Two Cases Of Complete Radiologic Response to Single Agent Chemotherapy of Elderly Inoperable Ovarian Cancer.

Öz

Ovarian cancer is the second most common gynecologic tumor in elderly women in Turkey and over 90% of ovarian

cancers had epithelial histology. Surgery and adjuvant chemotherapy is the standard approach but in elderly and unfit

patients there was no standard chemotherapy option. Here, we presented two cases reports treated with single agent

and had been showed complete radiologic and biochemical response without surgery.

Anahtar Kelimeler

• Elderly,ovarian cancer

Kaynakça

1. http://kanser.gov.tr/daire-faaliyetleri/kanser-istatistikleri.html.
2. Kyrgiou M, Salanti G, Pavlidis N, et al. Survival benefits with diverse chemotherapy regimens for ovarian cancer: meta-analysis of multiple treatments. J Natl Cancer Inst 2006; 98:1655.
3. Pignata S, Gabriella F, Giovanna S, et al. Poor Outcome of Elderly Patients with Platinum-sensitive Recurrent Ovarian Cancer: Results from the SOCRATES Retrospective Study. Crit Rev Oncol Hematol 2009;71: 233-241.
4. Maas HA, Kruitwagen RF, Lemmens VE, Goey SH, Janssen-Heijnen ML. The influence of age and co-morbidity on treatment and prognosis of ovarian cancer: a population-based study. Gynecol Oncol 2005; 97: 104-109.
5. Hershman D, Jacobson JS, McBride R, et al. Effectiveness of platinumbased chemotherapy among elderly patients with advanced ovarian cancer. Gynecol Oncol 2004; 94: 540-549.
6. Muralikrishnan S, Hatzis C, Katz A, Santin A, Schwartz PE, Abu-Khalaf MM. Chemotherapy for Elderly Ovarian Cancer Patients. Gynecol Obstet (Sunnyvale). 2016 ;6: 397-401.
7. Trédan O, Geay JF, Touzet S, et al. Carboplatin/cyclophosphamide or carboplatin/paclitaxel in elderly patients with advanced ovarian cancer? Analysis of two consecutive trials from the Groupe d'Investigateurs. Nationaux pour l'Etude des Cancers Ovariens. Ann Oncol 2007; 18: 256- 262.