Kardiyovasküler risk faktörü olan hastalarda ana karotid, internal karotid, brakiyal, femoral arterler ve abdominal aorta intima-media kalınlığının B-Mod ultrasonografi ile değerlendirilmesi

Öz

Amaç: Bu çalışmada, farklı anatomik bölgelerden ölçülen intima-media kalınlığı (IMT) ile ana karotid IMT arasındaki ilişkiyi değerlendirmeyi amaçladık.

Yöntemler: 256 hasta prospektif olarak incelendi. B-mod ultrasound ile ana karotid, internal karotid, brakiyal ve femoral arter ile abdominal aort IMT değerleri ölçüldü (CC-IMT, IC-IMT, B-IMT, F-IMT ve A-IMT). Hastalar normal ve artmış CC- IMT değerlerine göre iki gruba ayrıldı. 

Bulgular: 256 hastanın 55’inde (%21,5) artmış CC-IMT tespit edildi. Tüm IMT değerleri CC-IMT ile pozitif olarak korelasyon göstermekteydi. Femoral IMT bağımsız olarak artmış CC-IMT ile ilişkiliydi. Regresyon analizine göre F-IMT'deki her 0,1 mm'lik artış, artmış CC-IMT riskini % 70,2 artırmaktaydı. F-IMT cut-off değeri 1,1 mm olarak kabul edildiğinde artmış CC-IMT varlığını %96,4 duyarlılık ve %90 özgüllük ile tespit etmekteydi. ROC eğri analizinde, eğri altında kalan alan değeri 0,936 olarak ölçüldü.

Sonuç: Artmış CC-IMT’i en iyi belirleyen diğer IMT bölgesi F-IMT olduğu bulundu. Klinik pratikte F-IMT sınır değeri olarak >1,1 mm kullanılabilir. CC-IMT ölçümü tüm diğer vasküler IMT ölçümü ile yakın ve pozitif olarak ilişkilidir.

Anahtar Kelimeler

• İntima-media kalınlığı,Ana karotid arter,Femoral arter

B-Mode ultrasound assessment of intima-media thickness of common carotid, internal carotid, brachial, femoral arteries and abdominal aorta in patients with cardiovascular risk factor

Abstract

Aim: The aim of the present study was to assess the association between common carotid intima-media thickness (IMT) and vascular IMT values measured from different anatomic regions.

Methods: We prospectively included 256 patients. The IMT values of the common carotid and internal carotid, brachial and femoral artery and abdominal aorta were measured by B-mode ultrasound (CC-IMT, IC-IMT, B-IMT, F-IMT and A-IMT). Patients were divided into two groups as increased and normal CC-IMT. 

Results: Increased CC-IMT was detected in 55 of 256 patients (21.5%). All IMT variables showed a positive correlation with CC-IMT. Femoral IMT was independently associated with increased CC-IMT. In regression model, each 0.1 mm increase in F-IMT increased the risk of increased CC-IMT by 70.2%. When F-IMT value 1.1 mm was accepted as a cut-off value for the prediction of increased CC-IMT, sensitivity and specificity were 96.4% and 90%, respectively. In ROC curve analyses, the area under curve was calculated as 0.936. 

Conclusions: Another vascular IMT location presenting increased CC-IMT best is F-IMT. The limit value for increased F-IMT >1.1mm may be used in practice. The CC-IMT measurement is closely and positively associated with all other vascular IMT measurements.

Keywords

• Intima-media thickness
• Common carotid artery
• Femoral artery

Kaynakça

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