Drug-induced
liver injury is one of the most significant adverse drugs reactions and, in
severe cases, could be a potentially life-threatening condition. It can be
classified in intrinsic and idiosyncratic reactions and, anti-tuberculous drugs
are known to induce the later one. In some cases, it might develop some
autoimmune features which represent a challenge for both diagnosis and
treatment. We report a 37-year-old woman who was admitted to our hospital with
signs of severe acute liver injury. She was diagnosed with autoimmune-like
drug-induced liver injury by anti-tuberculous drugs and was treated with
corticosteroids, N-Acetylcysteine and Ursodesoxycholic acid. Indeed, based on
this case a review of the literature is presented. J Microbiol Infect Dis 2018; 8(3):128-134
Anti-tuberculous drugs; Corticosteroids; Drug-induced Liver Injury N-Acetylcysteine Tuberculosis
Birincil Dil | İngilizce |
---|---|
Bölüm | Olgu Sunumu |
Yazarlar | |
Yayımlanma Tarihi | 15 Eylül 2018 |
Yayımlandığı Sayı | Yıl 2018 Cilt: 08 Sayı: 03 |