Klinik Araştırma
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Periferik Vertigolu Yaşlı Hastalarda Kan Enflamatuar Parametrelerinin Değerlendirilmesi

Yıl 2021, Cilt 11, Sayı 6, 822 - 826, 20.11.2021
https://doi.org/10.16899/jcm.976130

Öz

 Amaç: Bu çalışmanın amacı, yaşlı hastalarda enfeksiyona bağlı periferik vertigo ile inflamatuar parametreler, beyaz kan hücresi, nötrofil lenfosit oranı, platelet lenfosit oranı ve C-reactive protein arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntem: Çalışmamızda periferik vertigo şikayeti olan 122 hasta geriye dönük olarak değerlendirildi. Cinsiyetleri, yaşları, başvuru şekilleri, acil servisten taburculuk ve yatışları, hastaneye başvuru süreleri, şikayetleri ve fizik muayene bulgu oranları incelendi.
Bulgular: Ortalama yaş 73,4 yıldı. 115 hasta (%94,3) acil serviste izlem sonrası taburcu edilirken, 7 hasta (%5,7) hastaneye yatırıldı. Şikayetler sırasıyla %75,4 baş dönmesi, %18 bulantı-kusma ve %6,4 baş ağrısı idi. platelet, nötrofil, lenfosit, nötrofil lenfosit oranı ve platelet lenfosit oranı değerlerinde istatistiksel olarak anlamlı fark yoktu.
Sonuç: Çalışmamızda hastalarda beyaz kan hücresi ve C-reactive protein değerleri referans değerlerine göre daha yüksek bulundu. Çalışmamızın sonuçları, periferik vertigolu yaşlı hastaların patogenezinde inflamatuar nedenlerin, tanıda aktif olarak kullanılabileceğini göstermiştir. 

Kaynakça

  • 1. Tusa RJ. Bedside assessment of the dizzy patient. Neurol Clin 2005;23:655-673. https://doi.org/10.1016/j.ncl.2005.03.001
  • 2. Kablan A, Karaman S, Başol N. Cost of neuroimaging of patients with vertigo in emergency department. J Contemp Med 2019;9:315-320. https://doi.org/10.16899/jcm.684344
  • 3. Strupp M, Brandt T. Diagnosis and treatment of vertigo and dizziness. Dtsch Arztebl Int 2008;105:173-180. https://doi.org/10.3238/arztebl.2008.0173
  • 4. Labuguen RH. Initial evaluation of vertigo. Am Fam Physician 2006;73:244-251.
  • 5. Hanley K, O’Dowd T. Symptoms of vertigo in general practice: a prospective study of diagnosis. Br J Gen Pract 2002;52:809-812.
  • 6. Greco A, Macri GF, Gallo A, et al. Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo? J Immunol Res 2014;2014:8. https://doi.org/10.1155/2014/459048
  • 7. Chung JH, Lim J, Jeong JH, Kim KR, Park CW, Lee SH. The significance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in vestibular neuritis. Laryngoscope 2015;125:257-261. https://doi.org/10.1002/lary.25204
  • 8. Avcı D. Can mean platelet volume be used as a thrombosis marker in subjective tinnitus? Erciyes Med J 2020;42:157-162. https://doi.org/10.14744/etd.2019.57355
  • 9. Seo YJ, Jeong JH, Choi JY, Moon IS. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Dis Markers 2014;2014:6. https://doi.org/10.1155/2014/702807
  • 10. Kovacs E, Wang X, Grill E. Economic burden of vertigo: a systematic review. Health Econ Rev 2019;9:37. https://doi.org/10.1186/s13561-019-0258-2
  • 11. Tekeşin A, Tunç A. Inflammatory biomarkers in benign paroxysmal positional vertigo: a Turkey case-control study. Ideggyogy Sz 2018;71:411-416. https://doi.org/10.18071/isz.71.0411
  • 12. Bas FY, Tola EN, Sak S, Cankaya BA. The role of complete blood inflammation markers in the prediction of spontaneous abortion. Pak J Med Sci 2018;34:1381-1385. https://doi.org/10.12669/pjms.346.15939
  • 13. Fattori B, Nacci A, Ghilardi PL, Bruschini L, Matteucci F, Ursino F. Acute peripheral vertigo: involvement of the hemostatic system. The Int Tinnitus J. 2003;9:2:124-129. https://pubmed.ncbi.nlm.nih.gov/15106288/
  • 14. Akinci E, Aygencel G, Keles A, Demircan A, Bildik F. Role of C-reactive protein, D-dimer, and fibrinogen levels in the differential diagnosis of central and peripheral vertigo. Adv Therapy 2007;24:1068-1077. https://doi.org/10.1007/BF02877713
  • 15. Sahın C, Varım C, Uyanık M, Acar B, Acar T, Nalbant A. Use of neutrophils to lymphocytes ratio as an ınflammation marker ın patients with chronic tonsillitis. Georgian medical news, New York: 2016;256-257:52-57.
  • 16. Shushan S, Shemesh S, Ungar OJ, et al. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio among patients with vestibular neuritis. ORL 2019;81:304-308. https://doi.org/10.1159/000502152
  • 17. Ozbay I, Kahraman C, Balikci HH, et al. Neutrophil-to-lymphocyte ratio in patients with peripheral vertigo: a prospective controlled clinical study. Am J Otolaryngol 2014;35:699-702. https://doi.org/10.1016/j.amjoto.2014.08.004
  • 18. Temirbekov D, Sakallı E. Effects of peripheral vertigo on inflammatory and immunologic laboratory markers. Ear Nose Throat J 2020;99:470-474. https://doi.org/10.1177/0145561320920149
  • 19. Milionis HJ, Mittari V, Exarchakos G, Kalaitzidis R, Skevas AT, Elisaf MS. Lipoprotein (a) and acute-phase response in patients with vestibular neuronitis. Eur J Clin Invest 2003;33:1045-1050. https://doi.org/10.1111/j.1365-2362.2003.01275.x
  • 20. Yardley L. Contribution of symptoms and beliefs to handicap in people with vertigo: a longitudinal study. Br J Clin Psychol 1994;33:101-113. https://doi.org/10.1111/j.2044-8260.1994.tb01100.x
  • 21. Dağkıran M, Sürmelioğlu Ö, Özlem A. Diagnosis and treatment approach in benign paroxysmal positional vertigo. Archiv Med Rev J 2015;24:555-564. https://doi.org/10.17827/aktd.66259

