To study the efficacy and safety of injectable ketamine in pediatric ward procedure in age group of 6 month to 12 year in tertiary care hospital

Abstract

Background: The literature concerning the efficacy and safety of ketamine for conscious sedation during procedures in pediatric ward was reviewed.

Aims: To see the efficacy and safety of injectable ketamine in pediatric ward procedure in age group of 6 month to 12 year in tertiary care hospital and parental satisfaction. Settings and Design: prospective unicentric, interventional, pilot study. Patients admitted in pediatric ward in tertiary care medical college hospital.

Methods and Material: Ketamine 1mg/kg intravenously given in fifteen-twenty second to patients goes into different ward procedure except in exclusion criteria. If adequate effect not produced within five minutes, same dose is repeated. Time required for dissociation, duration of effect, pre & post procedural heart rate, respiratory rate, blood pressure and oxygen saturation and other significant side effects were recorded after five & thirty  minutes. Vitals and behaviour monitoring was done for twenty four hours after procedure. Statistical analysis used: basic biostatistics used.

Results: During study period twenty three patients were studied. Three patients were excluded from data analysis in study as per exclusion criteria. Twenty patients were analyzed. Peak effect seen within one to five minute after injection.  Heart rate, respiratory rate, systolic and diastolic blood pressure rise in all patients and return to base line after thirty minute. Side effect including vomiting seen in one patient and increase salivation in five patients but no active management required. Repeat dose required in three patients.

Conclusions: we found that ketamine in dose of 1mg/kg  is alone effective and safe drug and is suitable for use in children requiring conscious sedation for variety of painful and anxiety producing procedures with good parental satisfaction. Side effects encountered were minimal and no intensive management required in any patient due to side effects.

Keywords

• conscious sedation
• ketamine
• and pediatric ward
• painful invasive procedur

Kaynakça

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