Is overactive bladder a risk factor for erectile dysfunction? A cross-sectional study

Abstract

Aim: Erectile dysfunction (ED) is a sexual dysfunction characterized by the inability to achieve or maintain penile erection during sexual activity. Many risk factors have been identified in ED-related epidemiological studies. In experimental studies, a relationship is thought to exist between Overactive Bladder (OAB) and ED. We investigated the relationship between OAB and ED, its clinical reflections, and the odds ratio of OAB for ED. Methods: We conducted this cross-sectional prospective study between January-July 2020. Sixty patients referred to the urology outpatient clinic with complaints of OAB (Group 1) and 66 patients without urological complaints (Group 2) were included in the study. Patients’ erectile functions were evaluated with the IIEF-5 form. OAB was evaluated with the OAB-V8 form. Results: The groups were similar in terms of age, body mass index, comorbidity, and smoking status. IIEF-5 scores were higher in Group 2 [20.52 (3.51)] compared to Group 1 [18.17 (5.46)] (P=0.036). Correlation analysis between IEF-5 and OAB-V8 scores revealed a negative correlation; it was observed that the IIEF-5 score decreased as the OAB-V8 score increased (r=-0.260, P=0.045). The odds ratio of decreasing IIEF-5 score with each 1-unit increase of OAB-V8 score was 0.164 (P=0.04). It was observed that the patients diagnosed with OAB had lower IIEF-5 scores when they had nocturia. Conclusion: OAB is a risk factor for ED. The presence of nocturia symptoms is remarkable for ED in OAB patients. The effect of OAB should not be ignored in the treatment of ED.

Keywords

• Erectile Dysfunction
• IIEF-5
• ; OAB
• Overactive Bladder

Aşırı aktif mesane erektil disfonksiyon için bir risk faktörü müdür? Kesitsel çalışma

Öz

Amaç: Erektil disfonksiyon (ED), cinsel aktivite sırasında penis ereksiyonunun sağlanamaması veya sürdürülememesi ile karakterize bir cinsel işlev bozukluğudur. ED ile ilişkili epidemiyolojik çalışmalarda birçok risk faktörü tanımlanmıştır. Deneysel çalışmalarda Aşırı Aktif Mesane (OAB) ile ED arasında bir ilişki olduğu düşünülmektedir. Bu çalışmamızda OAB ve ED arasındaki ilişkiyi, klinik yansımalarını ve ED için OAB'nin risk oranını araştırmayı amaçladık. Yöntemler: Bu kesitsel çalışmayı Ocak 2020 ve Temmuz 2020 arasında gerçekleştirdik. OAB (Grup 1) şikayetleri ile üroloji polikliniğine başvuran 60 hasta ve ürolojik şikayeti olmayan 66 hasta (Grup 2) çalışmaya dahil edildi. Hastaların erektil fonksiyonları IIEF-5 formu ile aşırı aktif mesane sorgulaması OAB-V8 formu ile değerlendirildi. Bulgular: Gruplar yaş, vücut kitle indeksi, komorbidite ve sigara içme durumu açısından benzerdi. IIEF-5 skorları Grup 2'de [20,52 (3,51)] Grup-1'e [18,17 (5,46)] göre daha yüksek bulundu (P=0,036). IEF-5 score ve OAB-V8 score arasında yapılan korelasyon analizinde negatif korelasyon saptandı; OAB-V8 skoru arttıkça IIEF-5 skorunun düştüğü gözlendi (r -0,260, P=0,045). OAB-V8 skorunun her 1 birim artışında IIEF-5 puanınında ki azalma risk oranı 0,164 olarak bulunmuştur (P=0.04). OAB tanısı alan hastalarda noktüri varlığında IIEF-5 skorlarının daha düşük olduğu gözlendi. Sonuç: OAB, ED için bir risk faktörüdür. Noktüri semptomlarının varlığı OAB hastalarında ED için dikkat çekicidir. ED tedavisinde OAB'nin etkisi göz ardı edilmemelidir.

Anahtar Kelimeler

• Erektil Disfonksiyon
• IIEF-5
• OAB
• Aşırı Aktif Mesane

Kaynakça

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