Assessment of Blood Inflamatory Parameters in Elderly Patients With Peripheral Vertigo

Yıl 2021, Cilt 11, Sayı 6, 822 - 826, 20.11.2021
https://doi.org/10.16899/jcm.976130

Öz

Aim: The aim of this study is to evaluate the relationship between infection-induced PV and inflammatory parameters levels, WBC, NLR, PLR and CRP in elderly patients. Material and Method: In our study, 122 patients with peripheral vertigo complaints were retrospectively evaluated. Their gender, age, the type of admission, emergency room discharge and hospitalization, hospital admission time, complaints, and physical examination findings rates were examined. Results: The mean age was 73.4 years.. 115 patients (94.3%) were discharged after follow-up in the emergency department, while 7 patients (5.7%) were hospitalized. Complaints were 75.4% dizziness, 18% nausea-vomiting and 6.4% headache, respectively. There was no statistically significant difference in PLT, NEU, LYM, NEU / LYM and PLT / LYM values. Conclusion: In our study, WBC and CRP were significantly higher in patients. The results of our study showed that it can be used actively in the diagnosis of inflammatory causes in the pathogenesis of elderly patients with peripheral vertigo.

Kaynakça

  • 1. Tusa RJ. Bedside assessment of the dizzy patient. Neurol Clin 2005;23:655-673. https://doi.org/10.1016/j.ncl.2005.03.001
  • 2. Kablan A, Karaman S, Başol N. Cost of neuroimaging of patients with vertigo in emergency department. J Contemp Med 2019;9:315-320. https://doi.org/10.16899/jcm.684344
  • 3. Strupp M, Brandt T. Diagnosis and treatment of vertigo and dizziness. Dtsch Arztebl Int 2008;105:173-180. https://doi.org/10.3238/arztebl.2008.0173
  • 4. Labuguen RH. Initial evaluation of vertigo. Am Fam Physician 2006;73:244-251.
  • 5. Hanley K, O’Dowd T. Symptoms of vertigo in general practice: a prospective study of diagnosis. Br J Gen Pract 2002;52:809-812.
  • 6. Greco A, Macri GF, Gallo A, et al. Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo? J Immunol Res 2014;2014:8. https://doi.org/10.1155/2014/459048
  • 7. Chung JH, Lim J, Jeong JH, Kim KR, Park CW, Lee SH. The significance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in vestibular neuritis. Laryngoscope 2015;125:257-261. https://doi.org/10.1002/lary.25204
  • 8. Avcı D. Can mean platelet volume be used as a thrombosis marker in subjective tinnitus? Erciyes Med J 2020;42:157-162. https://doi.org/10.14744/etd.2019.57355
  • 9. Seo YJ, Jeong JH, Choi JY, Moon IS. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Dis Markers 2014;2014:6. https://doi.org/10.1155/2014/702807
  • 10. Kovacs E, Wang X, Grill E. Economic burden of vertigo: a systematic review. Health Econ Rev 2019;9:37. https://doi.org/10.1186/s13561-019-0258-2
  • 11. Tekeşin A, Tunç A. Inflammatory biomarkers in benign paroxysmal positional vertigo: a Turkey case-control study. Ideggyogy Sz 2018;71:411-416. https://doi.org/10.18071/isz.71.0411
