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Tiroid kistlerine perkütan etanol enjeksiyonu

Yıl 2013, Cilt: 3 Sayı: 3, 142 - 145, 01.09.2013
https://doi.org/10.2399/jmu.2013003007

Öz

Amaç: Benign kistik tiroid nodülü olan ve Doppler ultrasonografi eşliğinde perkütan etanol enjeksiyonu (PEİ) uygulaması ile tedavi edilen 28 hastamızın sonuçları sunuldu. Yöntem: Perkütan etanol enjeksiyonu uygulamasından önce tüm hastalarda ince iğne aspirasyon biyopsisi ile malignite dışlandı. Kist hacmi uzunluk χ yükseklik χ en χ π/6 formülü kullanılarak hesaplandı. Uygulamada başlangıç kist hacminin yarısı kadar %95'lik etil alkol kullanıldı. Hastalarımızın takiplerinde nodül çapı, fibroskleroz oluşumu ve nodül vaskülarizasyonu değerlendirildi. Başlangıç hacmine göre %50'den fazla küçülme başarı olarak kabul edildi. Bulgular: Bir PEİ uygulaması ile hastalarımızın %88.5'inde tedavi edildi. Başarısız olgularda ikinci uygulamayla tedavi oranı %92.9'a yükseldi. Sonuç: Tiroid kistlerinin tedavisinde ultrason eşliğinde PEİ uygulaması yüksek başarı oranlarıyla etkili, ucuz ve güvenilir bir tedavi yöntemidir.

Kaynakça

  • Tanriover O, Comunoglu N, Eren B, et al. Occult papillary thy- roid carcinoma: prevalence at autopsy in Turkish people. Eur J Cancer Prev 2011;20:308-12.
  • De losSantos ET, Keyhani-Rofagha S, Cunningham JJ, Mazzaferri EL. Cystic thyroid nodules. The dilemma of malignant lesions. Arch Intern Med 1990;150:1422-7.
  • Roh JL, Park C 2nd. Treatment of benign thyroid cysts by intra- cystic injection of OK-432. Surgery 2008;144:775-9.
  • Garg MK, Satija L, Khanna SK, Saini JS. Intracystic tetracycline therapy for hypofunctioning cystic thyroid nodules. J Assoc Physicians India 2000;48:891-4.
  • Lee JH, Kim YS, Lee D, Choi H, Yoo H, Baek JH. Radiofrequ- encyablation (RFA) of benign thyroid nodules in patients within completely resolved clinical problems after ethanol ablation (EA). World J Surg 2010;34:1488-93.
  • Dİssing H, Bennedbaek FN, Hegedüs L. Beneficial effect of com- bined aspiration and interstitial laser therapy in patients with benign cystic thyroid nodules: a pilot study. Br J Radiol 2006;79 (948):943-7.
  • Cho YS, Lee HK, Ahn IM, et al. Sonographically guided ethanol sclerotherapy for benign thyroid cysts: result in 22 patients. AJR Am J Roentgenol 2000;174:213-6.
  • Clark OH, Okerlund MD, Cavalieri RR, Greenspan FS. Diagnosis and treatment of thyroid, parathyroid, and thyroglossal duct cysts. J Clin Endocrinol Metab 1979;48:983-8.
  • Jensen F, Rasmussen SN. The treatment of thyroid cysts by ultrasonically guided fine needle aspiration. Acta Chir Scand 1976; 142:209-11.
  • Edmonds CJ, Telle ZM. Thyroid cysts and their managements. Br Med J 1987;295:529-33.
  • Livraghi T, Paracchi A, Ferrari C, Reschini E, Nacchi RM, Bonifaino A. The treatment of autonomous thyroid nodules with percutaneous ethanol injection: 4 year experience. Radiology 1994; 190:529-33.
  • Vergès B, Buffier P, Baillot-Rudoni S, Brindisi MC, Bouillet B, Petit JM. Non-ultrasound-guided ethanol sclerotherapy for the treatment of thyroid cysts. Ann Endocrinol (Paris) 2011;72:203-7.
  • Monzani F, Lippi F, Goletti O, et al. Percutaneous aspiration and ethanol sclerotherapy for thyroid cysts. J Clin Endocrinol Metab 1994;78:800-2.
  • Bartos M, Pomorski L, Narebski J. The treatment of solitary thy- roid nodules in non-toxic goiter with 96% ethanol injections. [Article in Polish] Wiad Lek 1999;52:432-40.
  • Bennedbaek FN, Hegedüs L. Treatment of recurrent thyroid cysts with ethanol: a randomized double-blind controlled trial. J Clin Endocrinol Metab 2003;88:5773-7.
  • Sung JY, Baek JH, Kim YS, et al. One-step ethanol ablation of vis- cous cystic thyroid nodules. AJR Am J Roentgenol 2008;191:1730- 3.
  • Del Prete S, Caraglia M, Russo D, et al. Percutaneous ethanol injection efficacy in thetreatment of large symptomatic thyroid cys- tic nodules: ten-year follow-up of a large series. Thyroid 2002;12: 815-21.
  • Chu CH, Chuang MJ, Wang MC, Lam HC, Lu CC, Lee JK. Sclerotherapy of thyroid cystic nodules. J Formos Med Assoc 2003; 102:625-30.
  • Kim JH, Lee HK, Lee JH, Ahn IM, Choi CG. Efficacy of sono- graphically guided percutaneous ethanol injection for treatment of thyroid cysts versus solid thyroid nodules. AJR Am J Roentgenol 2003;180:1723-6.
  • This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY
  • NC-ND0) Licence (http://creativecommons.org/licenses/by-nc-nd/3.0/) which permits unrestricted noncommercial use, distribution, and reproduc
  • tion in any medium, provided the original work is properly cited.
  • Please cite this article as: Çetin B, Duman K, Karapınar U, Sa¤lam Ö, Dursun E. Percutaneous ethanol injection into thyroid cysts. J Med Updates 2013;3(3):142-145.

