A Term Fetus With Alobar Holoprosencephaly and Cyclopia: Case Report

Yıl 2017, Cilt: 3 Sayı: 3, 164 - 167, 28.09.2017

Hilal Uslu Yuvaci , İlker Ali Cerci Selçuk Özden

Öz

Alobar holoprosencephaly(HPE) is a rare, severe,
complex human brain malformation. We describe a case of cyclopia with alobar HPE identified at 40 weeks of gestation by 2-dimensional (2D)
and 3D transabdominal ultrasound (US).

A 27-year-old woman, gravida5, para4, abortion0, was
referred to our department at 40 weeks of gestation; she was experiencing labor
pains and had a nonreactive non-stress test. The mother had received no regular
antenatal care, and no sonography was performed during pregnancy. Both 2D and
3D US revealed alobar HPE and cyclopia. The baby was born by vaginal delivery
shortly thereafter and then died after birth. On examination, the face had a
single, large median eye and no nose. 

Alobar HPE and cyclopia can be diagnosed by US early
during pregnancy. Early diagnosis is important to allow for early termination
of pregnancy and to minimize the physiological and psychological impact of such
anomalies on the mother and family.

Anahtar Kelimeler

Alobar Holoprosencephaly, Cyclopia, Diagnosis, Ultrasonography

Kaynakça

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