Predictive Value of Preoperative Neutrophil-to-Lymphocyte Ratio on Postoperative Complications in Valve Surgery Patients

Abstract

Aim: It aims to retrospectively evaluate the relationship between preoperative neutrophil-lymphocyte ratio (NLR) values and the incidence of postoperative complications in patients undergoing heart valve replacement. Material and Methods: This retrospective cohort study examined the data of 412 adult patients undergoing elective aortic and/or mitral valve replacement. NLR was calculated from blood samples 24 hours before surgery. Patients were divided into two groups based on NLR values: Group 1: NLR < 3.0 and Group 2: NLR ≥ 3.0. Results: According to preoperative NLR values, 268 patients (65%) were in Group 1 and 144 patients (35%) were in Group 2. Significantly higher rates of postoperative atrial fibrillation (PoAF), renal dysfunction, prolonged mechanical ventilation, and infectious complications were observed in Group 2 compared to Group 1. Conclusion: It demonstrates that preoperative NLR may be a simple and effective tool for risk stratification in patients undergoing valve surgery.

Keywords

• Heart valve surgery
• preoperative neutrophil-lymphocyte ratio
• postoperative complications.

Kapak Cerrahisi Hastalarında Ameliyat Öncesi Nötrofil-Lenfosit Oranının Ameliyat Sonrası Komplikasyonlar Üzerindeki Tahmini Değeri

Öz

Giriş: Kalp kapak replasmanı geçiren hastalarda preoperatif nötrofil-lenfosit oranı (NLR) değerleri ile postoperatif komplikasyon insidansı arasındaki ilişkiyi retrospektif olarak değerlendirmeyi amaçlamaktadır. Gereç ve Yöntemler: Bu retrospektif kohort çalışmada elektif aort ve/veya mitral kapak replasmanı geçiren toplam 412 yetişkin hastanın verileri incelendi. NLR, ameliyattan 24 saat önceki kan örneklerinden hesaplandı. Hastalar NLR değerlerine göre iki gruba ayrıldı: Grup 1: NLR < 3,0 ve Grup 2: NLR ≥ 3,0. Sonuç: Preoperatif NLR değerlerine göre 268 hasta (%65) Grup 1'de, 144 hasta (%35) Grup 2'de yer aldı. Grup 2'de, Grup 1'e kıyasla anlamlı derecede daha yüksek oranda postoperatif atriyal fibrilasyon (PoAF), böbrek fonksiyon bozukluğu, uzun süreli mekanik ventilasyon ve enfeksiyöz komplikasyonlar görüldü. Tartışma: Preoperatif NLR'nin kapak cerrahisi geçiren hastalarda risk sınıflandırması için basit ve etkili bir araç olabileceğini göstermektedir.

Anahtar Kelimeler

• Kalp kapak cerrahisi
• preoperative nötrofil-lenfosit oranı
• postoperatif komplikasyon.

Kaynakça

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