Yıl 2024,
, 124 - 127, 30.09.2024
Sıdıka Deniz Yalim
,
Selçuk Matyar
,
Hakan Yalım
Etik Beyan
Bu çalışmayı hazırlayan kişi olarak bütün bilgileri etik davranışlar ve akademik kurallar çerçevesinde makaleye eklediğimi, bana ait olmayan bilgiler için alınan kaynaklara doğru şekilde atıf yaptığımı ve makaleyi yazım kılavuzuna uygun şekilde hazırladığımı belirtirim.
Kaynakça
- 1.Romano F, Muscogiuri G, Benedetto E, et al. Vitamin D and sleep regulation:Is there a role for vitamin D? Curr Pharm Des 2020;26(21):2492-6.
https://doi.org/10.2174/1381612826666200310145935
- 2.Yavuz D, Mete T, Yavuz R, et al. D vitamini, kalsiyum & mineral metabolizması, D vitamininin iskelet dışı etkileri ve kronik böbrek yetmezliğinde nutrisyonel D vitamini kullanımı. Ankara Med J 2014;14(4):162-71.
https://doi.org/10.17098/amj.19812
- 3.American Academy of Sleep Medicine. International classification of sleep disorders.3rd edition. Darien IL: American Academy of Sleep Medicine 2014. https://doi.org/10.1378/chest.14-0970
- 4.Erden ES, Genc S, Motor S, et al. Investigation of serum bisphenol A, vitamin D and parathyroid hormone levels in patients with obstructive sleep apnea. Endocrine 2014;45(2):311-8.
https://doi.org/10.1007/s12020-013-0022-z
- 5.Bozkurt NC, Cakal E, Sahin M,et al. The relation of serum 25-hydroxyvitamin-D levels with severity of obstructive of obstructive sleep apnea and glucose metabolism abnormalities. Endocrine 2012;41(3):518-25.
https://doi.org/10.1007/s12020-012-9595-1
- 6.Salepci B, Caglayan B, Nahid P, et al. Vitamin D defiency in patients referred for evaluation for obstructive sleep apnea. Journal of Clinical Sleep Medicine 2017;13(4): 807-12.
https://doi.org/10.5664%2Fjcsm.6554
- 7.Mete T, Yalcin Y, Berker, et al. Obstructive sleep apnea syndrome and its association with vitamin D defiency. J Endocrinol Invest 2013;36(9):681-5. https://doi.org/10.3275/8923
- 8.Pazarli AC, Ekiz T, Inonu KH. Association between 25-hydroxy vitamin D and bone mineral density in people with obstructive sleep apnea syndrome. J Clin Densitom 2019;22(1):39-46.
https://doi.org/10.1016/j.jocd.2018.10.001
- 9.Kerley CP, Hutchinson K, Bolger K, et al. Serum vitamin D is significantly inversely associated with disease severity in caucasian adults with obstructive sleep apnea syndrome: a case control study. Sleep 2016;39(2):293-300.
https://doi.org/10.5665%2Fsleep.5430
- 10.Barcelo A,Esquinas C, Pierola J, et al. Vitamin D status and parathyroid hormone levels in patients with obstructive sleep apnea. Respiration 2013;86(4):295-301.
https://doi.org/10.1159/000342748
- 11.Piovezan RD, Hirotsu C, Feres MC, et al. Obstructive sleep apnea and objective short sleep duration are independantly associated with the risk of serum vitamin D deficiency. Plos One 2017;12:e0180901.
https://doi.org/10.1371/journal.pone.0180901
- 12.Archontogeorgis K, Nena E, Papanas N, et al. Vitamin D levels in middle aged patients with obstructive sleep apnoea syndrome. Curr Vasc Pharmacol 2018;16:289-297. https://doi.org/10.2174/1570161115666170529085708
- 13.Goswami U, Ensrud KE, Paudel ML, et al. Vitamin D concentrations and obstructive sleep apnea in a multicenter cohort of older males. Ann Am Thorac Soc 2016;13:712-718.
https://doi.org/10.1513/annalsats.201507-440oc
- 14.Yao N, Ma C, Dou Y, et al. Exploring the link between vitamin D defiency and obstructive sleep apnea: a comprehensive review. J Sleep Res 2024;e14166.
https://doi.org/10.1111/jsr.14166
- 15.Loh HH, Sukor N. Obstructive sleep apnea and vitamin D level: has the dust settled? Clin Respir J 2024;18:e13593.
https://doi.org/10.1111/crj.13593
The Serum 25(OH) Vitamin D, Calcium, and Parathyroid Hormone Levels of The Patients With The Obstructive Sleep Apnea Syndrome
Yıl 2024,
, 124 - 127, 30.09.2024
Sıdıka Deniz Yalim
,
Selçuk Matyar
,
Hakan Yalım
Öz
Background: Although there is evidence linking vitamin D to many neurochemical processes involved in sleep, the association between the obstructive sleep apnea and vitamin D, calcium and parathyroid hormone is still unknown, as clinical research have shown inconsistent findings. In this study, we aimed to examine the hypothesis that if there is any relationship between obstructive sleep apnea and serum vitamin D, calcium and parathyroid hormone levels in order to manage treatment.
