Tiroid ince iğne aspirasyon biyopsisi: Nodüllerin radyolojik özelliklerinin sitolojik yeterlilik oranına etkisi

Yıl 2020, , 790 - 793, 01.09.2020

Cennet Şahin , Bade Von Bodelschwingh

https://doi.org/10.28982/josam.792221

Öz

Amaç: Tiroid ince iğne aspirasyon biyopsisi (İİAB), tiroid nodüllerinin tanısında kullanılan ucuz ve mikroinvaziv bir işlemdir. Bununla birlikte, biyopsilerin % 40'ına kadarında sitoloji yetersiz gelebilir. Bu çalışma, tiroid nodüllerinin radyolojik özelliklerinin sitolojik yeterlilik oranına etkisini değerlendirmeyi amaçlamıştır.
Yöntemler: Kliniğimizde, 2016-2019 yılları arasında tiroid nodul İİAB'si yapılan hastalar bu retrospektif kohort çalışmada incelendi. Nodüllerin tanısal yeterlilik oranı ve radyolojik özellikleri (boyut, kistik komponent, kalsifikasyon içeriği, ekojenite, sınır özelliği) not edildi ve aralarındaki ilişki araştırıldı.
Bulgular: Toplam 525 hastada (%77 kadın, %23 erkek; ortalama yaş 53.3; yaş aralığı 14-87) 595 nodüle İİAB yapıldı. Nodüllerin ortalama çapı 20.1 mm (min: 4 mm; maks: 60 mm) idi. Biyopsilerin %25'inde tanısal yetersizlik saptandı. Makrokalsifikasyon içeren nodüllerde yeterlilik anlamlı olarak düşüktü (P=0.036). Nodüllerin yeterlilik oranları ile ekojenite, sınır özelliği, solid yapısı veya boyutu arasında anlamlı bir ilişki yoktu (her biri için P>0.05).
Sonuç: Bazı radyolojik özellikler, yetersiz örneklemenin habercisi olabilir. Bununla birlikte, radyolojik özelliklerin yanı sıra çeşitli dış faktörler de sitopatolojik yeterliliği etkiler. Bu nodüllerde ek teknikler gerekebilir.

Anahtar Kelimeler

Tiroid nodülü, Ultrason, Biyopsi, Radyoloji

Thyroid fine needle aspiration biopsy: The effect of radiological features of nodules on cytological adequacy

Öz

Aim: Thyroid fine needle aspiration biopsy (FNAB) is an inexpensive and microinvasive procedure used in the diagnosis of thyroid nodules. However, cytology may be insufficient in up to 40% of biopsies. This study aimed to assess the effect of radiological features of thyroid nodules on cytological adequacy.
Methods: The patients who underwent thyroid FNAB between 2016 and 2019 in our clinic were reviewed in this retrospective cohort study. Diagnostic adequacy rate and radiological features of nodules (size, cystic component, calcification content, echogenicity, margin feature) were noted and their relationship was investigated.
Results: A total of 525 patients (77% female, 23% male; mean age 53.3 years; age range 14-87) had FNAB for 595 nodules. Mean diameter of the nodules was 20.1 mm (min: 4mm; max: 60 mm). Of the all biopsies, 25% were inadequate for diagnosis. Adequacy was significantly low in nodules containing macrocalcification (P=0.036). There was no significant relationship between adequacy and echogenicity, margin feature, solid structure or size of the nodules (P>0.05 for each).
Conclusion: Some radiological features may be predictive of inadequate sampling. Nevertheless, varied extrinsic factors affect cytopathological adequacy besides radiological features. Additional techniques may be required in these nodules.

Anahtar Kelimeler

Tyroid nodule, ultrasound, biopsy, radiology

Kaynakça

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