Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules

Yıl 2020, Cilt: 7 Sayı: 1, 143 - 150, 15.02.2020

Özgür Yılmaz

https://doi.org/10.18596/jotcsa.627805

Cited By: 5

Öz

In this work, new trans-diamide derivatives were synthesized with the
reaction between fumaryl chloride and substituted anilines. After
successful synthesis of trans-amides, antioxidant activity of all
synthesized molecules was investigated via DPPH method and calculated
IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR,
19F-NMR, GC-MS and FTIR spectroscopic techniques.

Anahtar Kelimeler

Amides, DPPH method, Antioxidant activity

Destekleyen Kurum

Mersin University

Proje Numarası

BAP 2017-1-AP1-2188

Teşekkür

This research was supported by a grant from Mersin University (BAP 2017-1-AP1-2188). The author would like to thanks to Prof. Dr. Nermin SIMSEK KUS (Mersin University) for offering the laboratory facilities, and to Dr. Pinar KUCE CEVIK (Mersin University) for assistance with antioxidant measurement.

Kaynakça

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