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Yıl 2020, Cilt: 10 Sayı: 02, 98 - 102, 29.11.2020
https://doi.org/10.5799/jmid.748721

Öz

Kaynakça

  • 1. Verma A, Weigel KS, Dexter SYK, Dhawan A. Evolution in the management of invasive fungal infections in liver transplant recipient. OBM Transplantation 2018; 2, (2). doi:10.21926/obm.transplant.1802009 2. Pappas PG, Alexander BD, Andes DR, et al. Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). Clin Infect Dis 2010; 50:1101-1111. 3. Girmenia C, Pagano L, Martino B, et al. Invasive infections caused by Trichosporon species and Geotrichum capitatum in patients with hematological malignancies: a retrospective multicenter study from Italy and review of the literature. J Clin Microbiol. 2005; 43 (4):1818-1828. 4. Mazzocato S, Marchionni E, Fothergill AW, et al. Epidemiology and outcome of systemic infections due to Saprochaete capitata: case report and review of the literature. Infection. 2014; 43: 211-215. 5. Döğen A, Kaplan E, Öksüz Z, Serin MS, lkit M, de Hoog GS. Dishwashers are a major source of human opportunistic yeast-like fungi in indoor environments in Mersin, Turkey. Med Mycol 2013; 51:493-498. 6. Arendrup MC, Boekhout T, Akova M, et al . ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections. European Society of Clinical Microbiology and Infectious Diseases Fungal Infection Study Group; European Confederation of Medical Mycology. Clin Microbiol Infect 2014; 20:76-98. 7. Pickering JW; Sant HW, Bowles CA, Roberts, WL, Woods GL. Evaluation of a (1,3)-β-D-glucan assay for diagnosis of invasive fungal infections. J. Clin. Microbiol 2005; 43:5957–5962. 8. Levesque E, Rizk F, Noorah Z, et al. Detection of (1,3)-β-D-Glucan for the Diagnosis of Invasive Fungal Infection in Liver Transplant Recipients. Int J Mol Sci 2017; 18(4):862. 9. McCarthy MW, Petraitiene R, Walsh TJ. Translational Development and Application of (1,3)-β-d-Glucan for Diagnosis and Therapeutic Monitoring of Invasive Mycoses. International Journal of Molecular Sciences 2017; 18(6), doi: 10.3390/ijms18061124. 10. He S, Hang JP, Zhang L, Wang F, Zhang DC, Gong FH. A systematic review and meta-analysis of diagnostic accuracy of serum 1,3-beta-D-glucan for invasive fungal infection: Focus on cutoff levels. J Microbiol Immunol Infect 2015; 48(4):351-361. 11. Özkaya-Parlakay A, Cengiz AB, Karadağ-Öncel E, et al. Geotrichum capitatum septicemia in a hematological malignancy patient with positive galactomannan antigen: case report and review of the literature.

Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection

Yıl 2020, Cilt: 10 Sayı: 02, 98 - 102, 29.11.2020
https://doi.org/10.5799/jmid.748721

Öz

Invasive fungal infection (IFI) with Magnusiomyces capitatus is rare, occurring mainly in patients with hematological diseases. We report first case of tissue invasive M. capitatus infection in a liver transplant recipient (LTR) and use of an IFI biomarker beta-D glucan (BDG) for monitoring antifungal therapy.
A 59 year old male received 3rd liver transplant (LT) for primary sclerosing cholangitis and developed invasive tissue disease due to M. capitatus. BDG was done weekly to monitor the antifungal therapy. However in the 5th week there was sudden rise in BDG >523pg/ml despite dual antifungal. This was used as a guide to investigate for further persistence of focus for IFI and source control. M. capitatus was intermediate resistant to voriconazole and echinocandins. Voriconazole was stopped and LAmB was continued for 6 month. In our experience, biomarker BDG is proved helpful for diagnosis, monitoring the therapeutic efficacy and used as guide to decide the duration of antifungal therapy. J Microbiol Infect Dis 2020; 10(2):98-102.

