The effect on conception rates of bladder fullness during intrauterine insemination: A retrospective cohort study

Yıl 2020, , 289 - 292, 01.04.2020

Zeyneb Bakacak

https://doi.org/10.28982/josam.703914

Öz

Aim: Embryo transfer in in-vitro fertilization (IVF) cycles is performed with a full bladder, being careful to avoid surgical instrumentation to the cervix as much as possible, so that uterine contractions are not stimulated. The aim of this study was to investigate whether a full bladder during the application of intrauterine insemination increased pregnancy rates by correcting the cervico-uterine axis, thereby enabling easier access of sperm to the uterine cavity.
Methods: This study included 61 patients undergoing IUI procedures, which were performed on patients with infertility since at least one year and those with at least one open oviduct as seen on hysterosalpingography (HSG). Patients’ demographic data, folliculometry measurements, spermiogram parameters, bladder fullness status on abdominal ultrasonography during the application, and beta hGC levels on the 14th day following the application were recorded from the patient files.
Results: No statistically significant differences were determined between the two groups in terms of demographic data and folliculometry measurements. The conception rate was 20% in the full bladder group, and 12% in the empty bladder group. Tenaculum application was at a statistically significantly higher rate in the empty bladder group than in the full bladder group (P<0.001). The conception rate was insignificantly higher in the full bladder group (P=0.342).
Conclusion: A full bladder facilitates sperm access to the uterine cavity and may increase conception rates. There is a need for further prospective randomized studies with a larger series to obtain better results.

Anahtar Kelimeler

Bladder fullness;, Conception rate, Intrauterine insemination

İntrauterin inseminasyon esnasında mesane doluluğunun gebelik oranlarına etkisi: Retrospektif kohort çalışma

Öz

Amaç: In vitro fertilizasyon (IVF) sikluslarında embriyo transferleri uterus kontraksiyonlarını uyarmamak için mümkün mertebe servikse cerrahi alet enstrümentasyonundan kaçınmaya dikkat edilerek ve dolu mesane ile yapılır. Çalışmamızda da intrauterin inseminasyon uygulaması esnasında da mesane doluluğunun serviko-uterin aksı düzeltip spermlerin uterin kaviteye erişimini kolaylaştırarak gebelik oranlarını artırıp artırmadığını araştırmayı amaçladık.
Yöntemler: Bu çalışmaya histerosalpingografisinde en az bir tüpünün açık olduğu tespit edilip en az bir yıllık infertilitesi olan ve intrauterin inseminasyon tedavisi yapılan 61 hasta dahil edilmiştir. Hastaların demografik özellikleri, folikülometri ölçümleri, spermiogram parametreleri, uygulama esnasındaki abdominal ultrasonografide mesane doluluk durumu ve uygulama sonrası 14. günde beta hGC kaydedildi.
Bulgular: İki grup arasında demografik özellikler, folikülometri ölçümleri açısından istatistiksel olarak anlamlı fark yoktu. Gebelik oranı mesane grubunda %20, boş mesane grubunda %12 olarak bulundu. Tenakulum uygulama oranı boş mesane grubunda dolu mesane grubundan anlamlı düzeyde yüksek bulundu (P<0,001). Gebelik oranı dolu mesane grubunda daha yüksek olmasına rağmen, fark anlamlı bir seviyeye ulaşmadı (P=0,342).
Sonuç: Dolu mesane, spermlerin uterin boşluğuna erişimini kolaylaştırıp gebe kalma oranını artırabilir. Daha iyi sonuçlar elde etmek için daha geniş serilerle yapılacak prospektif randomize çalışmaların gerekli olduğuna inanıyoruz.

Anahtar Kelimeler

İntrauterin inseminasyon, Mesane doluluğu, Gebelik oranı

Kaynakça

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