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Perioperative Hypothermia: Mechanism, Risk Factors and New Protocols in Prevention and Treatment

Yıl 2026, Cilt: 9 Sayı: 1, 185 - 191, 17.03.2026
https://izlik.org/JA78PK73WS

Öz

ABSTRACT Introduction: Perioperative hypothermia (POH) is defined as a core temperature drop below 36°C during anaesthesia and surgery and leads to coagulation disorders, increased transfusion requirements, delayed wound healing and an elevated infection risk, prolonged hospitalisation and increased costs. It is therefore vital to maintain normal body temperature both before and after surgery in order to ensure optimal surgical outcomes, as well as patient safety and satisfaction. Methods: In order to ensure optimal outcomes, it is imperative that prevention and management of POH should include preoperative risk assessments, monitoring of perioperative body temperature, control of environmental temperature, and the development of comprehensive warming protocols and checklists. Conclusion: The present review examines recent studies and technological advancements regarding risk factors and prevention strategies for POH, with the aim of providing a practical guide for clinicians. Keywords: Perioperative hypothermia, general anaesthesia, neuroaxial blocks, normothermia

Etik Beyan

An ethics committee decision is not required.

Destekleyen Kurum

none

Teşekkür

none

Kaynakça

  • Nakamura K. Central circuitries for body temperature regulation and fever. Am J Physiol Regul Integr Comp Physiol. 2011;301(5):R1207-R1228. Crossref
  • Romanovsky AA. Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system. Am J Physiol Regul Integr Comp Physiol. 2007;292(1):R37-R46. Crossref
  • Charkoudian N. Skin blood flow in adult human thermoregulation: how it works, when it does not, and why. Mayo Clin Proc. 2003;78(5):603-612. Crossref
  • De Witte J, Sessler DI. Perioperative shivering: physiology and pharmacology. Anesthesiology. 2002;96(2):467-484. Crossref
  • Hales JR, Jessen C, Fawcett AA, King RB. Skin AVA and capillary dilatation and constriction induced by local skin heating. Pflugers Arch. 1985;404(3):203-207. Crossref
  • Díaz M, Becker DE. Thermoregulation: physiological and clinical considerations during sedation and general anesthesia. Anesth Prog. 2010;57(1):25-32. Crossref
  • Bindu B, Bindra A, Rath G. Temperature management under general anesthesia: compulsion or option. J Anaesthesiol Clin Pharmacol. 2017;33(3):306-316. Crossref
  • Buggy DJ, Crossley AW. Thermoregulation, mild perioperative hypothermia and postanaesthetic shivering. Br J Anaesth. 2000;84(5):615-628. Crossref
  • Tews D, Wabitsch M. Brown adipose tissue in children and its metabolic function. Horm Res Paediatr. 2022;95(2):104-111. Crossref
  • Akhtar Z, Hesler B, Fiffick A, Mascha E, Sessler D, Kurz A, et al. A randomized trial of prewarming on patient satisfaction and thermal comfort in outpatient surgery. J Clin Anesth. 2016;33:376-385. Crossref
  • Diamond A, Prasad D, Abbott D. One size does not fit all: assuming the same normal body temperature for everyone is not justified. PLoS One. 2021;16(2):e0245257. Crossref
  • Lee Y, Kim K. Optimal application of forced air warming to prevent peri-operative hypothermia during abdominal surgery: a systematic review and meta-analysis. Int J Environ Res Public Health. 2021;18(5):2517. Crossref
  • Zhang B, Zhou H, Wang X, Zheng Y, Hu L. Advances in the multimodal management of perioperative hypothermia: approaches from traditional Chinese and Western medicine. Perioper Med (Lond). 2024;13(1):107. Crossref
  • Billeter AT, Hohmann SF, Druen D, Cannon R, Polk Jr H. Unintentional perioperative hypothermia is associated with severe complications and high mortality in elective operations. Surgery. 2014;156(5):1245-1252. Crossref
