BibTex RIS Kaynak Göster

Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate

Yıl 2015, Cilt: 5 Sayı: 3, 142 - 145, 06.02.2016

Jayashree Purkayastha Leslie Lewis Ramesh Bhat Y Morakhia Jwalit V Ranjan Shetty K Muhammad Najih L

https://doi.org/10.5799/ahijs.02.2015.03.0194
Cited By: 1

Öz

Fungal mycetoma or endocarditis is rare in premature neonates and it is often associated with high mortality. In the majority of the cases diagnosis is made postmortem. Here we report a 30-week-old preterm neonate who developed Candida albicans blood stream infection complicated by endocarditis and subsequent mycetoma. Initially, this neonate had Klebsiella sepsis requiring multiple antibiotic courses. A peripherally inserted central venous catheter was used to give total parenteral nutrition. On day 24 of life, he developed candidemia, treated with 14 day course of fluconazole and shown improvement. Further, on day 60 of life he developed cholestasis, deranged liver function tests and persistent thrombocytopenia along with apnea, bradycardia and desaturations. Blood culture again grew again C. albicans. Echocardiography showed large fungal vegetation on tricuspid valve with a mycetoma filling the right ventricle. He was treated with intravenous amphotericin B, fluconazole and supportive measures, but he deteriorated and succumbed after two weeks. J Microbiol Infect Dis 2015;5(3): 142-145

Key words: Prematureneonate, candida sepsis, endocarditis, mycetoma

Anahtar Kelimeler

Prematureneonate candida sepsis endocarditis mycetoma

Kaynakça

  • Millar BC, Jugo J, Moore JE. Fungal endocarditis in neonates and children. Pediatr Cardiol 2005;26:517-536.
  • Sharma J, Nagaraj A, Allapathy D, et al. Fungal endocarditis
  • in a prematureinfant complicated by a right atrial mycetoma and IVC thrombosis. Images Pediatr Cardiol 2009;11:6-11.
  • Noyola DE, Fernandes M, Moylett E, Baker CJ. Ophthalmologic,
  • visceral and cardiac involvement in neonates with candidemia.Clin Infect Dis 2001;32:1018-1032.
  • Citak M, Rees A, Mavroudis C. Surgical management of infective
  • endocarditis in children. Ann Thorac Surg 1992;54:755-760.
  • Levy I, Shalit I, Birk E, et al. Candida endocarditis in neonates:
  • report of five cases and review of the literature. Mycoses 2006;49:4.
  • Emilio M, Jose M, Juan C, Guarro Josep G. Fungal endocarditis
  • in Premature Infant. Case Report and Review. Clin Infect Dis. 1996;22:366-368.
  • Pappas GP, Kauffman AC, Andes D, et al. Clinical Practice
  • Guidelines for the management of Candidiasis: 2009 Updateby the Infectious Diseases Society of America. Clin Infect Dis 2009;48:503-535.

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Yıl 2015, Cilt: 5 Sayı: 3, 142 - 145, 06.02.2016

Jayashree Purkayastha Leslie Lewis Ramesh Bhat Y Morakhia Jwalit V Ranjan Shetty K Muhammad Najih L

https://doi.org/10.5799/ahijs.02.2015.03.0194
Cited By: 1

Öz

Prematür yenidoğanlarda mantar miçetoma nadirdir ve sıklıkla mortaliteyle sonuçlanır. Olguların çoğunda tanı postmortem konulur. Burada Candida albicans ile kan dolaşımı enfeksiyonu gelişen, ardından endokardit ve miçetoma ile komplike olan 30 haftalık preterm bir yenidoğan olgusunu sunduk. Bu yenidoğanın başlangıçta çoklu antibiyotik kullanmayı gerektiren Klebsiella sepsisi vardı. Total parenteral beslenme için periferden konulan bir santral venöz kateter kullanıldı. Doğumdan sonraki 24. günde kandidemi gelişti, 14 gün süreyle flukonazol ile tedavi edildi ve iyileşme gösterdi. Daha sonra 60. günde kolestaz gelişti ve bozulan karaciğer fonksiyon testleri ve sürekli trombositopeni ile birlikte apne, bradikardi ve satürasyon bozuklukları ortaya çıktı. Kan kültüründe tekrar C. albicans üredi. Ekokardiyografide sağ ventrikülü dolduran bir miçetoma ile triküspid kapak üzerinde büyük bir mantar vejetasyonu görüldü. Damar yoluyla amfoterisin B ve flukonazol tedavisi yanında diğer gereken tıbbı destekler yapıldı ancak hastanın genel durumu bozularak iki hafta sonra kaybedildi

