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Efficacy and safety of percutaneous nephrolithotomy in elderly patients: Experience of 128 cases

Yıl 2022, Cilt: 5 Sayı: 2, 222 - 228, 31.08.2022
https://doi.org/10.36516/jocass.1160492

Öz

OBJECTIVE: This study aimed to evaluate the efficacy and safety of percutaneous nephrolithotomy in elderly patients (≥65 years) with kidney stones > 2 cm in size.
PATIENTS AND METHODS: Patients aged ≥65 years who underwent percutaneous nephrolithotomy for kidney stones between January 2015 and January 2022 were included in this study. Patient profiles, preoperative stone data, operative information, and postoperative complications were reviewed. We applied the Guys Stone score to predict the net results of percutaneous nephrolithotomy.
RESULTS: Percutaneous nephrolithotomy was performed on 128 geriatric patients. Of these patients, 68 (53.1%) were male and 60 (46.9%) were female. The mean age was 69.87 ± 7.06 (65–80) years. The mean stone size was 28.7 ± 6.5 mm (22–46 mm). The mean operative time was 90.33 ± 40.56 min and fluoroscopy time was 5.16 ± 2.81 min. The reentry catheter was removed after an average of 3.21 ± 1.82 days. The mean duration of hospital stay was 3.17 ± 2.19 days. The stone-free survival rate was 90.6%. Transfusion was performed in four (3.1%) patients due to hemorrhage, and urine extravasation from the re-entry tract occurred in eight (6.2%) patients, and this required Double j-stent placement. When the four Guys stone score groups were compared, there was a statistically significant difference in stone-free rates (p = 0.001).
CONCLUSIONS: According to our results, percutaneous nephrolithotomy is a safe and effective treatment option for nephrolithiasis in the elderly, with high stone-free and acceptable complication rates.

Kaynakça

  • McCarthy JP, Skinner TA, Norman RW. Urolithiasis in the elderly. Can J Urol 2011; 18(3): 5717–5720.
  • Ordon M, Urbach D, Mamdani M, Saskin R, Honey RJ DA, Pace KT. A population based study of the changing demographics of patients undergoing definitive treatment for kidney stone disease. J Urol 2015; 193(3): 869–874.
  • Ghani KR, Sammon JD, Karakiewicz PI, Sun M, Bhojani N, Sukumar S, Trinh Q D. Trends in surgery for upper urinary tract calculi in the USA using the nationwide inpatient sample: 1999–2009. BJU Int 2013; 112(2): 224–230.
  • Sahin A, Atsu N, Erdem E, Öner S, Bilen C, Bakkaloğlu M, Kendi S. Percutaneous nephrolithotomy in patients aged 60 years or older. J Endourol 2001; 15(5): 489–491.
  • Stoller MS, Bolton DB, Lezin M, Lawrence M. Percutaneous nephrolithotomy in the elderly. Urology 1994; 44: 651–654.
  • Shohab D, Iqbal N, Alam MU, Butt A, Jamil MI, Hussain I, Akhter S. Comparison of Outcome of Percutaneous Nephrolithotomy in Adult Versus Paediatric Patients. J Coll Physicians Surg Pak 2016; 26(5): 371–373.
  • Sighinolfi MC, Micali S, Grande M, Mofferdin A, Stefani SD, Bianchi G. Extracorporeal shock wave lithotripsy in an elderly population: How to prevent complications and make the treatment safe and effective. J Endourol 2008; 22(10): 2223–2226.
  • Thomas K, Smith NC, Hegarty N, Glass JM. The Guy’s stone score--grading the complexity of percutaneous nephrolithotomy procedures. Urology 2011; 78(2): 277–281.
  • Tonner PH, Kampen J, Scholz J. Pathophysiological changes in the elderly. Best Pract Res Clin Anaesthesiol 2003; 17: 163–177.
  • Sieber FE. Postoperative delirium in the elderly surgical patient. Anesthesiol Clin 2009; 27: 451–464.
  • Anagnostou T, Thompson T, Ng CF, Moussa S, Smith G, Tolley DA. Safety and outcome of percutaneous nephrolithotomy in the elderly: retrospective comparison to a younger patient group. J Endourol 2008; 22: 2139–2146.
  • Nakamon T, Kitirattrakarn P, Lojanapiwat B. Outcomes of percutaneous nephrolithotomy: comparison of elderly and younger patients. Int Braz J Urol 2013; 39: 692–701.
  • Romero V, Akpinar H, Assimos DG. Kidney stones: A global picture of prevalence, incidence, and associated risk factors. Rev Urol 2010; 12(2-3): e86–96.
  • Resorlu B, Diri A, Atmaca A et al. Can we avoid percutaneous nephrolithotomy in high-risk elderly patients using the charlson comorbidity index? Urology 2012; 79 (5): 1042–1047.
  • Seitz C, Desai M, Häcker A, Hakenberg OW, Liatsikos E, Nagele U, Tolley D. Incidence, prevention, and management of complications following percutaneous nephrolitholapaxy. Eur Urol 2012; 61(1): 146–158.
  • Okeke Z, Smith AD, Labate G, D'Addessi A, Venkatesh R, Assimos D, de la Rosette, on behalf of the CROES PCNL Study Group, JJ. Prospective comparison of outcomes of percutaneous nephrolithotomy in elderly patients versus younger patients. J Endourol 2012; 26(8): 996–1001.
  • Ozturk H. Tubeless versus standard PCNL in geriatric population. Actas Urol Esp. 2015; 39(8): 494–501.