  • Mroczek TJ, Prodromidis AD, Pearce A, Malik RA, Charalambous CP. Perioperative Hypothermia Is Associated With Increased 30-Day Mortality in Hip Fracture Patients in the United Kingdom: A Systematic Review and Meta-analysis. J Orthop Trauma. 2022;36(7):343-348. Crossref
  • Xu H, Wang Z, Guan X, Lu Y, Malone DC, Salmon JW, et al. Safety of intraoperative hypothermia for patients: meta-analyses of randomized controlled trials and observational studies. BMC Anesthesiol. 2020;20(1):202. Crossref
  • Bu N, Zhao E, Gao Y, Zhao S, Bo W, Kong Z, et al. Association between perioperative hypothermia and surgical site infection: A meta-analysis. Medicine (Baltimore). 2019;98(6):e14392. Crossref
  • Chen R, Du Y, Chen L, Bai Y, Zhang Y, Yu T, et al. The impact of perioperative hypothermia on surgical site infection risk: a meta-analysis. BMC Anesthesiol. 2025;25(1):443. Crossref
  • Yi J, Zhan L, Lei Y, Xu S, Si Y, Li S, et al. Establishment and validation of a prediction equation to estimate risk of intraoperative hypothermia in patients receiving general anesthesia. Sci Rep. 2017;7(1):13927. Crossref
  • Torossian A, Bräuer A, Höcker J, Bein B, Wulf H, Horn EP. Preventing inadvertent perioperative hypothermia. Dtsch Arztebl Int. 2015;112(10):166-172. Crossref
  • Uçak A, Çatal AT, Karadağ E, Cebeci F. The effect of prewarming on perioperative hypothermia: A systematic review and meta-analysis of randomized controlled studies. J Perianesth Nurs. 2024;39(4):611-623. Crossref
  • de Bernardis RCG, Siaulys MM, Vieira JE, Mathias LAST. Perioperative warming with a thermal gown prevents maternal temperature loss during elective cesarean section. A randomized clinical trial. Braz J Anesthesiol. 2016;66(5):451-455. Crossref
  • Giuliano KK, Hendricks J. Inadvertent Perioperative Hypothermia: current nursing knowledge. AORN J. 2017;105(5):453-463. Crossref
  • Yang L, Huang C, Zhou Z, Wen Z, Zhang G, Liu K, et al. Risk factors for hypothermia in patients under general anesthesia: is there a drawback of laminar airflow operating rooms? A prospective cohort study. Int J Surg. 2015;21:14-17. Crossref
  • Sessler DI. How three linked clinical observations led to an understanding of perioperative heat balance: a personal reflection on the scientific process. J Clin Anesth. 2024;96:111496. Crossref
  • Riley C, Andrzejowski J. Inadvertent perioperative hypothermia. BJA Educ. 2018;18(8):227-233. Crossref
  • Matsukawa T, Sessler DI, Sessler AM, Schroeder M, Ozaki M, Kurz A, et al. Heat flow and distribution during induction of general anesthesia. Anesthesiology. 1995;82(3):662-673. Crossref
  • Xiong J, Kurz A, Sessler DI, Plattner O, Christensen R, Dechert M, et al. Isoflurane produces marked and non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology. 1996;85(2):240-245. Crossref
  • Matsukawa T, Kurz A, Sessler DI, Bjorksten AR, Merrifield B, Cheng C. Propofol linearly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;82(5):1169-1180. Crossref
  • Annadata RS, Sessler DI, Tayefeh F, Kurz A, Dechert M. Desflurane slightly increases the sweating threshold, but produces marked, non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83(6):1205-1211. Crossref
  • Kurz A, Go JC, Sessler DI, Kaer K, Larson M, Bjorksten AR. Alfentanil slightly increases the sweating threshold and markedly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83(2):293-299. Crossref
  • Lai LL, See MH, Rampal S, Ng KS, Chan L. Significant factors influencing inadvertent hypothermia in pediatric anesthesia. J Clin Monit Comput. 2019;33(6):1105-1112. Crossref
  • Kurz A, Sessler DI, Schroeder M, Kurz M. Thermoregulatory response thresholds during spinal anesthesia. Anesth Analg. 1993;77(4):721-726. Crossref
  • Leslie K, Sessler DI. Reduction in the shivering threshold is proportional to spinal block height. Anesthesiology. 1996;84(6):1327-1331. Crossref
  • Kim JS, Ikeda T, Sessler DI, Turakhia M, Jeffrey R. Epidural anesthesia reduces the gain and maximum intensity of shivering. Anesthesiology. 1998;88(4):851-857. Crossref
