The Digital Twin for Personalised Medicine: A Systematic Review

Abstract

Personalized medicine is a health model that is gaining traction in all areas of medicine. The digital twin is seen as a complementary strategy for this model. The use of a digital twin for personalized medicine involves the patient, the digital copy of the patient and the interaction between the two. With these models, many diseases can be recognized and prevented before they occur. The aim of this study is to provide a framework to see the suitability, benefits, challenges, problems and application areas of digital twins for personalized medicine. In this context, systematic review method was used. Pubmed and Scopus databases were utilized in the study. The design of the study was created by following the steps in the PRISMA checklist and flow diagram. Searches were conducted using specific inclusion and exclusion criteria. After the searches were completed, 14 studies were included in the full text review. As a result of the study, it was seen that digital twins for personalized medicine are applicable in many medical fields, have many benefits such as reducing costs and improving health, but there are many challenges and problems such as complex patterns, privacy, cost, discrimination. It is recommended to apply this study in an experimental setting to get better results

Keywords

• Digital twin
• Personalised medicine
• Health

Kişiselleştirilmiş Tıp İçin Dijital İkiz: Sistematik Derleme

Öz

Amaç: Kişiselleştirilmiş tıp için dijital ikizlerin uygunluğu, faydaları, zorlukları, sorunları, kişiselleştirilmiş tıptaki uygulama alanlarını görmeye yarayacak bir çerçeve sağlamaktır. Gereç ve Yöntem: Bu bağlamda sistematik derleme yöntemi kullanılmıştır. Çalışmada Pubmed ve Scopus veri tabanlarından faydalanılmıştır. Çalışmanın tasarımı PRISMA kontrol listesi ve akış diyagramındaki adımlar takip edilerek oluşturulmuştur. Belirli dahil etme ve dışlama kriterleri kullanılarak aramalar yapılmıştır. Bulgular: Aramalar bittikten sonra elemeler yapılmış ve 14 çalışma tam metin incelemesine dahil edilmiştir. Sonuç: Çalışma sonucunda kişiselleştirilmiş tıp için dijital ikizlerin birçok tıp alanında uygulanabilir olduğu, maliyetleri düşürmek ve sağlığı iyileştirmek gibi birçok faydalarının olduğu, karmaşık örüntüler, mahremiyet, maliyet, ayrımcılık gibi birçok zorluk ve sorunun olduğu görülmüştür. Daha iyi sonuçlar alabilmek için bu çalışmanın deneysel ortamda uygulanması önerilmektedir.

Anahtar Kelimeler

• Dijital ikiz
• Kişiselleştirilmiş tıp
• Sağlık

Kaynakça

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