Araştırma Makalesi

Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography

Cilt: 4 Sayı: 3 31 Aralık 2025
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Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography

Öz

Objective: This study aims to examine the differences in cerebrospinal fluid among patients with acute infarcts, chronic infarcts, and healthy controls by evaluating the density of cerebrospinal fluid via computed tomography (CT) scans of the brain. Materials and Methods: In this study, density measurements of cerebrospinal fluid (CSF) were retrospectively conducted from the lateral ventricle in a sample of 128 patients. The analysis incorporated diffusion-weighted magnetic resonance imaging (DWI) alongside CT scans of the brain. A circular region of interest (ROI) with an area of 0.25 cm² was consistently applied for the density measurements in each case. Results: The analysis of mean intraventricular density values in relation to infarct status revealed that individuals with acute infarction exhibited a mean density of 5.79 HU, which was the lowest recorded, while those without infarction had a mean density of 6.36 HU, representing the highest value. Conclusions: The analysis of changes in CSF using CT in acute and chronic stroke conditions plays a vital role in understanding the extent of neurological injury and in the development of appropriate therapeutic interventions. Evaluation of changes in CSF in acute and chronic infarctions plays a critical role in understanding the course of the disease.

Anahtar Kelimeler

Etik Beyan

Approval for ethical considerations was secured from the Ethics Committee and indicated by 06.02.2022 Decision No: 2022/25.

Kaynakça

  1. 1. Salaudeen MA, Bello N, Danraka RN, Ammani ML. Understanding the Pathophysiology of Ischemic Stroke: The Basis of Current Therapies and Opportunity for New Ones. Biomolecules. 2024;14(3):305.
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  3. 3. Huff T, Tadi P, Weisbrod LJ, Varacallo M. Neuroanatomy, Cerebrospinal Fluid. 2023 Aug 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–.
  4. 4. Alsbrook DL, Di Napoli M, Bhatia K, et al. Neuroinflammation in Acute Ischemic and Hemorrhagic Stroke. Curr Neurol Neurosci Rep. 2023 Aug;23(8):407-431.
  5. 5. Kakkar P, Kakkar T, Patankar T, et al. Current approaches and advances in the imaging of stroke. Dis Model Mech. 2021 Dec 1;14(12): dmm048785. Doi: 10.1242/dmm.048785. Epub 2021 Dec 7.
  6. 6. Tadi P, Lui F. Acute Stroke. 2023 Aug 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–.
  7. 7. Nehring SM, Tadi P, Tenny S. Cerebral Edema. 2023 Jul 3. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–.
  8. 8. Tomsick TA, Brott TG, Chambers AA, et al. Hyperdense middle cerebral artery sign on CT: efficacy in detecting middle cerebral artery thrombosis. AJNR Am J Neuroradiol. 1990 May;11(3):473-7.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Radyoloji ve Organ Görüntüleme

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

31 Aralık 2025

Gönderilme Tarihi

7 Kasım 2025

Kabul Tarihi

11 Aralık 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 4 Sayı: 3

Kaynak Göster

APA
Ünlü, S., Petik, B., Akçiçek, M., & Ilgar, M. (2025). Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography. Journal of Medical Topics and Updates, 4(3), 79-83. https://doi.org/10.58651/jomtu.1818474
AMA
1.Ünlü S, Petik B, Akçiçek M, Ilgar M. Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography. Journal of MTU. 2025;4(3):79-83. doi:10.58651/jomtu.1818474
Chicago
Ünlü, Serkan, Bulent Petik, Mehmet Akçiçek, ve Mehtap Ilgar. 2025. “Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography”. Journal of Medical Topics and Updates 4 (3): 79-83. https://doi.org/10.58651/jomtu.1818474.
EndNote
Ünlü S, Petik B, Akçiçek M, Ilgar M (01 Aralık 2025) Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography. Journal of Medical Topics and Updates 4 3 79–83.
IEEE
[1]S. Ünlü, B. Petik, M. Akçiçek, ve M. Ilgar, “Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography”, Journal of MTU, c. 4, sy 3, ss. 79–83, Ara. 2025, doi: 10.58651/jomtu.1818474.
ISNAD
Ünlü, Serkan - Petik, Bulent - Akçiçek, Mehmet - Ilgar, Mehtap. “Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography”. Journal of Medical Topics and Updates 4/3 (01 Aralık 2025): 79-83. https://doi.org/10.58651/jomtu.1818474.
JAMA
1.Ünlü S, Petik B, Akçiçek M, Ilgar M. Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography. Journal of MTU. 2025;4:79–83.
MLA
Ünlü, Serkan, vd. “Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography”. Journal of Medical Topics and Updates, c. 4, sy 3, Aralık 2025, ss. 79-83, doi:10.58651/jomtu.1818474.
Vancouver
1.Serkan Ünlü, Bulent Petik, Mehmet Akçiçek, Mehtap Ilgar. Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography. Journal of MTU. 01 Aralık 2025;4(3):79-83. doi:10.58651/jomtu.1818474