Percutaneous ethanol injection into thyroid cysts

Yıl 2013, Cilt: 3 Sayı: 3, 142 - 145, 01.09.2013
https://doi.org/10.2399/jmu.2013003007

Öz

Objective: To present the results of 28 patients who were treated by Doppler ultrasound guided percutaneous ethanol injection (PEI) into benign cystic thyroid nodules. Methods: Before percutaneous injection of ethanol, malignancies were excluded with fine needle aspiration biopsy. Volume of the nodule was calculated according to length χ width χ depth χ π/6 formula. During the application, 95% ethanol solution was injected about half of the initial cystic volume. At follow-up nodule diameter, formation of fibrosclerosis and nodule vascularization were evaluated. More than 50% reduction in nodule volume relative to the initial volume was defined success. Results: The success rate with single application of PEI was found 88.5 percent. With administration of the second application of PEI on unsuccessful cases success rate increased to 92.9 percent. Conclusion: Doppler ultrasound-guided PEI injection is a reliable, effective and inexpensive method in the treatment of thyroid cysts with high success rates.

Kaynakça

  • Tanriover O, Comunoglu N, Eren B, et al. Occult papillary thy- roid carcinoma: prevalence at autopsy in Turkish people. Eur J Cancer Prev 2011;20:308-12.
  • De losSantos ET, Keyhani-Rofagha S, Cunningham JJ, Mazzaferri EL. Cystic thyroid nodules. The dilemma of malignant lesions. Arch Intern Med 1990;150:1422-7.
  • Roh JL, Park C 2nd. Treatment of benign thyroid cysts by intra- cystic injection of OK-432. Surgery 2008;144:775-9.
  • Garg MK, Satija L, Khanna SK, Saini JS. Intracystic tetracycline therapy for hypofunctioning cystic thyroid nodules. J Assoc Physicians India 2000;48:891-4.
  • Lee JH, Kim YS, Lee D, Choi H, Yoo H, Baek JH. Radiofrequ- encyablation (RFA) of benign thyroid nodules in patients within completely resolved clinical problems after ethanol ablation (EA). World J Surg 2010;34:1488-93.
  • Dİssing H, Bennedbaek FN, Hegedüs L. Beneficial effect of com- bined aspiration and interstitial laser therapy in patients with benign cystic thyroid nodules: a pilot study. Br J Radiol 2006;79 (948):943-7.
  • Cho YS, Lee HK, Ahn IM, et al. Sonographically guided ethanol sclerotherapy for benign thyroid cysts: result in 22 patients. AJR Am J Roentgenol 2000;174:213-6.
  • Clark OH, Okerlund MD, Cavalieri RR, Greenspan FS. Diagnosis and treatment of thyroid, parathyroid, and thyroglossal duct cysts. J Clin Endocrinol Metab 1979;48:983-8.
  • Jensen F, Rasmussen SN. The treatment of thyroid cysts by ultrasonically guided fine needle aspiration. Acta Chir Scand 1976; 142:209-11.
  • Edmonds CJ, Telle ZM. Thyroid cysts and their managements. Br Med J 1987;295:529-33.
  • Livraghi T, Paracchi A, Ferrari C, Reschini E, Nacchi RM, Bonifaino A. The treatment of autonomous thyroid nodules with percutaneous ethanol injection: 4 year experience. Radiology 1994; 190:529-33.
  • Vergès B, Buffier P, Baillot-Rudoni S, Brindisi MC, Bouillet B, Petit JM. Non-ultrasound-guided ethanol sclerotherapy for the treatment of thyroid cysts. Ann Endocrinol (Paris) 2011;72:203-7.
  • Monzani F, Lippi F, Goletti O, et al. Percutaneous aspiration and ethanol sclerotherapy for thyroid cysts. J Clin Endocrinol Metab 1994;78:800-2.
  • Bartos M, Pomorski L, Narebski J. The treatment of solitary thy- roid nodules in non-toxic goiter with 96% ethanol injections. [Article in Polish] Wiad Lek 1999;52:432-40.
  • Bennedbaek FN, Hegedüs L. Treatment of recurrent thyroid cysts with ethanol: a randomized double-blind controlled trial. J Clin Endocrinol Metab 2003;88:5773-7.
  • Sung JY, Baek JH, Kim YS, et al. One-step ethanol ablation of vis- cous cystic thyroid nodules. AJR Am J Roentgenol 2008;191:1730- 3.
  • Del Prete S, Caraglia M, Russo D, et al. Percutaneous ethanol injection efficacy in thetreatment of large symptomatic thyroid cys- tic nodules: ten-year follow-up of a large series. Thyroid 2002;12: 815-21.
  • Chu CH, Chuang MJ, Wang MC, Lam HC, Lu CC, Lee JK. Sclerotherapy of thyroid cystic nodules. J Formos Med Assoc 2003; 102:625-30.
  • Kim JH, Lee HK, Lee JH, Ahn IM, Choi CG. Efficacy of sono- graphically guided percutaneous ethanol injection for treatment of thyroid cysts versus solid thyroid nodules. AJR Am J Roentgenol 2003;180:1723-6.
  • This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY
  • NC-ND0) Licence (http://creativecommons.org/licenses/by-nc-nd/3.0/) which permits unrestricted noncommercial use, distribution, and reproduc
  • tion in any medium, provided the original work is properly cited.
  • Please cite this article as: Çetin B, Duman K, Karapınar U, Sa¤lam Ö, Dursun E. Percutaneous ethanol injection into thyroid cysts. J Med Updates 2013;3(3):142-145.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Bilal Çetin Bu kişi benim

