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Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases

Yıl 2021, Cilt: 11 Sayı: 02, 108 - 113, 15.06.2021
https://doi.org/10.5799/jmid.951625

Öz

Coronavirus disease 2019 (Covid-19) is a highly infectious disease, and its replication decreasing rapidly after the first week, while some level of immunity is built up. A small proportion of discharged patients may become positive again for severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) RNA, even if they meet the discharge criteria. Re-infection of SARS-CoV-2 is an apparently uncommon entity and only a few case reports or case series have been reported from across the whole world. Herein, we have reported two rare Covid-19 cases with recurrence of positive SARS-CoV-2 RNA after a complete clinical cure. The first case was redetected with Covid-19 with more severity after a gap of approximately three weeks after cure, and the second case has recurred after approximately seven weeks with a complication of pulmonary thromboembolism. We report here, the first few cases of a more vigorous Covid-19 recurrence with SARS-CoV-2 RNA in India. J Microbiol Infect Dis 2021; 11(2):108-114.

Kaynakça

  • 1) Gousseff M, Penot P, Gallay L, et al. Clinical recurrences of Covid-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound. J Infect 2020; S0163-4453(20):30454-60.
  • 2) World Health Organization. Coronavirus disease (Covid-19) outbreak situation. https://covid19.who.int/ (accessed 26 September 2020).
  • 3) Grifoni A, Weiskopf D, Ramirez SI, Mateus J, Dan JM, Moderbacher CR. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with Covid-19 Disease and Unexposed Individuals. Cell 2020; 181(7):1489–01.
  • 4) Cao H, Ruan L, Liu J, Liao W. The clinical characteristic of eight patients of Covid-19 with positive RT-PCR test after discharge. J Med Virol 2020; 92(10):2159-64.
  • 5) Hoang VT, Dao TL, Gautret P. Recurrence of positive SARS-CoV-2 in patients recovered from COVID-19. J Med Virol 2020; 92(11):2366-2367.
  • 6) World Health Organization. Real-Time RT-PCR Panel for Detection 2019-Novel Coronavirus 2020. https://www.who.int/docs/default-source/coronaviruse/uscdcrt-pcr-panel-for-detection-instructions.pdf? sfvrsn =3aa 07934_2.
  • 7) Wang Y, Wang Y, Chen Y, Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (Covid-19) implicate special control measures. J Med Virol 2020; 92(6):568-76.
  • 8) Kang H, Wang Y, Tong Z, Liu X. Retest positive for SARS CoV-2 RNA of “recovered” patients with Covid-19: Persistence, sampling issues, or re-infection? J Med Virol 2020; 92(11):2263-65.
  • 9) Xiao AT, Tong YX, Zhang S. False-negative of RT-PCR and prolonged nucleic acid conversion in Covid-19: Rather than recurrence. J Med Virol 2020; 92(10):1755–56.
  • 10) Chen D, Xu W, Lei Z, et al. Recurrence of positive SARS-CoV-2 RNA in Covid-19: A case report. Int J Infect Dis 2020; 93:297-299.
  • 11) Ye G, Pan Z, Pan Y, et al. Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation. J Infect 2020; 80(5):e14-e17.
  • 12) Long Q, Liu B, Deng H. et al. Antibody responses to SARS-CoV-2 in patients with Covid-19. Nat Med 2020; 26:845–48.
  • 13) Lin YC, Cheng CY, Chen CP. et al. A case of transient existence of SARS- CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response. Int J Infect Dis 2020; 96:464-66.
  • 14) Lan L, Xu D, Ye G, et al. Positive RT-PCR Test Results in Patients Recovered from Covid-19. JAMA 2020; 323(15):1502-03.
  • 15) Loconsole D, Passerini F, Palmieri VO, et al. Recurrence of Covid-19 after recovery: a case report from Italy. Infection 2020; 48(6):965–967.
  • 16) Rothe C, Schunk M, Sothmann P, et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. N Engl J Med 2020; 382(10):970-71. 17) Xie X, Zhong Z, Zhao W, et al. Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing. Radiology 2020; 296(2): E41-E45.
Yıl 2021, Cilt: 11 Sayı: 02, 108 - 113, 15.06.2021
https://doi.org/10.5799/jmid.951625

