Suriyeli mülteciler arasında Hepatit B, Hepatit C ve HIV seroprevalansı: Türkiye'deki bir üçüncü basamak merkezinden kesitsel bir çalışma

Öz

Amaç: Hepatit B (HBV), Hepatit C (HCV) ve İnsan İmmün Yetmezlik Virüsü (HIV) tüm dünyada ciddi sağlık sorunlarına neden olmaktadır. Suriye'deki son çatışmalar ve savaş nedeniyle, birçok göçmen kontrollü ve / veya kontrolsüz bir şekilde Türkiye'ye girmiştir. Bu çalışmada hastanemize başvuran Suriyeli göçmenlerde HBV, HCV ve HIV seroprevalansının belirlenmesi amaçlandı.

Yöntemler: Bu kesitsel çalışma 01.01.2015 - 14.05.2018 tarihleri arasında Ankara Yüksek İhtisas Eğitim ve Araştırma Hastanesi'nde yapıldı. Hastalardan alınan serum örnekleri ELISA (Enzim-Bağımlı İmmunosorbent Testi) yöntemiyle çalışılarak, HBV yüzey antijeni (HBsAg), anti-HBs, HCV antikoru (anti-HCV) ve anti-HIV titreleri araştırıldı.

Bulgular: Çalışmaya alınan 244 hastanın 154'u erkek (%63,11), 90'ı kadındı (%36,89). HBV seroprevalansı erkekler ve kadınlar arasında anlamlı farklılık göstermedi ve sırasıyla %5,84 ve %5,55 olarak bulundu (P>0,05). Anti-HCV pozitif bulunan hasta sayısı 6 (%2,46) 6 idi. HCV seroprevalansı erkeklerde %1,29, kadınlarda %4,44 olarak bulundu. Bu 244 hastanın hiçbirinde anti-HIV pozitifliği tespit edilmedi.

Sonuç: Çalışmamızda Suriyeli göçmenlerde HBV ve Anti-HIV seroprevalansının lokal verilere benzer olduğunu, ancak anti-HCV pozitifliğinin lokal verilere göre daha yüksek olduğu gözlenmiştir. Yaşa bağlı insidans oranları da farklı bulundu. Bu verilerin bilinmesinin, göçmenler için önleyici ve terapötik önlemlerin planlanması açısından önemli olduğuna inanıyoruz.

Anahtar Kelimeler

• Hepatit B,Hepatit C,İnsan immün yetmezlik virüsü,Suriyeli mülteciler

Hepatitis B, Hepatitis C and HIV seroprevalence among Syrian refugees: A cross-sectional study from a tertiary referral center in Turkey

Öz

Aim: Hepatitis B (HBV), Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV) cause serious health problems all over the world. Due to the recent conflicts and war in Syria, many immigrants have entered Turkey in a controlled and / or uncontrolled manner. In this study, we aimed to determine HBV, HCV, and HIV seroprevalence among Syrian migrants who were referred to our hospital.

Methods: This cross-sectional study was performed between 01/01/2015 - 14/05/2018 in Ankara Yuksek Ihtisas Training and Research Hospital. Serum samples from patients were evaluated for positivity of HBV surface antigen (HBsAg), antibodies against HBV surface antigen (anti-HBs), HCV antibody (anti-HCV) and anti-HIV with the Enzyme-Linked Immunosorbent Assay (ELISA) method.

Results: Among 244 patients included in the study, 154 were male (63.11%) and 90 were female (36.89%). Seroprevalences of HBV were 5.84% and 5.55%, respectively, the difference between which was statistically insignificant (P>0.05). Anti-HCV was positive in 6 (2.46%) patients. HCV seroprevalence rates were 1.29% in men, and 4.44% in women. None of these 244 patients had anti-HIV positivity.

Conclusion: In our study, we found that the seroprevalences of HBV and Anti-HIV in Syrian migrants were similar to domestic values, but that of anti-HCV was higher. Age-related incidence rates also differed. We believe that the knowledge of these data is important in terms of planning preventive and therapeutic measures for migrants.

Anahtar Kelimeler

• Hepatitis B,Hepatitis C,Human immunodeficiency virus,Syrian refugees

Kaynakça

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