Yaşlı hastalarda perkütan nefrolitotominin etkinliği ve güvenilirliği: 128 vaka deneyimi

Yıl 2022, Cilt: 5 Sayı: 2, 222 - 228, 31.08.2022
https://doi.org/10.36516/jocass.1160492

Öz

AMAÇ: Bu çalışmada böbrek taşı > 2 cm olan yaşlı hastalarda (≥65 yaş) perkütan nefrolitotominin etkinlik ve güvenilirliğinin değerlendirilmesi amaçlanmıştır. HASTALAR VE YÖNTEM: Ocak 2015 ile Ocak 2022 tarihleri ​​arasında böbrek taşı nedeniyle perkütan nefrolitotomi uygulanan 65 yaş ve üzeri hastalar bu çalışmaya dahil edildi. Hasta profilleri, ameliyat öncesi taş verileri, ameliyat bilgileri ve ameliyat sonrası komplikasyonlar gözden geçirildi. Perkütan nefrolitotominin net sonuçlarını tahmin etmek için Guys Stone skorunu uyguladık. BULGULAR: 128 geriatrik hastaya perkütan nefrolitotomi uygulandı. Bu hastaların 68'i (%53,1) erkek, 60'ı (%46,9) kadındı. Ortalama yaş 69.87 ± 7.06 (65-80) yıldı. Ortalama taş boyutu 28.7 ± 6.5 mm (22-46 mm) idi. Ortalama ameliyat süresi 90.33 ± 40.56 dk ve floroskopi süresi 5.16 ± 2.81 dk idi. Yeniden giriş kateteri ortalama 3.21 ± 1.82 gün sonra çıkarıldı. Ortalama hastanede kalış süresi 3.17 ± 2.19 gündü. Taşsız sağkalım oranı %90.6 idi. Dört hastada (%3.1) kanama nedeniyle transfüzyon yapıldı ve sekiz hastada (%6.2) yeniden giriş yolundan idrar ekstravazasyonu meydana geldi ve bu, Double j-stent yerleştirilmesini gerektirdi. Dört Guys taş skor grubu karşılaştırıldığında, taşsızlık oranlarında istatistiksel olarak anlamlı bir fark vardı (p = 0.001). SONUÇ: Sonuçlarımıza göre, perkütan nefrolitotomi, yaşlılarda nefrolitiazis için yüksek taşsızlık ve kabul edilebilir komplikasyon oranları ile güvenli ve etkili bir tedavi seçeneğidir.

