Paclitaxel-Carboplatin based therapy in elderly patients with Non-small Cell Lung Cancer

Yıl 2017, Cilt: 3 Sayı: 2, 101 - 104, 22.06.2017

Özlem Özkul , Hasan Morcalı Bayram Kızılkaya Gökhan Puşuroğlu Yasemin Bakkal Temi Cemil Bilir

Öz

Background:
Nonsmall cell lung cancer (NSCLC) is increasingly seen in the elderly
population. At the time of diagnosis, more than half of the patients are over
65 years of age.

Method: We
retrospectively analyzed our hospital records. NSCLC patients treated with
combination either chemotherapy or combination with radiation according to the
stage.

Results: The median follow up period was 20 months and 9 (32%)
patients died during this period. Patients with stage IV patients had 7.9
months median OS, patients who had locally advanced stage had 19 months median
OS. Serum uric acid levels were significantly correlated with overall survival
and overall response rates in locally advanced disease (HR 1.01-2.4, P=0.05 and
0.02, respectively).

Conclusion: Our
results showed that combination therapy with taxanes and platinums can be
effective choice for selected elderly patients and we can use serum uric acid
levels as a prognostic factor who had advanced NSCLC.

Anahtar Kelimeler

elderly patients, uric acid

Kaynakça

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