  • Joris J, Ozaki M, Sessler DI, Hardy AF, Lamy M, McGuire J, et al. Epidural anesthesia impairs both central and peripheral thermoregulatory control during general anesthesia. Anesthesiology. 1994;80(2):268-277. Crossref
  • Sessler DI. Perioperative thermoregulation and heat balance. Lancet. 2016;387(10038):2655-2664. Crossref
  • Cho SA, Chang M, Lee SJ, Sung TY, Cho CK. Prewarming for prevention of hypothermia in older patients undergoing hand surgery under brachial plexus block. Ann Geriatr Med Res. 2022;26(2):175-182. Crossref
  • Hynson J, Sessler DI. Intraoperative warming therapies: a comparison of three devices. J Clin Anesth. 1992;4(3):194-199. Crossref
  • Bickler P, Sessler DI. Efficiency of airway heat and moisture exchangers in anesthetized humans. Anesth Analg. 1990;71(4):415-418. Crossref
  • Giesbrecht GG, Ducharme MB, McGuire JP. Comparison of forced-air patient warming systems for perioperative use. Anesthesiology. 1994;80(3):671-679. Crossref
  • Ozaki M, Kurz A, Sessler DI, Lenhardt R, Schroeder M, Moayeri A, et al. Thermoregulatory thresholds during spinal and epidural anesthesia. Anesthesiology. 1994;81(2):282-288. Crossref
  • Brück K, Zeisberger E. Adaptive changes in thermoregulation and their neuropharmacological basis. Pharmacol Ther. 1987;35(1-2):163-215. Crossref
  • Recio-Pérez J, Miró Murillo M, Martin Mesa M, García JS, Santonocito C, Sanfilippo F, et al. Effect of prewarming on perioperative hypothermia in patients undergoing loco-Regional or general anesthesia: a randomized clinical trial. Medicina (Kaunas). 2023;59(12):2082. Crossref
  • Sessler DI. Perioperative Temperature Monitoring. Anesthesiology. 2021;134(1):111-118. Crossref
  • Bock M, Hohlfeld U, Von Engeln K, Meier PA, Motsch J, Tasman AJ. The accuracy of a new infrared ear thermometer in patients undergoing cardiac surgery. Can J Anaesth. 2005;52(10):1083-1087. Crossref
  • Boisson M, Alaux A, Kerforne T, Mimoz O, Debaene B, Dahyot-Fizelier C, et al. Intra-operative cutaneous temperature monitoring with zero-heat-flux technique (3M SpotOn) in comparison with oesophageal and arterial temperature: a prospective observational study. Eur J Anaesthesiol. 2018;35(11):825-830. Crossref
  • Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. Crossref
  • Horosz B, Malec-Milewska M. Methods to prevent intraoperative hypothermia. Anaesthesiol Intensive Ther. 2014;46(2):96-100. Crossref
  • Perlman R, Callum J, Laflamme C, Tien H, Nascimento B, Beckett A, et al. A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients. Crit Care. 2016;20(1):107. Crossref
  • Cobb B, Cho Y, Hilton G, Ting V, Carvalho B. Active warming utilizing combined IV fluid and forced-air warming decreases hypothermia and improves maternal comfort during cesarean delivery: a randomized control trial. Anesth Analg. 2016;122(5):1490-1497. Crossref
  • Min S, Yoon S, Yoon S, Bahk J, Seo J. Randomised trial comparing forced-air warming to the upper or lower body to prevent hypothermia during thoracoscopic surgery in the lateral decubitus position. Br J Anaesth. 2018;120(3):555-562. Crossref
  • Thiel B, Mooijer B, Kolff-Gart A, Kerklaan B, Poolman R, de Haan P, et al. Is preoperative forced-air warming effective in the prevention of hypothermia in orthopedic surgical patients? A randomized controlled trial. J Clin Anesth. 2020;61:109633. Crossref
  • Van Duren A. Perioperative prewarming: heat transfer and physiology. AORN J. 2022;115(5):407-422. Crossref
  • Madrid E, Urrútia G, Figuls MR, Pardo-Hernandez H, Campos JM, Paniagua P, et al. Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. Cochrane Database Syst Rev. 2016;4(4):CD009016. Crossref
  • Horn EP, Bein B, Böhm R, Steinfath M, Sahili N, Höcker J. The effect of short time periods of pre-operative warming in the prevention of peri-operative hypothermia. Anaesthesia. 2012;67(6):612-617. Crossref
  • Sultan P, Habib A, Cho Y, Carvalho B. The Effect of patient warming during Caesarean delivery on maternal and neonatal outcomes: a meta-analysis. Br J Anaesth. 2015;115(4):500-510. Crossref
