Araştırma Makalesi
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Tekrarlanan elektrokonvulsif tedavilerde propofol indüksiyon dozu ve nöbet süresi arasında ilişki var mıdır?

Yıl 2019, , 861 - 864, 03.12.2019

Çiğdem Yıldırım Güçlü , Ahmet Onat Bermede Başak Ceyda Meço Zekeriyya Alanoğlu Neslihan Alkış

https://doi.org/10.28982/josam.595773

Öz

Amaç: Elektrokonvülsif tedavi için yıllardır anestezik ajanlar kullanılmıştır, ancak ajanın seçiminde bir zorluk vardır. Anestezikler, tedavinin başarısını doğrudan etkileyen nöbet süresi üzerinde olumsuz rol oynayabilir. Bu noktada, bu çalışma tekrarlayan seanslarda anestezik doz ve nöbet süresi arasındaki ilişkiyi görmek için tasarlanmıştır.

Yöntemler: Bu prospektif-kohort çalışmada toplam 11 hasta, 73 EKT tedavisi değerlendirildi. Premedikasyondan sonra, hastanın kirpik refleksi kaybolana dek yavaş yavaş propofol uygulandı. Nöbet süresi, uygulanan propofol dozu kaydedildi. İşlemin bitimi ile tam derlenme (Aldrete skoru ile karar verildi) arasındaki süre de kaydedildi.

Bulgular: Ortalama nöbet süresi 25,5 (10,2) saniye idi. Nöbet süresi, seans sayısı ve propofol dozu arasında istatistiksel olarak anlamlı bir korelasyon vardı. Aldrete skoru 10'a ulaşma süresi ile seans sayısı ve propofol dozu arasında korelasyon saptanmadı.

Sonuç: Seans sayısı arttıkça EKT sırasında artmış bir propofol dozu gerekebilir, ancak bu artış iyileşme süresini etkilemediği görülmüştür.

Anahtar Kelimeler

Elektrokonvülsif tedavi Propofol Nöbet

Kaynakça

  • 1. Fink M, Taylor MA. Electroconvulsive therapy. JAMA. 2007;298(3):330–2.
  • 2. Steven RJ, Tovel RM, Johnson JC, Delgado E. Anesthesia for electroconvulsive therapy. Anesthesiology. 1954;15(6):623–36.
  • 3. Wagner KJ, Mollenberg O, Rentrop M, Werner C, Kochs EF. Guide to anesthetic selection for electroconvulsive therapy. CNS Drugs. 2005;19:745–75.
  • 4. Ding Z, White PF. Anesthesia for electroconvulsive therapy. Anesth Analg. 2002;94:1351–64.
  • 5. Petrides G, Fink M. The ‘‘half-age’’ stimulation strategy for ECT dosing. Convuls Ther. 1996;12:138–46.
  • 6. Abrams R. Electroconvulsive Therapy. New York, NY: Oxford University Press; 2002.
  • 7. An den Broek WW, Leentjens AFG, van Vliet IM, et al. Hand-boek Elektroconvulsietherapie. Assen, the Netherlands: Koninklijke Van Gorkum. 2005.
  • 8. Rasmussen KG. Propofol for ECT Anesthesia a Review of the Literature. J ECT. 2014;30:210–5.
  • 9. Van Waarde JA, van Oudheusden LJ, Verwey B, Giltay EJ, van der Mast RC. Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study. Eur Arch Psychiatry Clin Neurosci. 2013;263:167–75.
  • 10. Bundy BD, Hewer W, Andres FJ, Gass P, Sartorius A. Influence of anesthetic drugs and concurrent psychiatric medication on seizure adequacy during electroconvulsive therapy. J Clin Psychiatry. 2010 Jun;71(6):775–7.
  • 11. Janouschek H, Nickl-Jockschat T, Haeck M, Gillmann B, Grözinger M. Comparison of methohexital and etomidate as anesthetic agents for electroconvulsive therapy in affective and psychotic disorders. J Psychiatr Res. 2013;47:686–93.
  • 12. Yalcin S, Aydogan H, Selek S, Kucuk A, Yuce HH, Karababa F, et al. Ketofol for electroconvulsive therapy anesthesia, two stones for one bird. J Anesth. 2012;26:562–7.

Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?

Yıl 2019, , 861 - 864, 03.12.2019

Çiğdem Yıldırım Güçlü , Ahmet Onat Bermede Başak Ceyda Meço Zekeriyya Alanoğlu Neslihan Alkış

https://doi.org/10.28982/josam.595773

Öz

Aim: Anesthetic agents have been used during electroconvulsive therapy for years, but selecting the agent remains a challenge. Anesthetics may play a negative role on seizure duration, which directly affects the success of the treatment. This study is designed to see the relationship of repetitive sessions, anesthetic dose, and seizure duration. 

Methods: A total of 73 ECT treatments for 11 patients were evaluated for this prospective-cohort study. After premedication, propofol was administered slowly until the patient lost eyelash reflex. The duration of the seizure, propofol dose administered, and the time between the end of the procedure and full recovery (as decided by Aldrete score) were recorded. 

Results: The mean seizure time was 25.5 (10.2) seconds. There was a statistically significant correlation between seizure duration, the number of sessions and propofol dose, and no correlation between the time to reach an Aldrete score of 10 and both the number of sessions and propofol dosing. 

Conclusion: An increased propofol dosage may be needed during ECT as the number of session increases, but this increase does not affect recovery time.