Öz

Kaynakça

  • 1) Gousseff M, Penot P, Gallay L, et al. Clinical recurrences of Covid-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound. J Infect 2020; S0163-4453(20):30454-60.
  • 2) World Health Organization. Coronavirus disease (Covid-19) outbreak situation. https://covid19.who.int/ (accessed 26 September 2020).
  • 3) Grifoni A, Weiskopf D, Ramirez SI, Mateus J, Dan JM, Moderbacher CR. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with Covid-19 Disease and Unexposed Individuals. Cell 2020; 181(7):1489–01.
  • 4) Cao H, Ruan L, Liu J, Liao W. The clinical characteristic of eight patients of Covid-19 with positive RT-PCR test after discharge. J Med Virol 2020; 92(10):2159-64.
  • 5) Hoang VT, Dao TL, Gautret P. Recurrence of positive SARS-CoV-2 in patients recovered from COVID-19. J Med Virol 2020; 92(11):2366-2367.
  • 6) World Health Organization. Real-Time RT-PCR Panel for Detection 2019-Novel Coronavirus 2020. https://www.who.int/docs/default-source/coronaviruse/uscdcrt-pcr-panel-for-detection-instructions.pdf? sfvrsn =3aa 07934_2.
  • 7) Wang Y, Wang Y, Chen Y, Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (Covid-19) implicate special control measures. J Med Virol 2020; 92(6):568-76.
  • 8) Kang H, Wang Y, Tong Z, Liu X. Retest positive for SARS CoV-2 RNA of “recovered” patients with Covid-19: Persistence, sampling issues, or re-infection? J Med Virol 2020; 92(11):2263-65.
  • 9) Xiao AT, Tong YX, Zhang S. False-negative of RT-PCR and prolonged nucleic acid conversion in Covid-19: Rather than recurrence. J Med Virol 2020; 92(10):1755–56.
  • 10) Chen D, Xu W, Lei Z, et al. Recurrence of positive SARS-CoV-2 RNA in Covid-19: A case report. Int J Infect Dis 2020; 93:297-299.
  • 11) Ye G, Pan Z, Pan Y, et al. Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation. J Infect 2020; 80(5):e14-e17.
  • 12) Long Q, Liu B, Deng H. et al. Antibody responses to SARS-CoV-2 in patients with Covid-19. Nat Med 2020; 26:845–48.
  • 13) Lin YC, Cheng CY, Chen CP. et al. A case of transient existence of SARS- CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response. Int J Infect Dis 2020; 96:464-66.
  • 14) Lan L, Xu D, Ye G, et al. Positive RT-PCR Test Results in Patients Recovered from Covid-19. JAMA 2020; 323(15):1502-03.
  • 15) Loconsole D, Passerini F, Palmieri VO, et al. Recurrence of Covid-19 after recovery: a case report from Italy. Infection 2020; 48(6):965–967.
  • 16) Rothe C, Schunk M, Sothmann P, et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. N Engl J Med 2020; 382(10):970-71. 17) Xie X, Zhong Z, Zhao W, et al. Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing. Radiology 2020; 296(2): E41-E45.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunumu
Yazarlar

Amresh Kumar Singh Bu kişi benim

Ankur Kumar Bu kişi benim

Vivek Gaur Bu kişi benim

Indra Prasad Adhikari Bu kişi benim

Raj Kishore Singh Bu kişi benim

Yayımlanma Tarihi 15 Haziran 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 11 Sayı: 02

Kaynak Göster

APA Singh, A. K., Kumar, A., Gaur, V., Adhikari, I. P., vd. (2021). Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases. Journal of Microbiology and Infectious Diseases, 11(02), 108-113. https://doi.org/10.5799/jmid.951625
AMA Singh AK, Kumar A, Gaur V, Adhikari IP, Singh RK. Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases. J Microbil Infect Dis. Haziran 2021;11(02):108-113. doi:10.5799/jmid.951625
Chicago Singh, Amresh Kumar, Ankur Kumar, Vivek Gaur, Indra Prasad Adhikari, ve Raj Kishore Singh. “Recurrence of SARS-CoV-2 RNA Among Positive Covid-19 Cases”. Journal of Microbiology and Infectious Diseases 11, sy. 02 (Haziran 2021): 108-13. https://doi.org/10.5799/jmid.951625.
EndNote Singh AK, Kumar A, Gaur V, Adhikari IP, Singh RK (01 Haziran 2021) Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases. Journal of Microbiology and Infectious Diseases 11 02 108–113.
IEEE A. K. Singh, A. Kumar, V. Gaur, I. P. Adhikari, ve R. K. Singh, “Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases”, J Microbil Infect Dis, c. 11, sy. 02, ss. 108–113, 2021, doi: 10.5799/jmid.951625.
ISNAD Singh, Amresh Kumar vd. “Recurrence of SARS-CoV-2 RNA Among Positive Covid-19 Cases”. Journal of Microbiology and Infectious Diseases 11/02 (Haziran 2021), 108-113. https://doi.org/10.5799/jmid.951625.
JAMA Singh AK, Kumar A, Gaur V, Adhikari IP, Singh RK. Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases. J Microbil Infect Dis. 2021;11:108–113.
MLA Singh, Amresh Kumar vd. “Recurrence of SARS-CoV-2 RNA Among Positive Covid-19 Cases”. Journal of Microbiology and Infectious Diseases, c. 11, sy. 02, 2021, ss. 108-13, doi:10.5799/jmid.951625.
Vancouver Singh AK, Kumar A, Gaur V, Adhikari IP, Singh RK. Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases. J Microbil Infect Dis. 2021;11(02):108-13.