Rekonstrüktif Cerrahide Sığır Kaynaklı Aselüler Dermal Matriks (MatriDerm®) Kullanımı

Öz

Amaç: Bu makalede MatriDerm®’in farklı etiyojilere sahip çeşitli anatomik bölgelerdeki defektlerin onarımında başarılı bir şekilde kullanılabildiğinin ortaya koyulması amaçlanmıştır.

Gereç ve Yöntemler:  Pubmed’de anahtar kelimeler tarandı ve son on yılda MatriDerm® ve kısmı kalınlıkta deri grefti kullanılarak tek seanste onarılan defektlerin bildirildiği raporlar çalışmaya dahil edildi. Etiyolojik faktör ve anatomik bölge bilgisi olmayan vakalar ve yazı dili İngilizce olmayan makaleler çalışmaya dahil edilmedi. 24 ayrı çalışmadaki toplam 299 vakanın verileri değerlendirildi.

Bulgular: Matridermin büyük oranda travma (n:68, % 22,7), yanık (n:63, % 21), diyabetik ayak (n:62, % 20,7) ve flep donör alanlarında (n:50, % 16,7) kullanılmaktadır. Çoğunlukla alt ekstremite (n:58, % 52,8) ve üst ekstremite (n:118, % 39,5)deki defektlerin onarımında kullanılmaktadır.

Sonuç: Matriderm ve kısmi kalınlıkta deri grefti akut yanık, travma ve konjenital anomalilerde;  kontraktür açılmasına, tümör eksizyonuna, nekrotizan fasit gibi enfeksiyonlara sekonder yaralarda;  kronik ülserler ve diyabetik ayak yaralarında;  vücudun her bölgesindeki tam kat deri defekleri için güvenle kullanılabilir.

Anahtar Kelimeler

• dermal matriks,matriderm,deri grefti,rekonstrüksiyon,flep

Bovine Derived Acellular Dermal Matrix (MatriDerm®) Applications in Reconstructive Surgery

Abstract

Aim:  Pointing out that MatriDerm® can be applied to defects with wide range of etiologic factors at various anatomical regions is aimed.

Material and Methods: Keywords were searched at Pubmed and articles that report defects which were repaired at a single stage using MatriDerm® and split thickness skin graft are included. Cases that do not have etiologic factor and anatomical region information and articles whose main texts language are not English are excluded. Total of 299 cases from 24 reports are considered.

Findings: It is seen that MatriDerm® is applied mostly for trauma (n:68, 22.7 %), burn (n:63, 21 %), diabetic foot (n:62, 20.7 %) and flap donor area (n:50,  16 %).  It is used mainly for defects at  lower extremity (n:58, 52.8 %) and upper extremity (n:118,  39.5 %).

Conclusion : MatriDerm® with split thickness skin graft can be applied to trauma, burn, , diabetic foot  wounds, chronic ulsers, defects secondary to  necrotising fasciitis and scar contracture  release, tumor excision and congenital anomaly surgeries for reparing full thickness skin defects at any region of the body

Keywords

• dermal matrix,matriderm,skin graft,reconstruction,flap

Kaynakça

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