Kazım Duman Bu kişi benim

Uğur Karapınar Bu kişi benim

Ömer Sağlam Bu kişi benim

Engin Dursun Bu kişi benim

Yayımlanma Tarihi 1 Eylül 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 3 Sayı: 3

Kaynak Göster

APA Çetin, B., Duman, K., Karapınar, U., Sağlam, Ö., vd. (2013). Tiroid kistlerine perkütan etanol enjeksiyonu. Journal of Medical Updates, 3(3), 142-145. https://doi.org/10.2399/jmu.2013003007
AMA Çetin B, Duman K, Karapınar U, Sağlam Ö, Dursun E. Tiroid kistlerine perkütan etanol enjeksiyonu. Journal of Medical Updates. Eylül 2013;3(3):142-145. doi:10.2399/jmu.2013003007
Chicago Çetin, Bilal, Kazım Duman, Uğur Karapınar, Ömer Sağlam, ve Engin Dursun. “Tiroid Kistlerine perkütan Etanol Enjeksiyonu”. Journal of Medical Updates 3, sy. 3 (Eylül 2013): 142-45. https://doi.org/10.2399/jmu.2013003007.
EndNote Çetin B, Duman K, Karapınar U, Sağlam Ö, Dursun E (01 Eylül 2013) Tiroid kistlerine perkütan etanol enjeksiyonu. Journal of Medical Updates 3 3 142–145.
IEEE B. Çetin, K. Duman, U. Karapınar, Ö. Sağlam, ve E. Dursun, “Tiroid kistlerine perkütan etanol enjeksiyonu”, Journal of Medical Updates, c. 3, sy. 3, ss. 142–145, 2013, doi: 10.2399/jmu.2013003007.
ISNAD Çetin, Bilal vd. “Tiroid Kistlerine perkütan Etanol Enjeksiyonu”. Journal of Medical Updates 3/3 (Eylül 2013), 142-145. https://doi.org/10.2399/jmu.2013003007.
JAMA Çetin B, Duman K, Karapınar U, Sağlam Ö, Dursun E. Tiroid kistlerine perkütan etanol enjeksiyonu. Journal of Medical Updates. 2013;3:142–145.
MLA Çetin, Bilal vd. “Tiroid Kistlerine perkütan Etanol Enjeksiyonu”. Journal of Medical Updates, c. 3, sy. 3, 2013, ss. 142-5, doi:10.2399/jmu.2013003007.
Vancouver Çetin B, Duman K, Karapınar U, Sağlam Ö, Dursun E. Tiroid kistlerine perkütan etanol enjeksiyonu. Journal of Medical Updates. 2013;3(3):142-5.