Combination Of Lymphocyte Count and Albumin Concentration As A New Prognostic Biomarker For Gastric Cancer

Yıl 2024, Cilt: 7 Sayı: 2, 73 - 77, 30.06.2024

Uğur Topal Orçun Yalav Burak Yavuz İsmail Cem Eray Abdullah Ülkü Gürhan Sakman Cem Kağan Parsak

Öz

Aim
This research links systemic inflammation and nutritional status with gastric cancer prognosis and postoperative outcomes.
Methods
Patients undergoing total gastrectomy for gastric adenocarcinoma (2015-2018) were categorized into two: Low Lymphocyte–Albumin(LA) score (Group 1) and High Lymphocyte-Albumin score (Group 2). Demographics, clinical data, operative outcomes, and survival rates were compared. The LA score's predictive ability for lymph node positivity was assessed.
Results
Using a cut-off value of 6069.7, Group 1 had 59 patients (low value) and Group 2 had 45 (high value). Hospital readmissions due to wound infections were higher in Group 1 (16.9% vs. 2.2%, p=0.041). Both groups had similar tumor localization and total lymph nodes removed, but Group 1 had more positive lymph nodes (4 vs. 2, p=0.026). Survival rates were comparable (32.59 vs. 31.32 months, p=0.390).
Conclusion
Low LA scores correlate with a higher number of positive lymph nodes, serving as a postoperative quality assessment indicator.

Anahtar Kelimeler

Gastric Cancer, Prognosis, Complication, Albumin, Lymphocyte Count

Kaynakça

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