  • Alparslan V, Kus A, Hosten T, Ertargin M, Ozdamar D, Toker K, Solak M. Comparison of forced-air warming systems in prevention of intraoperative hypothermia. J Clin Monit Comput. 2018;32(2):343-349. Crossref
  • Wang X, Su W, Yuqing M, Ge H, Chang W, Ma G, et al. Effectiveness of Forced-air Warming in Preventing Hypothermia During Laparoscopic Surgery: A RCT Meta-analysis. J Perianesth Nurs. 2025:S1089-9472(25)00172-8. Crossref
  • Lee Y, Kim K. Optimal application of forced air warming to prevent peri-operative hypothermia during abdominal surgery: a systematic review and meta-analysis. Int J Environ Res Public Health. 2021;18(5):2517. Crossref
  • Chen YC, Cherng YG, Romadlon DS, Chang KM, Huang CJ, Tsai PS, et al. Comparative effects of warming systems applied to different parts of the body on hypothermia in adults undergoing abdominal surgery: A systematic review and network meta-analysis of randomized controlled trials. J Clin Anesth. 2023;89:111190. Crossref
  • Fossum S, Hays J, Henson MM. A comparison study on the effects of prewarming patients in the outpatient surgery setting. J Perianesth Nurs. 2001;16(3):187-194. Crossref
  • Ji N, Wang J, Li X, Shang Y. Strategies for perioperative hypothermia management: advances in warming techniques and clinical implications: a narrative review. BMC Surg. 2024;24(1):425. Crossref
  • Roxby D, Sobieraj-Teague M, von Wielligh J, Sinha R, Kuss B, Smith AL, et al. Warming blood prior to transfusion using latent heat. Emerg Med Australas. 2020;32(4):604-610. Crossref
  • Munday J, Hines S, Wallace K, Chang AM, Gibbons K, Yates P. A systematic review of the effectiveness of warming interventions for women undergoing cesarean section. Worldviews Evid Based Nurs. 2014;11(6):383-393. Crossref
  • Campbell G, Alderson P, Smith AF, Warttig S. Warming of intravenous and irrigation fluids for preventing inadvertent perioperative hypothermia. Cochrane Database Syst Rev. 2015;2015(4):CD009891. Crossref
  • De Mattia AL, Barbosa MH, de Freitas Filho JP, Rocha Ade M, Pereira NH. Warmed intravenous infusion for controlling intraoperative hypothermia. Rev Lat Am Enfermagem. 2013;21(3):803-810. Crossref
  • Tubog TD, Kane TD, Ericksen AM. Combined Forced Air Warming and Warm Intravenous Fluid Strategy for Perioperative Hypothermia in Cesarean Delivery: A Systematic Review and Meta-Analysis. J Perianesth Nurs. 2023;38(1):21-32. Crossref
  • Balayssac D, Pereira B, Bazin JE, Le Roy B, Pezet D, Gagniere J. Warmed and humidified carbon dioxide for abdominal laparoscopic surgery: metaanalysis of the current literature. Surg Endosc. 2017;31(1):1-12. Crossref
  • Birch DW, Dang JT, Switzer NJ, Manouchehri N, Shi X, Hadi G, et al. Heated insufflation with or without humidification for laparoscopic abdominal surgery. Cochrane Database Syst Rev. 2016;10(10):CD007821. Crossref
  • Noll E, Diemunsch S, Pottecher J, Rameaux JP, Diana M, Sauleau E, et al. Prevention of laparoscopic surgery induced hypothermia with warmed humidified insufflation: is the experimental combination of a warming blanket synergistic? PLoS One. 2018;13(7):e0199369. Crossref
  • Wittenborn J, Mathei D, van Waesberghe J, Zeppernick F, Zeppernick M, Tchaikovski S, et al. The effect of warm and humidified gas insufflation in gynecological laparoscopy on maintenance of body temperature: a prospective randomized controlled multi-arm trial. Arch Gynecol Obstet. 2022;306(3):753-767. Crossref
  • Miyazaki R, Hoka S, Yamaura K. Visceral fat, but not subcutaneous fat, is associated with lower core temperature during laparoscopic surgery. PLoS One. 2019;14(6):e0218281. Crossref
  • Chen Y, Wang Y, Zhang YL, Zhang JJ, Hua Z, Li ZJ, et al. A prediction model for estimating risk of intraoperative hypothermia in patients undergoing general anesthesia: a prospective multicenter study. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2022;44(6):1028-1032. Crossref

