determined as 30.36 ± 3.2 mmHg. In the follow up examination mean intra ocular pressure was 15.31 ± 1.2 mmHg at 1st month, 15.47± 1.1mmHg at 3rd month, 15.02±1.8 mmHg at 6thmonth, 15.34± 2.1 mmHg at 1st year, 15.82 ± 2.1mmHg at 2nd year, 17.06 ± 2.3mmHg at 5th year and 18.02 ± 2.2 mmHg at 10th year. Statistical analysis of these data showed significant decreased of intra ocular pressure in the post operative period in compare to the preoperative period, 1st month, 3rd month, 6th month, 1st year, 2nd year, 5th year an 10th year (p < 0.01). The follow-up period in the study was 91.10 ± 40.15 months (6-120 months).Conclusion: Primary trabeculectomy can be considered as an alternative treatment procedure especially in patients who does not use drugs regularly and unable to attend regular medical examination. J Clin Exp Invest 2015; 6 (3): 263-268
Anahtar Kelimeler
Kaynakça
- Russo V, Barone A, Cosma A, et al. Selective laser trabeculoplasty versus argon laser trabeculoplasty in patients with uncontrolled open-angle glaucoma. Eur J Ophthalmol 2009;19:429-434.
- Grehn F, Hollo G, Lachtar Y, rt al. Glokom İçin Terminoloji ve Rehber, Traverso CE, 2. Basım, Savona, İtalya, Editrice Dogma S.r.l 2004;1-4.
- Sugar AS. Experimental trabeculectomy in glaucoma. Am J Ophthalmol 1961;51:623-627.
- Cairns JE: Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol 1968; 66:673-679.
- Landers J, Martin K, Sarkies N, et al. A twenty-year follow-upstudy of trabeculectomy: risk factors and outcomes. Ophthalmology 2012;119:694-702.
- Robinson D, Lertsumitkul S, Billson FA, Robinson LP. Long-term intraocular pressure control by trabeculectomy: A ten-year life table, Aust N Z J Ophthalmol 1993;21:79–85.
- Mills KB. Trabeculectomy: A retrospective long-term follow-up of 444 cases. BrJ Ophthalmol 1981;65:790-795.
- Turaçlı ME, Özkan AÜ, Trabekülektomi, Ankara Üniversitesi TF Göz Kliniği Yıllığı, Ankara, 1976:127.
- Popovic V, Sjöstrand J, Long-term outcome following trabeculectomy: I. Retrospective analysis of intraocular pressure regulation and cataract formation, Acta Ophthalmol (Copenh) 1991;69:299-304.
- Cheung JC, Wright MM, Murali S, Pederson JE, Intermediate-
- term outcome of variable dose mitomycin-C filtering surgery, Ophthalmology 1997;104:143-149.
- Yalvaç IS, Yüzer H, Akgün Ü, et al. İlerleyen zaman içinde trabkülektominin etkinliği, T Oft Gaz 1998;28:318-321.
- Katz LJ, Spaeth GL, Cantor LB, et al. Reversible optic disk cupping and visual field improvement in adults with glaucoma, Am J Ophthalmol1989;15;107:485-492.
- Akafo SK, Goulstine DB, Rosenthal AR, Long-term posttrabeculectomy intraocular pressures. Acta Ophthalmol (Copenh) 1992;70:312-16.
- Molteno AC, Bosma NJ, Kittelson JM. Otago glaucoma surgery outcome study: long-term results of trabeculectomy--1976 to 1995. Ophthalmology 1999;106:1742-1750.
- Yıldırım E, Bilge AH, İlker S., Improvement of visual field following trabeculectomy for open angle glaucoma. Eye 1990;4:103-106.
- Richter CU, Shingleton BJ, Bellows AR, et al. The development of encapsulated filtering blebs. Ophthalmology 1988;95:1163-1168.
Öz
Amaç: Primer trabekülektomi ameliyatının uzun dönem sonuçlarının değerlendirilmesi
Yöntemler: Okmeydanı Eğitim Araştırma Hastanesi Göz Kliniğinde Ocak 2000 – Aralık 2001 tarihleri arasında glokom tanısı ile izlenen, geçmişinde maksimal tedaviye rağmen yüksek göz içi basıncı (GİB) nedeniyle primer trabekülektomi öyküsü olan olgular retrospektif olarak incelendi. Postoperatif dönemde en az 6 ay boyunca takip edilmiş olup, 10 yıl boyunca düzenli takiplere gelen hastalarda çalışmaya dahil edildi. GİB ilaçlı veya ilaçsız 18 mmHg ve altı olgular başarılı olarak kabul edildi. GİB aplanasyon tonometrisi ile ölçüldü.