Anahtar Kelimeler

Electroconvulsive therapy Propofol Seizure

Kaynakça

  • 1. Fink M, Taylor MA. Electroconvulsive therapy. JAMA. 2007;298(3):330–2.
  • 2. Steven RJ, Tovel RM, Johnson JC, Delgado E. Anesthesia for electroconvulsive therapy. Anesthesiology. 1954;15(6):623–36.
  • 3. Wagner KJ, Mollenberg O, Rentrop M, Werner C, Kochs EF. Guide to anesthetic selection for electroconvulsive therapy. CNS Drugs. 2005;19:745–75.
  • 4. Ding Z, White PF. Anesthesia for electroconvulsive therapy. Anesth Analg. 2002;94:1351–64.
  • 5. Petrides G, Fink M. The ‘‘half-age’’ stimulation strategy for ECT dosing. Convuls Ther. 1996;12:138–46.
  • 6. Abrams R. Electroconvulsive Therapy. New York, NY: Oxford University Press; 2002.
  • 7. An den Broek WW, Leentjens AFG, van Vliet IM, et al. Hand-boek Elektroconvulsietherapie. Assen, the Netherlands: Koninklijke Van Gorkum. 2005.
  • 8. Rasmussen KG. Propofol for ECT Anesthesia a Review of the Literature. J ECT. 2014;30:210–5.
  • 9. Van Waarde JA, van Oudheusden LJ, Verwey B, Giltay EJ, van der Mast RC. Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study. Eur Arch Psychiatry Clin Neurosci. 2013;263:167–75.
  • 10. Bundy BD, Hewer W, Andres FJ, Gass P, Sartorius A. Influence of anesthetic drugs and concurrent psychiatric medication on seizure adequacy during electroconvulsive therapy. J Clin Psychiatry. 2010 Jun;71(6):775–7.
  • 11. Janouschek H, Nickl-Jockschat T, Haeck M, Gillmann B, Grözinger M. Comparison of methohexital and etomidate as anesthetic agents for electroconvulsive therapy in affective and psychotic disorders. J Psychiatr Res. 2013;47:686–93.
  • 12. Yalcin S, Aydogan H, Selek S, Kucuk A, Yuce HH, Karababa F, et al. Ketofol for electroconvulsive therapy anesthesia, two stones for one bird. J Anesth. 2012;26:562–7.
Toplam 12 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Anesteziyoloji
Bölüm Araştırma makalesi
Yazarlar

Çiğdem Yıldırım Güçlü 0000-0002-8416-3418

Ahmet Onat Bermede Bu kişi benim 0000-0002-8598-6264

Başak Ceyda Meço Bu kişi benim 0000-0003-2951-9634

Zekeriyya Alanoğlu Bu kişi benim 0000-0003-4967-5829

Neslihan Alkış Bu kişi benim 0000-0003-0469-2318

Yayımlanma Tarihi 3 Aralık 2019
Yayımlandığı Sayı Yıl 2019

Kaynak Göster

APA Yıldırım Güçlü, Ç., Bermede, A. O., Meço, B. C., Alanoğlu, Z., vd. (2019). Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?. Journal of Surgery and Medicine, 3(12), 861-864. https://doi.org/10.28982/josam.595773
AMA Yıldırım Güçlü Ç, Bermede AO, Meço BC, Alanoğlu Z, Alkış N. Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?. J Surg Med. Aralık 2019;3(12):861-864. doi:10.28982/josam.595773
Chicago Yıldırım Güçlü, Çiğdem, Ahmet Onat Bermede, Başak Ceyda Meço, Zekeriyya Alanoğlu, ve Neslihan Alkış. “Is There Any Relationship Between Propofol Induction Dose and Duration of Seizure for Repetitive Electroconvulsive Therapies?”. Journal of Surgery and Medicine 3, sy. 12 (Aralık 2019): 861-64. https://doi.org/10.28982/josam.595773.
EndNote Yıldırım Güçlü Ç, Bermede AO, Meço BC, Alanoğlu Z, Alkış N (01 Aralık 2019) Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?. Journal of Surgery and Medicine 3 12 861–864.
IEEE Ç. Yıldırım Güçlü, A. O. Bermede, B. C. Meço, Z. Alanoğlu, ve N. Alkış, “Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?”, J Surg Med, c. 3, sy. 12, ss. 861–864, 2019, doi: 10.28982/josam.595773.
ISNAD Yıldırım Güçlü, Çiğdem vd. “Is There Any Relationship Between Propofol Induction Dose and Duration of Seizure for Repetitive Electroconvulsive Therapies?”. Journal of Surgery and Medicine 3/12 (Aralık 2019), 861-864. https://doi.org/10.28982/josam.595773.
JAMA Yıldırım Güçlü Ç, Bermede AO, Meço BC, Alanoğlu Z, Alkış N. Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?. J Surg Med. 2019;3:861–864.
MLA Yıldırım Güçlü, Çiğdem vd. “Is There Any Relationship Between Propofol Induction Dose and Duration of Seizure for Repetitive Electroconvulsive Therapies?”. Journal of Surgery and Medicine, c. 3, sy. 12, 2019, ss. 861-4, doi:10.28982/josam.595773.
Vancouver Yıldırım Güçlü Ç, Bermede AO, Meço BC, Alanoğlu Z, Alkış N. Is there any relationship between propofol induction dose and duration of seizure for repetitive electroconvulsive therapies?. J Surg Med. 2019;3(12):861-4.