Atypical bacteria and acute asthma: Is there a role for antibiotics?
Abstract
Atypical bacteria(Mycoplasma pneumoniae and Chlamydophila pneumoniae) are thought to be inflicted in the pathogenesis and precipitation of acute asthma. Past and current infections with these organisms were found more frequently in asthmatics compared to healthy controls. It was suggested that atypical infections could precipitate acute asthma attacks in previously healthy individuals. This has raised the question of whether or not to add antibiotics to the management, especially macrolides. This review highlights the natural history of these organisms and their role in acute asthma of children. The current literature about role of antibiotics in acute asthma is summarized.
Keywords
Kaynakça
- Specjalski K, Jassem E. Chlamydophila pneumoniae, Mycoplasma pneumoniae infections, and asthma control. Allergy Asthma Proc. 2011; 32(2):9-17.
- Teig N, Anders A, Schmidt C, Rieger C, Gatermann S. Chlamydophila pneumoniae and Mycoplasma pneumoniae in respiratory specimens of children with chronic lung diseases. Thorax. 2005; 60(11):962-6.
- Eaton MD, van Herick W, Meiklejohn G. Studies on the etiology of primary atypical pneumonia : iii. Specific neutralization of the virus by human serum. J Exp Med. 1945; 31; 82(5):329-42. Waites KB, Talkington DF. Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev. 2004; 17(4):697-728.
- Annagür A, Kendirli SG, Yilmaz M, Altintas DU, Inal A. Is there any relationship between asthma and asthma attack in children and atypical bacterial infections; Chlamydia pneumoniae, Mycoplasma pneumoniae and Helicobacter pylori. J Trop Pediatr. 2007; 53(5):313-8.
- Marrie TJ, Costain N, La Scola B, Patrick W, Forgie S, Xu Z, McNeil SA. The role of atypical pathogens in community-acquired pneumonia. Semin Respir Crit Care Med. 2012; 33(3):244-56. Tsolia MN, Psarras S, Bossios A, Audi H, Paldanius M, Gourgiotis D, Kallergi K, Kafetzis DA, Constantopoulos A, Papadopoulos NG. Etiology of community-acquired pneumonia in hospitalized school-age children: evidence for high prevalence of viral infections. Clin Infect Dis. 2004; 1; 39(5):681-6.
- Principi N, Esposito S, Blasi F, Allegra L; Mowgli study group. Role of Mycoplasma pneumoniae and Chlamydia pneumoniae in children with community-acquired lower respiratory tract infections. Clin Infect Dis. 2001; 32(9):1281-9.
- Samransamruajkit R, Jitchaiwat S, Wachirapaes W, Deerojanawong J, Sritippayawan S, Prapphal N. Prevalence of Mycoplasma and Chlamydia pneumonia in severe community-acquired pneumonia among hospitalized children in Thailand. Jpn J Infect Dis. 2008 Jan; 61(1):36-9.
- Chu HW, Honour JM, Rawlinson CA, Harbeck RJ, Martin RJ. Effects of respiratory Mycoplasma pneumoniae infection on allergen-induced bronchial hyperresponsiveness and lung inflammation in mice. Infect Immun. 2003; 71(3):1520-6.
Ayrıntılar
Birincil Dil
İngilizce
Konular
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Bölüm
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Yazarlar
Mohammed Abdel Fattah
Bu kişi benim
Yayımlanma Tarihi
14 Nisan 2014
Gönderilme Tarihi
30 Ocak 2014
Kabul Tarihi
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Yayımlandığı Sayı
Yıl 1970 Cilt: 6 Sayı: 0