PERİOPERATİF HİPOTERMİ: MEKANİZMA, RİSK FAKTÖRLERİ VE ÖNLEME VE TEDAVİDE YENİ PROTOKOLLER

Yıl 2026, Cilt: 9 Sayı: 1, 185 - 191, 17.03.2026
https://izlik.org/JA78PK73WS

Öz

ÖZET Giriş: Perioperatif hipotermi (POH), anestezi ve ameliyat sırasında vücut çekirdek sıcaklığının 36°C'nin altına düşmesi olarak tanımlanır ve pıhtılaşma bozukluklarına, artan transfüzyon ihtiyacına, yara iyileşmesinin gecikmesine ve enfeksiyon riskinin artmasına, hastanede kalış süresinin uzamasına ve maliyetlerin artmasına yol açar. Bu nedenle, optimal cerrahi sonuçların yanı sıra hasta güvenliği ve memnuniyetini sağlamak için hem ameliyat öncesi hem de sonrasında normal vücut sıcaklığının korunması hayati önem taşır. Yöntem: Optimal sonuçları sağlamak için, POH'nin önlenmesi ve yönetimi, ameliyat öncesi risk değerlendirmelerini, perioperatif vücut sıcaklığının izlenmesini, çevresel sıcaklığın kontrolünü ve kapsamlı ısıtma protokolleri ve kontrol listelerinin geliştirilmesini içermelidir. Sonuç: Bu derleme, klinisyenler için pratik bir kılavuz sağlamayı amaçlayarak, POH için risk faktörleri ve önleme stratejileri ile ilgili son çalışmaları ve teknolojik gelişmeleri incelemektedir. Anahtar Kelimeler: Perioperatif hipotermi, genel anestezi, nöroaksiyel blok, normotermi

Etik Beyan

Etik kurul kararına gerek yoktur.

