Epidemiology of Candida colonization in medical surgical intensive care unit of a tertiary care teaching hospital of North India

Yıl 2018, Cilt: 08 Sayı: 04, 147 - 152, 15.12.2018

Afzal Azim Armin Ahmed Arvind Kumar Baronia Reema Yadav Preeti Sharma Rungmei S. K. Marak

https://doi.org/10.5799/jmid.493851

Öz

Objective: Invasive candidiasis is associated with increased
morbidity and mortality in critically ill patients. Current study was undertaken
to study the colonization trend in critically ill patients admitted to a
medical /surgical ICU of a tertiary care teaching hospital.

Methodology: Data for the current study has been derived from a
larger database generated for external validation of risk prediction scores for
invasive candidiasis conducted in a 12 bedded medical/surgical ICU of a
tertiary care hospital of North India. Non neutropenic adult patients with
>48 hours of ICU stay were included in the study. Colonization surveillance
samples were collected from oral cavity, endotracheal aspirates, axilla,
perineum and urine at the time of admission and then on 3^rd, 7^th,
14^th and 21^st day of ICU stay. Blood culture samples were
taken at admission and then as per physician’s discretion.

Results:
Total 200 patients were enrolled from July 2013 to November 2014. Ninety five
percent patients were colonized with Candida
either at admission or during their stay in ICU. The most common species
responsible for colonization was Candida
glabrata (27%) followed by C.
tropicalis (20.5%) and C. auris
(18%). Seventeen patients developed Candida
blood stream infection. C. tropicalis
was the most common species causing candidemia. C.auris was most frequent
colonizer of axilla (54.2%), while rectal swabs had high growth of C. glabrata (44.9%).

Conclusion: Our study population had high rate of Candida colonization. C. glabrata was the most common
colonizer followed by C. tropicalis.  J
Microbiol Infect Dis 2018; 8(4):147-152.

Anahtar Kelimeler

Candida auri, Candida colonization, Candida glabrata, Candida tropicalis; critically ill

Kaynakça

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