Vitiligo Hastalarında Sigara Kullanımının Hastalık Semptom ve Bulguları Üzerinde Etkisi Var Mıdır?

Öz

Amaç: Kliniğimizde vitiligo nedeniyle takip edilen hastalarda sigara kullanımının hastalık semptom ve bulguları üzerine etkisi olup olmadığını araştırmayı amaçladık.

Materyal ve Metod: Çalışmamızda Sakarya Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi (SÜEAH) Dermatoloji Kliniğinde poliklinik takibi olan hastaların retrospektif olarak dosyaları taranarak klinik ve laboratuvar verileri kayıt altına alındı. Hastaların demografik verileri, komorbid hastalıkları ve hastalıkları ile ilişkili bulguları retrospektif dosya verilerinden kaydedildi.

Bulgular: Çalışmaya 217 hasta alındı.  52 hasta sigara kullanan (grup I) ve 165 hasta sigara kullanmayan grupta (Grup II) idi. Grup I ile Grup II karşılaştırıldığında sigara kullananların yaş olarak daha büyük ve erkek baskınlığında olduğu görüldü. Sigara içmeyen grupta Keobner fenomeni, halo nevüs ve lökotrişi anlamlı derecede fazla saptandı. Repigmentasyon sigara içenlerde daha az izlendi. HDL düzeyi sigara içen grupta daha düşük bulundu.

Tartışma: Vitiligo hastalarında sigaranın bırakılması repigmentasyonun sağlanması açısından önemlidir.

Anahtar Kelimeler

• vitiligo,repigmentasyon,sigara

Does Smoking Have Impact on Symptoms and Signs of Disease in Vitiligo Patients?

Öz

Aim: We aimed to investigate whether smoking affects the symptoms and signs of vitiligo in patients followed up for vitiligo in our clinic.

Materials and Methods: In our study, the files of patients who were followed up in outpatient clinic in Dermatology Clinic of Sakarya University Medical Faculty Training and Research Hospital (SÜEAH) were retrospectively scanned and clinical and laboratory data were recorded. Patients' demographic data, comorbid diseases and their findings related to their diseases were recorded from retrospective file data.

Results: Two hundred and seventeen patients were included in the study. Fifty-two patients were in smokers group (group I) and 165 patients were in non-smokers group (Group II). When Group I and Group II were compared, it was seen that smokers were older and male dominated. Keobner phenomena, halo nevus and leukotrichia were significantly higher in nonsmoker group. Repigmentation was less frequent in smokers. HDL levels were lower in the smoker group.

Conclusion: Smoking cessation in vitiligo patients is important in terms of repigmentation.

Anahtar Kelimeler

• vitiligo,repigmentation,smoking

Kaynakça

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