Destekleyen Kurum

none

Teşekkür

none

Kaynakça

  • Nakamura K. Central circuitries for body temperature regulation and fever. Am J Physiol Regul Integr Comp Physiol. 2011;301(5):R1207-R1228. Crossref
  • Romanovsky AA. Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system. Am J Physiol Regul Integr Comp Physiol. 2007;292(1):R37-R46. Crossref
  • Charkoudian N. Skin blood flow in adult human thermoregulation: how it works, when it does not, and why. Mayo Clin Proc. 2003;78(5):603-612. Crossref
  • De Witte J, Sessler DI. Perioperative shivering: physiology and pharmacology. Anesthesiology. 2002;96(2):467-484. Crossref
  • Hales JR, Jessen C, Fawcett AA, King RB. Skin AVA and capillary dilatation and constriction induced by local skin heating. Pflugers Arch. 1985;404(3):203-207. Crossref
  • Díaz M, Becker DE. Thermoregulation: physiological and clinical considerations during sedation and general anesthesia. Anesth Prog. 2010;57(1):25-32. Crossref
  • Bindu B, Bindra A, Rath G. Temperature management under general anesthesia: compulsion or option. J Anaesthesiol Clin Pharmacol. 2017;33(3):306-316. Crossref
  • Buggy DJ, Crossley AW. Thermoregulation, mild perioperative hypothermia and postanaesthetic shivering. Br J Anaesth. 2000;84(5):615-628. Crossref
  • Tews D, Wabitsch M. Brown adipose tissue in children and its metabolic function. Horm Res Paediatr. 2022;95(2):104-111. Crossref
  • Akhtar Z, Hesler B, Fiffick A, Mascha E, Sessler D, Kurz A, et al. A randomized trial of prewarming on patient satisfaction and thermal comfort in outpatient surgery. J Clin Anesth. 2016;33:376-385. Crossref
  • Diamond A, Prasad D, Abbott D. One size does not fit all: assuming the same normal body temperature for everyone is not justified. PLoS One. 2021;16(2):e0245257. Crossref
  • Lee Y, Kim K. Optimal application of forced air warming to prevent peri-operative hypothermia during abdominal surgery: a systematic review and meta-analysis. Int J Environ Res Public Health. 2021;18(5):2517. Crossref
  • Zhang B, Zhou H, Wang X, Zheng Y, Hu L. Advances in the multimodal management of perioperative hypothermia: approaches from traditional Chinese and Western medicine. Perioper Med (Lond). 2024;13(1):107. Crossref
  • Billeter AT, Hohmann SF, Druen D, Cannon R, Polk Jr H. Unintentional perioperative hypothermia is associated with severe complications and high mortality in elective operations. Surgery. 2014;156(5):1245-1252. Crossref
  • Mroczek TJ, Prodromidis AD, Pearce A, Malik RA, Charalambous CP. Perioperative Hypothermia Is Associated With Increased 30-Day Mortality in Hip Fracture Patients in the United Kingdom: A Systematic Review and Meta-analysis. J Orthop Trauma. 2022;36(7):343-348. Crossref
  • Xu H, Wang Z, Guan X, Lu Y, Malone DC, Salmon JW, et al. Safety of intraoperative hypothermia for patients: meta-analyses of randomized controlled trials and observational studies. BMC Anesthesiol. 2020;20(1):202. Crossref
  • Bu N, Zhao E, Gao Y, Zhao S, Bo W, Kong Z, et al. Association between perioperative hypothermia and surgical site infection: A meta-analysis. Medicine (Baltimore). 2019;98(6):e14392. Crossref
  • Chen R, Du Y, Chen L, Bai Y, Zhang Y, Yu T, et al. The impact of perioperative hypothermia on surgical site infection risk: a meta-analysis. BMC Anesthesiol. 2025;25(1):443. Crossref
  • Yi J, Zhan L, Lei Y, Xu S, Si Y, Li S, et al. Establishment and validation of a prediction equation to estimate risk of intraoperative hypothermia in patients receiving general anesthesia. Sci Rep. 2017;7(1):13927. Crossref
  • Torossian A, Bräuer A, Höcker J, Bein B, Wulf H, Horn EP. Preventing inadvertent perioperative hypothermia. Dtsch Arztebl Int. 2015;112(10):166-172. Crossref
  • Uçak A, Çatal AT, Karadağ E, Cebeci F. The effect of prewarming on perioperative hypothermia: A systematic review and meta-analysis of randomized controlled studies. J Perianesth Nurs. 2024;39(4):611-623. Crossref
  • de Bernardis RCG, Siaulys MM, Vieira JE, Mathias LAST. Perioperative warming with a thermal gown prevents maternal temperature loss during elective cesarean section. A randomized clinical trial. Braz J Anesthesiol. 2016;66(5):451-455. Crossref
  • Giuliano KK, Hendricks J. Inadvertent Perioperative Hypothermia: current nursing knowledge. AORN J. 2017;105(5):453-463. Crossref
  • Yang L, Huang C, Zhou Z, Wen Z, Zhang G, Liu K, et al. Risk factors for hypothermia in patients under general anesthesia: is there a drawback of laminar airflow operating rooms? A prospective cohort study. Int J Surg. 2015;21:14-17. Crossref
  • Sessler DI. How three linked clinical observations led to an understanding of perioperative heat balance: a personal reflection on the scientific process. J Clin Anesth. 2024;96:111496. Crossref
  • Riley C, Andrzejowski J. Inadvertent perioperative hypothermia. BJA Educ. 2018;18(8):227-233. Crossref
  • Matsukawa T, Sessler DI, Sessler AM, Schroeder M, Ozaki M, Kurz A, et al. Heat flow and distribution during induction of general anesthesia. Anesthesiology. 1995;82(3):662-673. Crossref
