Percutaneous transhepatic biliary drainage related infectious complications after living donor liver transplantation

Abstract

Aim: Biliary complications were the most common cause of morbidity after living donor liver transplantation. Percutaneous transhepatic biliary drainage (PTBD) is performed in this patients. The purpose of our study was to determine the rate of PTBD related infection (cholangitis and sepsis) after living donor liver transplantation.

Methods: This is a retrospective cohort study. Fifty two patients PTBD procedures were performed after living donor liver transplantation. Two main groups were established; Post PTBD infection group and non-infection group. Demographic characteristics, infectious complications and mortality rates were compared.

Results: PTBD procedure related infection (cholangitis and sepsis) rate was 52% (28 patients) and early (thirty days) mortality rate was 17.9% (5 patients). 

Conclusion: PTBD related infectious complication and mortality rates are high. In these patients we need to be very careful after PTBD.

Keywords

• Living donor liver transplantation,Percutaneous transhepatic biliary drainage,Infectious complications

Canlı vericili karaciğer nakli sonrası perkütan biliyer drenaja bağlı enfeksiyöz komplikasyonlar

Öz

Amaç: Biliyer komplikasyonlar canlı vericili karaciğer nakli sonrası en sık görülen morbidite nedenidir. Bu hastalarda perkütan transhepatik biliyer drenaj (PTBD) yapılır. Çalışmamızın amacı canlı vericili karaciğer nakli sonrası PTBD’ye bağlı enfeksiyon (kolanjit ve sepsis) oranını belirlemekti.

Yöntemler: Bu retrospektif bir çalışmadır. Elli iki hastaya canlı vericili karaciğer nakli sonrası PTBD işlemi uygulandı. Hastalar iki gruba ayrıldı. PTBD sonrası enfeksiyon gelişen ve gelişmeyen grup. Bu iki grubun demografik özellikleri, enfeksiyöz komplikasyonları ve mortalite oranları karşılaştırıldı.

Bulgular: PTBD prosedürüne bağlı enfeksiyon (kolanjit ve sepsis) oranı % 52 (28 hasta) ve erken (otuz gün) mortalite oranı % 17.9 (5 hasta) idi.

Sonuç: PTBD ile ilişkili infeksiyöz komplikasyon ve mortalite oranları yüksektir. Bu hastalarda PTBD'den sonra çok dikkatli olmak gerekir.

Anahtar Kelimeler

• Canlı vericili karaciğer nakli,Perkütan transhepatik biliyer drenaj,Enfeksiyöz komplikasyonlar

Kaynakça

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