Anahtar Kelimeler

Prematür yenidoğan candida sepsisi endokardit miçetoma

Kaynakça

  • Millar BC, Jugo J, Moore JE. Fungal endocarditis in neonates and children. Pediatr Cardiol 2005;26:517-536.
  • Sharma J, Nagaraj A, Allapathy D, et al. Fungal endocarditis
  • in a prematureinfant complicated by a right atrial mycetoma and IVC thrombosis. Images Pediatr Cardiol 2009;11:6-11.
  • Noyola DE, Fernandes M, Moylett E, Baker CJ. Ophthalmologic,
  • visceral and cardiac involvement in neonates with candidemia.Clin Infect Dis 2001;32:1018-1032.
  • Citak M, Rees A, Mavroudis C. Surgical management of infective
  • endocarditis in children. Ann Thorac Surg 1992;54:755-760.
  • Levy I, Shalit I, Birk E, et al. Candida endocarditis in neonates:
  • report of five cases and review of the literature. Mycoses 2006;49:4.
  • Emilio M, Jose M, Juan C, Guarro Josep G. Fungal endocarditis
  • in Premature Infant. Case Report and Review. Clin Infect Dis. 1996;22:366-368.
  • Pappas GP, Kauffman AC, Andes D, et al. Clinical Practice
  • Guidelines for the management of Candidiasis: 2009 Updateby the Infectious Diseases Society of America. Clin Infect Dis 2009;48:503-535.
Toplam 13 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Olgu Sunumu
Yazarlar

Jayashree Purkayastha Bu kişi benim

Leslie Lewis Bu kişi benim

Ramesh Bhat Y Bu kişi benim

Morakhia Jwalit V Bu kişi benim

Ranjan Shetty K Bu kişi benim

Muhammad Najih L Bu kişi benim

Yayımlanma Tarihi 6 Şubat 2016
Yayımlandığı Sayı Yıl 2015 Cilt: 5 Sayı: 3

Kaynak Göster

APA Purkayastha, J., Lewis, L., Bhat Y, R., Jwalit V, M., vd. (2016). Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. Journal of Microbiology and Infectious Diseases, 5(3), 142-145. https://doi.org/10.5799/ahijs.02.2015.03.0194
AMA Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M. Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. J Microbil Infect Dis. Şubat 2016;5(3):142-145. doi:10.5799/ahijs.02.2015.03.0194
Chicago Purkayastha, Jayashree, Leslie Lewis, Ramesh Bhat Y, Morakhia Jwalit V, Ranjan Shetty K, ve Muhammad Najih L. “Fungal Endocarditis With Right Ventricular Candidal Mycetoma in a Premature Neonate”. Journal of Microbiology and Infectious Diseases 5, sy. 3 (Şubat 2016): 142-45. https://doi.org/10.5799/ahijs.02.2015.03.0194.
EndNote Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M (01 Şubat 2016) Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. Journal of Microbiology and Infectious Diseases 5 3 142–145.
IEEE J. Purkayastha, L. Lewis, R. Bhat Y, M. Jwalit V, R. Shetty K, ve M. Najih L, “Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate”, J Microbil Infect Dis, c. 5, sy. 3, ss. 142–145, 2016, doi: 10.5799/ahijs.02.2015.03.0194.
ISNAD Purkayastha, Jayashree vd. “Fungal Endocarditis With Right Ventricular Candidal Mycetoma in a Premature Neonate”. Journal of Microbiology and Infectious Diseases 5/3 (Şubat 2016), 142-145. https://doi.org/10.5799/ahijs.02.2015.03.0194.
JAMA Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M. Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. J Microbil Infect Dis. 2016;5:142–145.
MLA Purkayastha, Jayashree vd. “Fungal Endocarditis With Right Ventricular Candidal Mycetoma in a Premature Neonate”. Journal of Microbiology and Infectious Diseases, c. 5, sy. 3, 2016, ss. 142-5, doi:10.5799/ahijs.02.2015.03.0194.
Vancouver Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M. Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. J Microbil Infect Dis. 2016;5(3):142-5.

Cited By

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Journal of Pure and Applied Microbiology
Lakshyasri Baishya
https://doi.org/10.22207/JPAM.11.2.38