  • 12. Bas FY, Tola EN, Sak S, Cankaya BA. The role of complete blood inflammation markers in the prediction of spontaneous abortion. Pak J Med Sci 2018;34:1381-1385. https://doi.org/10.12669/pjms.346.15939
  • 13. Fattori B, Nacci A, Ghilardi PL, Bruschini L, Matteucci F, Ursino F. Acute peripheral vertigo: involvement of the hemostatic system. The Int Tinnitus J. 2003;9:2:124-129. https://pubmed.ncbi.nlm.nih.gov/15106288/
  • 14. Akinci E, Aygencel G, Keles A, Demircan A, Bildik F. Role of C-reactive protein, D-dimer, and fibrinogen levels in the differential diagnosis of central and peripheral vertigo. Adv Therapy 2007;24:1068-1077. https://doi.org/10.1007/BF02877713
  • 15. Sahın C, Varım C, Uyanık M, Acar B, Acar T, Nalbant A. Use of neutrophils to lymphocytes ratio as an ınflammation marker ın patients with chronic tonsillitis. Georgian medical news, New York: 2016;256-257:52-57.
  • 16. Shushan S, Shemesh S, Ungar OJ, et al. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio among patients with vestibular neuritis. ORL 2019;81:304-308. https://doi.org/10.1159/000502152
  • 17. Ozbay I, Kahraman C, Balikci HH, et al. Neutrophil-to-lymphocyte ratio in patients with peripheral vertigo: a prospective controlled clinical study. Am J Otolaryngol 2014;35:699-702. https://doi.org/10.1016/j.amjoto.2014.08.004
  • 18. Temirbekov D, Sakallı E. Effects of peripheral vertigo on inflammatory and immunologic laboratory markers. Ear Nose Throat J 2020;99:470-474. https://doi.org/10.1177/0145561320920149
  • 19. Milionis HJ, Mittari V, Exarchakos G, Kalaitzidis R, Skevas AT, Elisaf MS. Lipoprotein (a) and acute-phase response in patients with vestibular neuronitis. Eur J Clin Invest 2003;33:1045-1050. https://doi.org/10.1111/j.1365-2362.2003.01275.x
  • 20. Yardley L. Contribution of symptoms and beliefs to handicap in people with vertigo: a longitudinal study. Br J Clin Psychol 1994;33:101-113. https://doi.org/10.1111/j.2044-8260.1994.tb01100.x
  • 21. Dağkıran M, Sürmelioğlu Ö, Özlem A. Diagnosis and treatment approach in benign paroxysmal positional vertigo. Archiv Med Rev J 2015;24:555-564. https://doi.org/10.17827/aktd.66259

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Orjinal Araştırma
Yazarlar

Turgut DOLANBAY (Sorumlu Yazar)
Kafkas Üniversitesi
0000-0002-4092-1192
Türkiye


Levent ŞAHİN
Kafkas Üniversitesi
0000-0003-0193-4393
Türkiye


Hüseyin Fatih GÜL
Kafkas Üniversitesi
0000-0002-9828-1298
Türkiye


Murat ARAS
Kafkas Üniversitesi
0000-0002-4329-4147
Türkiye


Gönül Şeyda SEYDEL
Niğde Ömer Halisdemir Universitesi
0000-0001-9317-0719
Türkiye

Yayımlanma Tarihi 20 Kasım 2021
Kabul Tarihi 25 Ağustos 2021
Yayınlandığı Sayı Yıl 2021, Cilt 11, Sayı 6

Kaynak Göster

AMA Dolanbay T. , Şahin L. , Gül H. F. , Aras M. , Seydel G. Ş. Assessment of Blood Inflamatory Parameters in Elderly Patients With Peripheral Vertigo. J Contemp Med. 2021; 11(6): 822-826.