  • Xiong J, Kurz A, Sessler DI, Plattner O, Christensen R, Dechert M, et al. Isoflurane produces marked and non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology. 1996;85(2):240-245. Crossref
  • Matsukawa T, Kurz A, Sessler DI, Bjorksten AR, Merrifield B, Cheng C. Propofol linearly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;82(5):1169-1180. Crossref
  • Annadata RS, Sessler DI, Tayefeh F, Kurz A, Dechert M. Desflurane slightly increases the sweating threshold, but produces marked, non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83(6):1205-1211. Crossref
  • Kurz A, Go JC, Sessler DI, Kaer K, Larson M, Bjorksten AR. Alfentanil slightly increases the sweating threshold and markedly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83(2):293-299. Crossref
  • Lai LL, See MH, Rampal S, Ng KS, Chan L. Significant factors influencing inadvertent hypothermia in pediatric anesthesia. J Clin Monit Comput. 2019;33(6):1105-1112. Crossref
  • Kurz A, Sessler DI, Schroeder M, Kurz M. Thermoregulatory response thresholds during spinal anesthesia. Anesth Analg. 1993;77(4):721-726. Crossref
  • Leslie K, Sessler DI. Reduction in the shivering threshold is proportional to spinal block height. Anesthesiology. 1996;84(6):1327-1331. Crossref
  • Kim JS, Ikeda T, Sessler DI, Turakhia M, Jeffrey R. Epidural anesthesia reduces the gain and maximum intensity of shivering. Anesthesiology. 1998;88(4):851-857. Crossref
  • Joris J, Ozaki M, Sessler DI, Hardy AF, Lamy M, McGuire J, et al. Epidural anesthesia impairs both central and peripheral thermoregulatory control during general anesthesia. Anesthesiology. 1994;80(2):268-277. Crossref
  • Sessler DI. Perioperative thermoregulation and heat balance. Lancet. 2016;387(10038):2655-2664. Crossref
  • Cho SA, Chang M, Lee SJ, Sung TY, Cho CK. Prewarming for prevention of hypothermia in older patients undergoing hand surgery under brachial plexus block. Ann Geriatr Med Res. 2022;26(2):175-182. Crossref
  • Hynson J, Sessler DI. Intraoperative warming therapies: a comparison of three devices. J Clin Anesth. 1992;4(3):194-199. Crossref
  • Bickler P, Sessler DI. Efficiency of airway heat and moisture exchangers in anesthetized humans. Anesth Analg. 1990;71(4):415-418. Crossref
  • Giesbrecht GG, Ducharme MB, McGuire JP. Comparison of forced-air patient warming systems for perioperative use. Anesthesiology. 1994;80(3):671-679. Crossref
  • Ozaki M, Kurz A, Sessler DI, Lenhardt R, Schroeder M, Moayeri A, et al. Thermoregulatory thresholds during spinal and epidural anesthesia. Anesthesiology. 1994;81(2):282-288. Crossref
  • Brück K, Zeisberger E. Adaptive changes in thermoregulation and their neuropharmacological basis. Pharmacol Ther. 1987;35(1-2):163-215. Crossref
  • Recio-Pérez J, Miró Murillo M, Martin Mesa M, García JS, Santonocito C, Sanfilippo F, et al. Effect of prewarming on perioperative hypothermia in patients undergoing loco-Regional or general anesthesia: a randomized clinical trial. Medicina (Kaunas). 2023;59(12):2082. Crossref
  • Sessler DI. Perioperative Temperature Monitoring. Anesthesiology. 2021;134(1):111-118. Crossref
  • Bock M, Hohlfeld U, Von Engeln K, Meier PA, Motsch J, Tasman AJ. The accuracy of a new infrared ear thermometer in patients undergoing cardiac surgery. Can J Anaesth. 2005;52(10):1083-1087. Crossref
  • Boisson M, Alaux A, Kerforne T, Mimoz O, Debaene B, Dahyot-Fizelier C, et al. Intra-operative cutaneous temperature monitoring with zero-heat-flux technique (3M SpotOn) in comparison with oesophageal and arterial temperature: a prospective observational study. Eur J Anaesthesiol. 2018;35(11):825-830. Crossref
  • Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. Crossref
  • Horosz B, Malec-Milewska M. Methods to prevent intraoperative hypothermia. Anaesthesiol Intensive Ther. 2014;46(2):96-100. Crossref
  • Perlman R, Callum J, Laflamme C, Tien H, Nascimento B, Beckett A, et al. A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients. Crit Care. 2016;20(1):107. Crossref
  • Cobb B, Cho Y, Hilton G, Ting V, Carvalho B. Active warming utilizing combined IV fluid and forced-air warming decreases hypothermia and improves maternal comfort during cesarean delivery: a randomized control trial. Anesth Analg. 2016;122(5):1490-1497. Crossref
  • Min S, Yoon S, Yoon S, Bahk J, Seo J. Randomised trial comparing forced-air warming to the upper or lower body to prevent hypothermia during thoracoscopic surgery in the lateral decubitus position. Br J Anaesth. 2018;120(3):555-562. Crossref
  • Thiel B, Mooijer B, Kolff-Gart A, Kerklaan B, Poolman R, de Haan P, et al. Is preoperative forced-air warming effective in the prevention of hypothermia in orthopedic surgical patients? A randomized controlled trial. J Clin Anesth. 2020;61:109633. Crossref
  • Van Duren A. Perioperative prewarming: heat transfer and physiology. AORN J. 2022;115(5):407-422. Crossref
