Synchronous association of gastrointestinal stromal tumors of the jejunum and sigmoidal adenocarcinoma: A case report
Abstract
The association of a gastrointestinal stromal tumor (GIST) with an epithelial tumor of the digestive tract is very rare and frequently discovered by chance during the surgical treatment of digestive carcinoma. These tumors developed from the mesenchyme are known to have a good prognosis given their low malignancy potential. The possibility of a genetic mutation or an oncogenic agent capable of inducing tumors of different histotypes seems less plausible but it is not to be discarded. We report the case of a 74-year-old patient, operated for a sigmoid adenocarcinoma, with incidental discovery of a small bowel tumor whose histology confirmed the diagnosis of a GIST.
Keywords
Kaynakça
- 1. M’sakni I, Rammeh S, Chelbi E, et al. Adénocarcinome et tumeur stromale digestifs : association fortuite ou mécanisme oncogène commun : propos de deux observations. Ann Chir. 2006;131:464–7.
- 2. Miettinen M, Lasota J. Gastrointestinal stromal tumors pathology and prognosis at different sites. Semin Diagn Pathol. 2006;23:70–83.
- 3. Maiorana A, Fante R, Maria Cesinaro A, Adriana Fano R. Synchronous occurrence of epithelial and stromal tumors in the stomach: a report of a 6 cases. Arch Pathol Lab Med. 2000;124:682–6.
- 4. Kaffes A, Hughes L, Hollinshead J, Katelaris P. Synchronous primary adenocarcinoma, mucosa-associated lymphoid tis- sue lymphoma and a stromal tumor in a Helicobacter pylori infected stomach. J Gastroenterol Hepatol. 2002;17:1033–6.
- 5. Agaimy A, Wunsch PH, Sobin LH, et al. Occurrence of other malignancies in patients with gastrointestinal stromal tumors. Semin Diagn Pathol. 2006;23:120–9.
- 6. Wronski M, Ziarkiewicz-Wroblewska B, et al. Synchronous occurrence of gastrointestinal stromal tumors and other primary gastrointestinal neoplasms. World J Gastroenterol. 2006;12:5360–62.
- 7. Pandurengan RK, Dumont AG, Araujo DM, et al. Survival of patients with multiple primary malignancies: a study of 783 patients with gastrointestinal stromal tumor. Ann Oncol. 2010;21:2107–11.
- 8. Melis M, Choi EA, Anders R, et al. Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor (GIST). Int J Colorectal Dis. 2007;22:109–14.
Ayrıntılar
Birincil Dil
İngilizce
Konular
İç Hastalıkları
Bölüm
Olgu Sunumu
Yazarlar
Anas Belhaj
0000-0002-1118-1594
Morocco
Karim Ibn Majdoub
Bu kişi benim
0000-0002-0421-7296
Morocco
İmane Taughrai
Bu kişi benim
0000-0003-0401-3012
Morocco
Khalid Mazaz
Bu kişi benim
0000-0001-7779-7802
Morocco
Yayımlanma Tarihi
25 Şubat 2019
Gönderilme Tarihi
21 Eylül 2018
Kabul Tarihi
15 Kasım 2018
Yayımlandığı Sayı
Yıl 2019 Cilt: 3 Sayı: 2