Methods: 56 patients (32 male, 24 female) admitted to the University of Health Sciences Adana City Training and Research Hospital otorhinolaryngology clinic between January 1st, 2022 and January 1st 2023 without any acute and chronic disease were included in the study. The range of participants was 18-70. In this study we examined the serum vitamin D, calcium and parathyroid hormone levels of 32 obstructive sleep apnea patients and compared their serum vitamin D, calcium and parathyroid hormone levels with the serum vitamin D, calcium and parathyroid hormone levels of 24 normal patients in the control group.
Results: When the serum vitamin D, calcium and parathyroid hormone levels of obstructive sleep apnea patients and serum vitamin D, calcium and parathyroid hormone levels of normal patients were compared we did not find a statistically significant difference which may be due to our patient density.
Conclusion: Vitamin D, calcium and parathyroid hormone levels are not likely related to the presence or absence of obstructive sleep apnea. More intervention studies are needed to better clarify the relation between the obstructive sleep apnea and vitamin D, calcium and parathyroid hormone.
Etik Beyan
As the person who prepared this study, I state that I have added all the information to the article within the framework of ethical behavior and academic rules, that I have correctly cited the sources for information that does not belong to me, and that I have prepared the article in accordance with the writing guide.
Kaynakça
- 1.Romano F, Muscogiuri G, Benedetto E, et al. Vitamin D and sleep regulation:Is there a role for vitamin D? Curr Pharm Des 2020;26(21):2492-6.
https://doi.org/10.2174/1381612826666200310145935
- 2.Yavuz D, Mete T, Yavuz R, et al. D vitamini, kalsiyum & mineral metabolizması, D vitamininin iskelet dışı etkileri ve kronik böbrek yetmezliğinde nutrisyonel D vitamini kullanımı. Ankara Med J 2014;14(4):162-71.
https://doi.org/10.17098/amj.19812
- 3.American Academy of Sleep Medicine. International classification of sleep disorders.3rd edition. Darien IL: American Academy of Sleep Medicine 2014. https://doi.org/10.1378/chest.14-0970
- 4.Erden ES, Genc S, Motor S, et al. Investigation of serum bisphenol A, vitamin D and parathyroid hormone levels in patients with obstructive sleep apnea. Endocrine 2014;45(2):311-8.
https://doi.org/10.1007/s12020-013-0022-z
- 5.Bozkurt NC, Cakal E, Sahin M,et al. The relation of serum 25-hydroxyvitamin-D levels with severity of obstructive of obstructive sleep apnea and glucose metabolism abnormalities. Endocrine 2012;41(3):518-25.
https://doi.org/10.1007/s12020-012-9595-1
- 6.Salepci B, Caglayan B, Nahid P, et al. Vitamin D defiency in patients referred for evaluation for obstructive sleep apnea. Journal of Clinical Sleep Medicine 2017;13(4): 807-12.
https://doi.org/10.5664%2Fjcsm.6554
- 7.Mete T, Yalcin Y, Berker, et al. Obstructive sleep apnea syndrome and its association with vitamin D defiency. J Endocrinol Invest 2013;36(9):681-5. https://doi.org/10.3275/8923
- 8.Pazarli AC, Ekiz T, Inonu KH. Association between 25-hydroxy vitamin D and bone mineral density in people with obstructive sleep apnea syndrome. J Clin Densitom 2019;22(1):39-46.
https://doi.org/10.1016/j.jocd.2018.10.001
- 9.Kerley CP, Hutchinson K, Bolger K, et al. Serum vitamin D is significantly inversely associated with disease severity in caucasian adults with obstructive sleep apnea syndrome: a case control study. Sleep 2016;39(2):293-300.
https://doi.org/10.5665%2Fsleep.5430
- 10.Barcelo A,Esquinas C, Pierola J, et al. Vitamin D status and parathyroid hormone levels in patients with obstructive sleep apnea. Respiration 2013;86(4):295-301.
https://doi.org/10.1159/000342748
- 11.Piovezan RD, Hirotsu C, Feres MC, et al. Obstructive sleep apnea and objective short sleep duration are independantly associated with the risk of serum vitamin D deficiency. Plos One 2017;12:e0180901.
https://doi.org/10.1371/journal.pone.0180901
- 12.Archontogeorgis K, Nena E, Papanas N, et al. Vitamin D levels in middle aged patients with obstructive sleep apnoea syndrome. Curr Vasc Pharmacol 2018;16:289-297. https://doi.org/10.2174/1570161115666170529085708
- 13.Goswami U, Ensrud KE, Paudel ML, et al. Vitamin D concentrations and obstructive sleep apnea in a multicenter cohort of older males. Ann Am Thorac Soc 2016;13:712-718.
https://doi.org/10.1513/annalsats.201507-440oc
- 14.Yao N, Ma C, Dou Y, et al. Exploring the link between vitamin D defiency and obstructive sleep apnea: a comprehensive review. J Sleep Res 2024;e14166.
https://doi.org/10.1111/jsr.14166
- 15.Loh HH, Sukor N. Obstructive sleep apnea and vitamin D level: has the dust settled? Clin Respir J 2024;18:e13593.
https://doi.org/10.1111/crj.13593