Kaynakça

  • McCarthy JP, Skinner TA, Norman RW. Urolithiasis in the elderly. Can J Urol 2011; 18(3): 5717–5720.
  • Ordon M, Urbach D, Mamdani M, Saskin R, Honey RJ DA, Pace KT. A population based study of the changing demographics of patients undergoing definitive treatment for kidney stone disease. J Urol 2015; 193(3): 869–874.
  • Ghani KR, Sammon JD, Karakiewicz PI, Sun M, Bhojani N, Sukumar S, Trinh Q D. Trends in surgery for upper urinary tract calculi in the USA using the nationwide inpatient sample: 1999–2009. BJU Int 2013; 112(2): 224–230.
  • Sahin A, Atsu N, Erdem E, Öner S, Bilen C, Bakkaloğlu M, Kendi S. Percutaneous nephrolithotomy in patients aged 60 years or older. J Endourol 2001; 15(5): 489–491.
  • Stoller MS, Bolton DB, Lezin M, Lawrence M. Percutaneous nephrolithotomy in the elderly. Urology 1994; 44: 651–654.
  • Shohab D, Iqbal N, Alam MU, Butt A, Jamil MI, Hussain I, Akhter S. Comparison of Outcome of Percutaneous Nephrolithotomy in Adult Versus Paediatric Patients. J Coll Physicians Surg Pak 2016; 26(5): 371–373.
  • Sighinolfi MC, Micali S, Grande M, Mofferdin A, Stefani SD, Bianchi G. Extracorporeal shock wave lithotripsy in an elderly population: How to prevent complications and make the treatment safe and effective. J Endourol 2008; 22(10): 2223–2226.
  • Thomas K, Smith NC, Hegarty N, Glass JM. The Guy’s stone score--grading the complexity of percutaneous nephrolithotomy procedures. Urology 2011; 78(2): 277–281.
  • Tonner PH, Kampen J, Scholz J. Pathophysiological changes in the elderly. Best Pract Res Clin Anaesthesiol 2003; 17: 163–177.
  • Sieber FE. Postoperative delirium in the elderly surgical patient. Anesthesiol Clin 2009; 27: 451–464.
  • Anagnostou T, Thompson T, Ng CF, Moussa S, Smith G, Tolley DA. Safety and outcome of percutaneous nephrolithotomy in the elderly: retrospective comparison to a younger patient group. J Endourol 2008; 22: 2139–2146.
  • Nakamon T, Kitirattrakarn P, Lojanapiwat B. Outcomes of percutaneous nephrolithotomy: comparison of elderly and younger patients. Int Braz J Urol 2013; 39: 692–701.
  • Romero V, Akpinar H, Assimos DG. Kidney stones: A global picture of prevalence, incidence, and associated risk factors. Rev Urol 2010; 12(2-3): e86–96.
  • Resorlu B, Diri A, Atmaca A et al. Can we avoid percutaneous nephrolithotomy in high-risk elderly patients using the charlson comorbidity index? Urology 2012; 79 (5): 1042–1047.
  • Seitz C, Desai M, Häcker A, Hakenberg OW, Liatsikos E, Nagele U, Tolley D. Incidence, prevention, and management of complications following percutaneous nephrolitholapaxy. Eur Urol 2012; 61(1): 146–158.
  • Okeke Z, Smith AD, Labate G, D'Addessi A, Venkatesh R, Assimos D, de la Rosette, on behalf of the CROES PCNL Study Group, JJ. Prospective comparison of outcomes of percutaneous nephrolithotomy in elderly patients versus younger patients. J Endourol 2012; 26(8): 996–1001.
  • Ozturk H. Tubeless versus standard PCNL in geriatric population. Actas Urol Esp. 2015; 39(8): 494–501.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Üroloji
Bölüm Makaleler
Yazarlar

Kadir Karkin 0000-0002-4324-3032

Ediz Vuruşkan 0000-0002-3446-0430

Erken Görünüm Tarihi 18 Ağustos 2022
Yayımlanma Tarihi 31 Ağustos 2022
Kabul Tarihi 13 Ağustos 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 5 Sayı: 2

Kaynak Göster

APA Karkin, K., & Vuruşkan, E. (2022). Efficacy and safety of percutaneous nephrolithotomy in elderly patients: Experience of 128 cases. Journal of Cukurova Anesthesia and Surgical Sciences, 5(2), 222-228. https://doi.org/10.36516/jocass.1160492

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