BibTex RIS Kaynak Göster

Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression

Yıl 2015, Cilt: 5 Sayı: 01, 25 - 28, 30.04.2015
https://doi.org/10.5799/ahinjs.02.2015.01.0170

Öz

Necrotizing Fasciitis (NF) is a life-threatening infectious emergency, characterized by rapidly progressive fascia and sub-cutaneous tissue necrosis. NF carries a high mortality rate in the neutropenic period of immunosuppressive patients, not because of co-morbidity but also because antibiotics frequently administered are typically ineffective. Here, we report three cases of NF caused by multi-drug resistant Pseudomonas aeruginosa (only colistin susceptible) and Stenotrophomonas maltophilia, which both restricts our treatment options. The cases underline the importance of recognition and early intervention of NF in patients with immunosuppression which may be difficult because of concealed sign and symptoms.

Kaynakça

  • Gündeş S. Nekrotizan fasiyit. In: Ulusoy S, ed. Komplike deri ve yumuşak doku enfeksiyonları: Yeni perspektifler. Ankara: Bilimsel Tıp Kitabevleri, 2009:7-12.
  • Gündeş S. Nekrotizan fasiyit. In: Leblebicioğlu H, Usluer G, Sercan Ulusoy, eds. Güncel bilgiler ışığında antimikrobiyal tedavi, Ankara: Bilimsel Tıp Kitabevleri, 2012:23-28.
  • Mantadakis E, Pontikoglou C, Papadaki AH, et al. Fatal Fournier’s gangrene in a young adult with acute lymphoblas- tic leukemia. Pediatr Blood Cancer 2007;49:862-864.
  • Lee CC, Chi CH, Lee NY, et al. Necrotizing fasciitis in pa- tients with liver cirrhosis: predominance of monomicrobial gram-negative bacillary infections. Diagn Microbiol Infect Dis 2008;62:219-225.
  • Naithani R, Kumar R, Mahapatra M. Fournier’s gangrene and scrotal ulcerations during all-trans-retinoic acid therapy for acute promyelocytic leukemia. Pediatr Blood Cancer 2008;51:303-304.
  • Kaya H, Yoshida T. A case of intravascular lymphoma com- plicated with Fournier’s syndrome due to multidrug-resistant Pseudomonas aeruginosa. J Clin Exp Hematol 2011;51:115- 118.
  • Zhao GJ, Hong GL, Liu JQ, et al. Septic shock due to com- munity-acquired Pseudomonas aeruginosa necrotizing fasciitis: A case report and literature review. Exp Ther Med 2014;7:1545-1548.
  • Teo WY, Chan MY, Lam CM, Chong CY. Skin manifestation of Stenotrophomonas maltophilia infection--a case report and review article. Ann Acad Med Singapore 2006;35: 897-900.
  • Gündeş S. Komplike deri ve yumuşak doku enfeksiyonları. In: Ulusoy S, ed. Tedavi seçenekleri ve tigesiklin’nin tedavideki yeri.Ankara : Bilimsel Tıp Kitabevleri, 2013;13-21.

Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression

Yıl 2015, Cilt: 5 Sayı: 01, 25 - 28, 30.04.2015
https://doi.org/10.5799/ahinjs.02.2015.01.0170

Öz

Nekrotizan fasiiit (NF), fasya ve subkütan dokuda süratle ilerleyen nekroz ile karakterize, yaşamı tehdit eden bir acil bir enfeksiyon hastalığıdır. NF, immunsüpresif hastaların nötropenik döneminde, hem ko-morbid durum hem de antibiyotik yanıtının yetersizliğinden dolayı yüksek mortaliteye sahiptir. Burada, antibiyotik tedavisinin kısıtlı olduğu, çoklu ilaca dirençli Pseudomonas aeruginosa (sadece kolistin duyarlı) ve Stenotrophomonas maltophilia’nın neden olduğu üç NF olgusu sunulmuştur. Olgular, immunsüpresif hastalarda, belirti ve bulguların silik olmasından dolayı zor tanınabilecek NF takibinde erken tanı ve müdahalenin önemini vurgulamaktadır