  • Madrid E, Urrútia G, Figuls MR, Pardo-Hernandez H, Campos JM, Paniagua P, et al. Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. Cochrane Database Syst Rev. 2016;4(4):CD009016. Crossref
  • Horn EP, Bein B, Böhm R, Steinfath M, Sahili N, Höcker J. The effect of short time periods of pre-operative warming in the prevention of peri-operative hypothermia. Anaesthesia. 2012;67(6):612-617. Crossref
  • Sultan P, Habib A, Cho Y, Carvalho B. The Effect of patient warming during Caesarean delivery on maternal and neonatal outcomes: a meta-analysis. Br J Anaesth. 2015;115(4):500-510. Crossref
  • Alparslan V, Kus A, Hosten T, Ertargin M, Ozdamar D, Toker K, Solak M. Comparison of forced-air warming systems in prevention of intraoperative hypothermia. J Clin Monit Comput. 2018;32(2):343-349. Crossref
  • Wang X, Su W, Yuqing M, Ge H, Chang W, Ma G, et al. Effectiveness of Forced-air Warming in Preventing Hypothermia During Laparoscopic Surgery: A RCT Meta-analysis. J Perianesth Nurs. 2025:S1089-9472(25)00172-8. Crossref
  • Lee Y, Kim K. Optimal application of forced air warming to prevent peri-operative hypothermia during abdominal surgery: a systematic review and meta-analysis. Int J Environ Res Public Health. 2021;18(5):2517. Crossref
  • Chen YC, Cherng YG, Romadlon DS, Chang KM, Huang CJ, Tsai PS, et al. Comparative effects of warming systems applied to different parts of the body on hypothermia in adults undergoing abdominal surgery: A systematic review and network meta-analysis of randomized controlled trials. J Clin Anesth. 2023;89:111190. Crossref
  • Fossum S, Hays J, Henson MM. A comparison study on the effects of prewarming patients in the outpatient surgery setting. J Perianesth Nurs. 2001;16(3):187-194. Crossref
  • Ji N, Wang J, Li X, Shang Y. Strategies for perioperative hypothermia management: advances in warming techniques and clinical implications: a narrative review. BMC Surg. 2024;24(1):425. Crossref
  • Roxby D, Sobieraj-Teague M, von Wielligh J, Sinha R, Kuss B, Smith AL, et al. Warming blood prior to transfusion using latent heat. Emerg Med Australas. 2020;32(4):604-610. Crossref
  • Munday J, Hines S, Wallace K, Chang AM, Gibbons K, Yates P. A systematic review of the effectiveness of warming interventions for women undergoing cesarean section. Worldviews Evid Based Nurs. 2014;11(6):383-393. Crossref
  • Campbell G, Alderson P, Smith AF, Warttig S. Warming of intravenous and irrigation fluids for preventing inadvertent perioperative hypothermia. Cochrane Database Syst Rev. 2015;2015(4):CD009891. Crossref
  • De Mattia AL, Barbosa MH, de Freitas Filho JP, Rocha Ade M, Pereira NH. Warmed intravenous infusion for controlling intraoperative hypothermia. Rev Lat Am Enfermagem. 2013;21(3):803-810. Crossref
  • Tubog TD, Kane TD, Ericksen AM. Combined Forced Air Warming and Warm Intravenous Fluid Strategy for Perioperative Hypothermia in Cesarean Delivery: A Systematic Review and Meta-Analysis. J Perianesth Nurs. 2023;38(1):21-32. Crossref
  • Balayssac D, Pereira B, Bazin JE, Le Roy B, Pezet D, Gagniere J. Warmed and humidified carbon dioxide for abdominal laparoscopic surgery: metaanalysis of the current literature. Surg Endosc. 2017;31(1):1-12. Crossref
  • Birch DW, Dang JT, Switzer NJ, Manouchehri N, Shi X, Hadi G, et al. Heated insufflation with or without humidification for laparoscopic abdominal surgery. Cochrane Database Syst Rev. 2016;10(10):CD007821. Crossref
  • Noll E, Diemunsch S, Pottecher J, Rameaux JP, Diana M, Sauleau E, et al. Prevention of laparoscopic surgery induced hypothermia with warmed humidified insufflation: is the experimental combination of a warming blanket synergistic? PLoS One. 2018;13(7):e0199369. Crossref
  • Wittenborn J, Mathei D, van Waesberghe J, Zeppernick F, Zeppernick M, Tchaikovski S, et al. The effect of warm and humidified gas insufflation in gynecological laparoscopy on maintenance of body temperature: a prospective randomized controlled multi-arm trial. Arch Gynecol Obstet. 2022;306(3):753-767. Crossref
  • Miyazaki R, Hoka S, Yamaura K. Visceral fat, but not subcutaneous fat, is associated with lower core temperature during laparoscopic surgery. PLoS One. 2019;14(6):e0218281. Crossref
  • Chen Y, Wang Y, Zhang YL, Zhang JJ, Hua Z, Li ZJ, et al. A prediction model for estimating risk of intraoperative hypothermia in patients undergoing general anesthesia: a prospective multicenter study. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2022;44(6):1028-1032. Crossref
Toplam 74 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Anesteziyoloji
Bölüm Derleme
Yazarlar

Feride Karacaer 0000-0002-1048-6505

Gönderilme Tarihi 8 Ocak 2026
Kabul Tarihi 17 Şubat 2026
Yayımlanma Tarihi 17 Mart 2026
IZ https://izlik.org/JA78PK73WS
Yayımlandığı Sayı Yıl 2026 Cilt: 9 Sayı: 1

Kaynak Göster

APA Karacaer, F. (2026). Perioperative Hypothermia: Mechanism, Risk Factors and New Protocols in Prevention and Treatment. Journal of Cukurova Anesthesia and Surgical Sciences, 9(1), 185-191. https://izlik.org/JA78PK73WS
https://dergipark.org.tr/tr/download/journal-file/11303