Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study

Hayriye Cankar Dal

EN TR

Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study

Öz

COVID-19 Pandemisinde Beyin Ölümü ve Organ Bağışı: Retrospektif Gözlemsel Çalışma

Öz

Amaç: COVİD-19 pandemisi dünya genelinde olduğu gibi ülkemizde de organ nakli süreçlerini etkilemiştir. Bu çalışma ile pandemi döneminde bölgedeki en büyük referans pandemi hastanesindeki beyin ölümü ve kadaverik organ donasyonu olgularının değerlendirilmesi amaçlanmıştır. Gereç ve yöntem: 11.3.2020-11.3.2021 tarihleri arasında hastanemizde tanı koyulan tüm beyin ölümü olguları retrospektif olarak değerlendirilmiştir. Demografik özellikler, aile onay oranları ve COVID-19 ekartasyonu açısından yapılan ek değerlendirmeler dahil olmak üzere hasta verileri analiz edildi. Deklarasyon ve donasyon süreleri, donor sayısı ve organların kullanılabilirlik oranları incelenmiştir. Ayrıca, aile onayı olmasına rağmen tıbbi nedenlerle organları kullanılamayan olgular, bu sonucun altta yatan nedenleri açısından değerlendirildi. Bulgular: Çalışmaya 26 erişkin beyin ölümü olgusu dahil edilmiştir. Yedi (%26.9) hastada aile onayı mevcuttu. Aile onamı olan 7 olgunun 3’ünün organları transplante edilmiştir. Geri kalan olgulardan bir olgunun alınan ikinci RT-PCR testi pozitifti. Diğer olgularda her iki RT-PCR negatif olmasına rağmen laboratuar tetkikleri ve donasyon öncesi çekilen toraks tomografilerinde COVID-19 ekarte edilememişti, ayrıca kan kültürlerinde bakteriyemi mevcuttu. Donor olmayanların medyan lenfosit sayısı (0.665 × 109/L [0.340-0.770]), donorlere göre (1.182 ×109/L [1.050-1.780]) anlamı olarak düşüktü (p <0.05). Ayrıca prokalsitonin düzeyleri donor olmayanlarda (10.48 μg/L [3.19-26.68]) anlamlı olarak daha yüksek saptandı (p <0.05). Sonuç: COVID-19 pandemisi transplantasyon süreçlerini büyük oranda etkilemiştir. Bu dönemde COVID-19 ekartasyonu açısından yapılan ek değerlendirmelere bağlı uzamış yoğun bakım yatış süreleri ve beraberinde gelişebilecek yoğun bakım kaynaklı enfeksiyonların, donor kaybı oranlarını artırabileceği göz önünde bulundurulmalıdır.

Anahtar Kelimeler

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Organ Nakli , Anesteziyoloji, Yoğun Bakım

Bölüm

Araştırma Makalesi

Yazarlar

Hayriye Cankar Dal ^*
0000-0003-4744-9959
Türkiye

Yayımlanma Tarihi

30 Nisan 2022

Gönderilme Tarihi

1 Mart 2022

Kabul Tarihi

24 Mart 2022

Yayımlandığı Sayı

Yıl 2022 Cilt: 5 Sayı: 1

IZ

https://izlik.org/JA28UX86SU

Kaynak Göster

RIS / Bibtex

APA

Cankar Dal, H. (2022). Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study. Journal of Cukurova Anesthesia and Surgical Sciences, 5(1), 33-42. https://izlik.org/JA28UX86SU

AMA

1.Cankar Dal H. Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study. J Cukurova Anesth Surg. 2022;5(1):33-42. https://izlik.org/JA28UX86SU

Chicago

Cankar Dal, Hayriye. 2022. “Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study”. Journal of Cukurova Anesthesia and Surgical Sciences 5 (1): 33-42. https://izlik.org/JA28UX86SU.

EndNote

Cankar Dal H (01 Nisan 2022) Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study. Journal of Cukurova Anesthesia and Surgical Sciences 5 1 33–42.

IEEE

[1]H. Cankar Dal, “Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study”, J Cukurova Anesth Surg, c. 5, sy 1, ss. 33–42, Nis. 2022, [çevrimiçi]. Erişim adresi: https://izlik.org/JA28UX86SU

ISNAD

Cankar Dal, Hayriye. “Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study”. Journal of Cukurova Anesthesia and Surgical Sciences 5/1 (01 Nisan 2022): 33-42. https://izlik.org/JA28UX86SU.

JAMA

1.Cankar Dal H. Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study. J Cukurova Anesth Surg. 2022;5:33–42.

MLA

Cankar Dal, Hayriye. “Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study”. Journal of Cukurova Anesthesia and Surgical Sciences, c. 5, sy 1, Nisan 2022, ss. 33-42, https://izlik.org/JA28UX86SU.

Vancouver

1.Hayriye Cankar Dal. Brain Death and Organ Donation During the COVID-19 Pandemic: A Retrospective Observational Study. J Cukurova Anesth Surg [Internet]. 01 Nisan 2022;5(1):33-42. Erişim adresi: https://izlik.org/JA28UX86SU