Subjektif Göz Şikayetleri Olan Hastalarda Kornea Analizi; Yeni Tanılı Prediyabetik Hastalar

Öz

Giriş: Görme kalitesinde azalma benzeri subjektif şikayetler ile başvuran prediyabetik hastalarda olası korneal değişikliklerinin saptanması amaçlanmıştır. Materyaller ve Yöntemler: Çalışmaya subjektif görme şikayetleri olan, herhangi bir optik sinir ve retina patolojisi saptanmayan, emetropik, travma öyküsü olmayan yeni tanılı 56 prediyabetik hasta ve 70 sağlıklı katılımcı dahil edilmiştir. Tüm hastaların detaylı ön segment ve muayeneleri sonrasında Scheimpflug Sirius® cihazı ile korneal topografi değerlendirilmesi yapılmış ve HbA1c değerleri ile karşılaştırılmıştır. Results: Prediyabetik grupta yer alan hastaların yaş ortalaması 57,23 ± 8.1 yıl iken, kontrol grubundaki hastaların 60,58±6.74 yıl idi. (p>0,05). CCT değerleri prediyabetik grupta 550,00 µ ±45,00, kontrol grubunda ise 553,00 µ± 38 olarak saptandı. MCT prediyabetik grupta 518,00±41,00 µ, kontrol grubunda 533,00±33,00 µ olarak saptandı. Korneal dasitometri değerleri prediyabetik grupta 23,47±2,36 GSU iken kontrol grubunda ise 21,76±3,22 GSU olarak bulundu (p=<0.001). Grupların ortalama HbAc1 değerleri prediyabetik grupta 6,30±1,10 kontrol grubunda ise 5,20±0,20 idi. Ortalama kan şekeri değerleri ise prediyabetik grupta 109±26 ve kontrol grubunda 91±8 olarak saptandı. Korneanın refraktif değerleri ise sırasıyla prediyabetik grupta K1 değerleri 43,16 D±1,36 kontrol grubunda 42,38 D±1,38, K2 değerleri 44,15 D±1,50 kontrol grubunda 43,66 D±1,51 idi. HbA1c değerleri artıkça korneal dansitometri değerlerinin arttığı görülürken yapılan istatistiksel değerlendirmede iki değer arasında pozitif yönde korelasyon saptandı (r=.279**, p=0,002) Sonuç: Prediyabetik durumun korneal dansitometri üzerindeki etkileri ve korneanın kalınlığı için olumsuz bir faktör olarak kabul edilmelidir. Subjektif görme şikayeti olan ve rekraftif değişiklik saptanmayan kişilerde prediyabetik durum b ve buna bağlı korneal değişiklikler olabilme ihtimali göz önünde bulundurulmalıdır. Keywords: Prediyabet, Korneal Dansitometri, HbA1c

Anahtar Kelimeler

• Prediyabet
• Korneal Dansitometri
• HbA1c

Corneal Analysis in Patients Presenting with Subjective Eye Complaints; Newly Diagnosed Prediabetic Patients

Abstract

Introduction: Subjective symptoms such as decreased visual quality The aim of this study was to detect possible corneal changes in prediabetic patients presenting with complaints . Materials and Methods: The study included 56 newly diagnosed prediabetic patients with subjective visual complaints, no optic nerve and retina pathology, emmetropic , no history of trauma , and 70 healthy participants. After detailed anterior segment and Corneal with Sirius ® device Topography was evaluated and compared with HbA1c values. Results : The mean age of the patients in the prediabetic group was 57.23 ± 8.1 years, while the mean age of the patients in the control group was 60.58±6.74 years (p>0.05). CCT values were 550.00 µ ± 45.00 in the prediabetic group and 553.00 µ± 38 in the control group. MCT was 518.00± 41.00 µ in the prediabetic group and 533.00± 33.00 µ in the control group. Corneal The mean HbAc1 values of the groups were 6.30 ±1.10 in the prediabetic group and 5.20±0.20 in the control group. The mean blood sugar values were 109±26 in the prediabetic group and 91±8 in the control group. The refractive values of the cornea were 43.16 D±1.36 in the prediabetic group, 42.38 D±1.38 in the control group, and 44.15 D±1.50 in the control group, and 43.66 D±1.51 in the control group, respectively . As the HbA1c values increased, the corneal While it was observed that the densitometry values increased, a positive correlation was found between the two values in the statistical evaluation (r=.279**, p=0.002). Conclusion: Prediabetic status is associated with corneal effects on densitometry and should be considered as a negative factor for the thickness of the cornea. In individuals with subjective visual complaints and no refractive changes, the possibility of prediabetic status b and related corneal changes should be taken into consideration.

Keywords

• Prediabetes
• Corneal Densitometry
• HbA1c

Kaynakça

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