Changes in MPVand PDW Values in Patients Receiving Chemotherapy for Colon and Gastric Cancers

Abstract

Kemoterapi alan kanser hastalarında tromboz eğiliminin arttığı günümüzde oldukça iyi bilinmektedir. Biz bu çalışmamızda bu hastalarda MPV ve PDW'daki değişiklikleri araştırdık. 169 gastrik ve 176 kolorektal kanser tanılı, 6 farklı kemoterapi protokolü uygulanan toplam 345 hasta çalışmamıza alındı. Medyan yaş 59 (23-80) olup 155’i  erkekti. Kemoterapi öncesi, ortası ve sonrasında trombosit sayısı, MPV ve PDW değerleri ölçüldü. Kemoterapi alan hastalarda trombosit sayısı ve MPV değerleri belirgin olarak azalırken PDW değerlerinin arttığı saptandı. Ayrıca, MPV, PDW değerleri ve vasküler tromboz, genel veya progresyonsuz sağkalım değişiklikleri arasında istatistiksel olarak anlamlı bir ilişki olmadığı görüldü.

Keywords

• Mide Ve Kolorektal Kanserler,Ortalama Trombosit Hacmi,Trombosit Dağılım Aralığı

Kaynakça

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