Kaynakça

  • Gündeş S. Nekrotizan fasiyit. In: Ulusoy S, ed. Komplike deri ve yumuşak doku enfeksiyonları: Yeni perspektifler. Ankara: Bilimsel Tıp Kitabevleri, 2009:7-12.
  • Gündeş S. Nekrotizan fasiyit. In: Leblebicioğlu H, Usluer G, Sercan Ulusoy, eds. Güncel bilgiler ışığında antimikrobiyal tedavi, Ankara: Bilimsel Tıp Kitabevleri, 2012:23-28.
  • Mantadakis E, Pontikoglou C, Papadaki AH, et al. Fatal Fournier’s gangrene in a young adult with acute lymphoblas- tic leukemia. Pediatr Blood Cancer 2007;49:862-864.
  • Lee CC, Chi CH, Lee NY, et al. Necrotizing fasciitis in pa- tients with liver cirrhosis: predominance of monomicrobial gram-negative bacillary infections. Diagn Microbiol Infect Dis 2008;62:219-225.
  • Naithani R, Kumar R, Mahapatra M. Fournier’s gangrene and scrotal ulcerations during all-trans-retinoic acid therapy for acute promyelocytic leukemia. Pediatr Blood Cancer 2008;51:303-304.
  • Kaya H, Yoshida T. A case of intravascular lymphoma com- plicated with Fournier’s syndrome due to multidrug-resistant Pseudomonas aeruginosa. J Clin Exp Hematol 2011;51:115- 118.
  • Zhao GJ, Hong GL, Liu JQ, et al. Septic shock due to com- munity-acquired Pseudomonas aeruginosa necrotizing fasciitis: A case report and literature review. Exp Ther Med 2014;7:1545-1548.
  • Teo WY, Chan MY, Lam CM, Chong CY. Skin manifestation of Stenotrophomonas maltophilia infection--a case report and review article. Ann Acad Med Singapore 2006;35: 897-900.
  • Gündeş S. Komplike deri ve yumuşak doku enfeksiyonları. In: Ulusoy S, ed. Tedavi seçenekleri ve tigesiklin’nin tedavideki yeri.Ankara : Bilimsel Tıp Kitabevleri, 2013;13-21.
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Olgu Sunumu
Yazarlar

Aynur Aynioglu Bu kişi benim

Elif Sargin Altunok Bu kişi benim

Esra Ulukaya Bu kişi benim

Sibel Gundes Bu kişi benim

Yayımlanma Tarihi 30 Nisan 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 5 Sayı: 01

Kaynak Göster

APA Aynioglu, A., Altunok, E. S., Ulukaya, E., Gundes, S. (2015). Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression. Journal of Microbiology and Infectious Diseases, 5(01), 25-28. https://doi.org/10.5799/ahinjs.02.2015.01.0170
AMA Aynioglu A, Altunok ES, Ulukaya E, Gundes S. Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression. J Microbil Infect Dis. Mart 2015;5(01):25-28. doi:10.5799/ahinjs.02.2015.01.0170
Chicago Aynioglu, Aynur, Elif Sargin Altunok, Esra Ulukaya, ve Sibel Gundes. “Three Cases of Necrotising Fasciitis Caused by Pseudomonas Aeruginosa and Stenotrophomonas Maltophilia: The Importance of Immunosuppression”. Journal of Microbiology and Infectious Diseases 5, sy. 01 (Mart 2015): 25-28. https://doi.org/10.5799/ahinjs.02.2015.01.0170.
EndNote Aynioglu A, Altunok ES, Ulukaya E, Gundes S (01 Mart 2015) Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression. Journal of Microbiology and Infectious Diseases 5 01 25–28.
IEEE A. Aynioglu, E. S. Altunok, E. Ulukaya, ve S. Gundes, “Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression”, J Microbil Infect Dis, c. 5, sy. 01, ss. 25–28, 2015, doi: 10.5799/ahinjs.02.2015.01.0170.
ISNAD Aynioglu, Aynur vd. “Three Cases of Necrotising Fasciitis Caused by Pseudomonas Aeruginosa and Stenotrophomonas Maltophilia: The Importance of Immunosuppression”. Journal of Microbiology and Infectious Diseases 5/01 (Mart 2015), 25-28. https://doi.org/10.5799/ahinjs.02.2015.01.0170.
JAMA Aynioglu A, Altunok ES, Ulukaya E, Gundes S. Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression. J Microbil Infect Dis. 2015;5:25–28.
MLA Aynioglu, Aynur vd. “Three Cases of Necrotising Fasciitis Caused by Pseudomonas Aeruginosa and Stenotrophomonas Maltophilia: The Importance of Immunosuppression”. Journal of Microbiology and Infectious Diseases, c. 5, sy. 01, 2015, ss. 25-28, doi:10.5799/ahinjs.02.2015.01.0170.
Vancouver Aynioglu A, Altunok ES, Ulukaya E, Gundes S. Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression. J Microbil Infect Dis. 2015;5(01):25-8.