Bulgular: Bu çalışmaya 70 olgunun 89 gözü dahil edildi. Çalışmaya dahil edilen olguları 42’si erkek (%60), 28’i kadındı (%40). Hastaların ortalama yaşı63,65±12,18 yıl idi. Preoperatif ortalama göz içi basıncı 30,36 ± 3,2 mmHg olarak ölçüldü. Olguların kontrol muayenelerinde ortalama GİB değeri 1.ayda 15,31 ± 1,2 mmHg, 3.Ay 15,47± 1,1mmHg, 6,ay 15,02±1,8mmHg,1. yıl 15,34± 2,1 mmHg, 2.yıl 15,82 ± 2,1 mmHg, 5.yıl 17,06 ± 2,3 mmHg ve 10. yıl 18,02 ± 2,2 mmHg olarak ölçüldü. Bu verilerin istatistiki analizinde postoperatif 1.ay, 3.ay, 6.ay, 1.yıl, 2.yıl, 5.yıl ve 10.yıldapreoperatif döneme göre göz içi basıncında anlamlı bir düşüş olduğu tespit edildi. (p< 0.01) Çalışmaya alınan tüm olguların takip süresi 91,10 ± 40,15 aydı (6 ay – 120 ay).
Sonuç: Primer trabekülektomi özellikle uyumsuz ilaç kullanımı olan hastalarda ve düzenli tıbbi muayeneye gelemeyecek hastalarda alternatif olarak düşünülmesi gereken bir tedavi prosedürüdür.
Anahtar kelimeler: Glokom, göz içi basıncı, trabekülektomi
Anahtar Kelimeler
Kaynakça
- Russo V, Barone A, Cosma A, et al. Selective laser trabeculoplasty versus argon laser trabeculoplasty in patients with uncontrolled open-angle glaucoma. Eur J Ophthalmol 2009;19:429-434.
- Grehn F, Hollo G, Lachtar Y, rt al. Glokom İçin Terminoloji ve Rehber, Traverso CE, 2. Basım, Savona, İtalya, Editrice Dogma S.r.l 2004;1-4.
- Sugar AS. Experimental trabeculectomy in glaucoma. Am J Ophthalmol 1961;51:623-627.
- Cairns JE: Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol 1968; 66:673-679.
- Landers J, Martin K, Sarkies N, et al. A twenty-year follow-upstudy of trabeculectomy: risk factors and outcomes. Ophthalmology 2012;119:694-702.
- Robinson D, Lertsumitkul S, Billson FA, Robinson LP. Long-term intraocular pressure control by trabeculectomy: A ten-year life table, Aust N Z J Ophthalmol 1993;21:79–85.
- Mills KB. Trabeculectomy: A retrospective long-term follow-up of 444 cases. BrJ Ophthalmol 1981;65:790-795.
- Turaçlı ME, Özkan AÜ, Trabekülektomi, Ankara Üniversitesi TF Göz Kliniği Yıllığı, Ankara, 1976:127.
- Popovic V, Sjöstrand J, Long-term outcome following trabeculectomy: I. Retrospective analysis of intraocular pressure regulation and cataract formation, Acta Ophthalmol (Copenh) 1991;69:299-304.
- Cheung JC, Wright MM, Murali S, Pederson JE, Intermediate-
- term outcome of variable dose mitomycin-C filtering surgery, Ophthalmology 1997;104:143-149.
- Yalvaç IS, Yüzer H, Akgün Ü, et al. İlerleyen zaman içinde trabkülektominin etkinliği, T Oft Gaz 1998;28:318-321.
- Katz LJ, Spaeth GL, Cantor LB, et al. Reversible optic disk cupping and visual field improvement in adults with glaucoma, Am J Ophthalmol1989;15;107:485-492.
- Akafo SK, Goulstine DB, Rosenthal AR, Long-term posttrabeculectomy intraocular pressures. Acta Ophthalmol (Copenh) 1992;70:312-16.
- Molteno AC, Bosma NJ, Kittelson JM. Otago glaucoma surgery outcome study: long-term results of trabeculectomy--1976 to 1995. Ophthalmology 1999;106:1742-1750.
- Yıldırım E, Bilge AH, İlker S., Improvement of visual field following trabeculectomy for open angle glaucoma. Eye 1990;4:103-106.
- Richter CU, Shingleton BJ, Bellows AR, et al. The development of encapsulated filtering blebs. Ophthalmology 1988;95:1163-1168.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Araştırma Yazısı |
| Yazarlar | |
| Yayımlanma Tarihi | 25 Ekim 2015 |
| Yayımlandığı Sayı | Yıl 2015 Cilt: 6 Sayı: 3 |