Two Cases of Hantavirus Infection in Crimean-Congo Haemorrhagic Fever Endemic Region

Abstract

Mustafa Sunbul, Hava Yılmaz, Hasan Çetinkaya, Yavuz Uyar, Dilek Çaglayık, Fatih Bostancı, Hakan Leblebicioglu Crimean-Congo Hemorrhagic Fever (CCHF) and Leptospirosis are endemic in our region. Hantavirus infections may be confused with similar clinical picture zoonotic infections. Two patients with fever, malaise, cough, phlegm, nausea, vom- iting, thrombocytopenia, renal failure, elevated transaminases, and a history of mouse contact were hospitalized in our clinic with a presumptive diagnosis of leptospirosis, pneumonia, CCHF and Hantavirus infections. Empirical antibiotic treatment was initiated and CCHF and leptospirosis was ruled out with laboratory tests. Hantavirus immunoglobulin (Ig)-G and Ig-M antibodies were detected positive by immunoluorescent antibody (IFA) method in both cases but, Dobrova virus was detected in only one patient with immunoblotting methods. Both patients were discharged after treatment. Hantavirus infections may be misdiagnosed as zoonotic infections since they have similar clinical picture. It should be considered in the differential diagnosis of patients with a history of contact with mouse.

Keywords

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Two Cases of Hantavirus Infection in Crimean-Congo Haemorrhagic Fever Endemic Region

Öz

Anahtar Kelimeler

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Kaynakça

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