Kaynakça

  • 1. Verma A, Weigel KS, Dexter SYK, Dhawan A. Evolution in the management of invasive fungal infections in liver transplant recipient. OBM Transplantation 2018; 2, (2). doi:10.21926/obm.transplant.1802009 2. Pappas PG, Alexander BD, Andes DR, et al. Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). Clin Infect Dis 2010; 50:1101-1111. 3. Girmenia C, Pagano L, Martino B, et al. Invasive infections caused by Trichosporon species and Geotrichum capitatum in patients with hematological malignancies: a retrospective multicenter study from Italy and review of the literature. J Clin Microbiol. 2005; 43 (4):1818-1828. 4. Mazzocato S, Marchionni E, Fothergill AW, et al. Epidemiology and outcome of systemic infections due to Saprochaete capitata: case report and review of the literature. Infection. 2014; 43: 211-215. 5. Döğen A, Kaplan E, Öksüz Z, Serin MS, lkit M, de Hoog GS. Dishwashers are a major source of human opportunistic yeast-like fungi in indoor environments in Mersin, Turkey. Med Mycol 2013; 51:493-498. 6. Arendrup MC, Boekhout T, Akova M, et al . ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections. European Society of Clinical Microbiology and Infectious Diseases Fungal Infection Study Group; European Confederation of Medical Mycology. Clin Microbiol Infect 2014; 20:76-98. 7. Pickering JW; Sant HW, Bowles CA, Roberts, WL, Woods GL. Evaluation of a (1,3)-β-D-glucan assay for diagnosis of invasive fungal infections. J. Clin. Microbiol 2005; 43:5957–5962. 8. Levesque E, Rizk F, Noorah Z, et al. Detection of (1,3)-β-D-Glucan for the Diagnosis of Invasive Fungal Infection in Liver Transplant Recipients. Int J Mol Sci 2017; 18(4):862. 9. McCarthy MW, Petraitiene R, Walsh TJ. Translational Development and Application of (1,3)-β-d-Glucan for Diagnosis and Therapeutic Monitoring of Invasive Mycoses. International Journal of Molecular Sciences 2017; 18(6), doi: 10.3390/ijms18061124. 10. He S, Hang JP, Zhang L, Wang F, Zhang DC, Gong FH. A systematic review and meta-analysis of diagnostic accuracy of serum 1,3-beta-D-glucan for invasive fungal infection: Focus on cutoff levels. J Microbiol Immunol Infect 2015; 48(4):351-361. 11. Özkaya-Parlakay A, Cengiz AB, Karadağ-Öncel E, et al. Geotrichum capitatum septicemia in a hematological malignancy patient with positive galactomannan antigen: case report and review of the literature.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunumu
Yazarlar

Shrijit Nair Bu kişi benim

Rosa Miquel Bu kişi benim

Wayel Jassem Bu kişi benim

Anita Verma Bu kişi benim

Abid Suddle Bu kişi benim

Yayımlanma Tarihi 29 Kasım 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 10 Sayı: 02

Kaynak Göster

APA Nair, S., Miquel, R., Jassem, W., Verma, A., vd. (2020). Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection. Journal of Microbiology and Infectious Diseases, 10(02), 98-102. https://doi.org/10.5799/jmid.748721
AMA Nair S, Miquel R, Jassem W, Verma A, Suddle A. Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection. J Microbil Infect Dis. Kasım 2020;10(02):98-102. doi:10.5799/jmid.748721
Chicago Nair, Shrijit, Rosa Miquel, Wayel Jassem, Anita Verma, ve Abid Suddle. “Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces Capitatus Infection”. Journal of Microbiology and Infectious Diseases 10, sy. 02 (Kasım 2020): 98-102. https://doi.org/10.5799/jmid.748721.
EndNote Nair S, Miquel R, Jassem W, Verma A, Suddle A (01 Kasım 2020) Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection. Journal of Microbiology and Infectious Diseases 10 02 98–102.
IEEE S. Nair, R. Miquel, W. Jassem, A. Verma, ve A. Suddle, “Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection”, J Microbil Infect Dis, c. 10, sy. 02, ss. 98–102, 2020, doi: 10.5799/jmid.748721.
ISNAD Nair, Shrijit vd. “Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces Capitatus Infection”. Journal of Microbiology and Infectious Diseases 10/02 (Kasım 2020), 98-102. https://doi.org/10.5799/jmid.748721.
JAMA Nair S, Miquel R, Jassem W, Verma A, Suddle A. Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection. J Microbil Infect Dis. 2020;10:98–102.
MLA Nair, Shrijit vd. “Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces Capitatus Infection”. Journal of Microbiology and Infectious Diseases, c. 10, sy. 02, 2020, ss. 98-102, doi:10.5799/jmid.748721.
Vancouver Nair S, Miquel R, Jassem W, Verma A, Suddle A. Use of Beta-D-Glucan for Monitoring Antifungal Therapy of a Multidrug Resistant Invasive Magnusiomyces capitatus Infection. J Microbil Infect Dis. 2020;10(02):98-102.