Yıl 2012, Cilt 4 , Sayı 3, Sayfalar 1 - 6 2012-08-17

Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology

Kumaraguru D [1] , Poovazhagi VARADARAJAN [2] , Shanthi SANGAREDDİ [3] , Ramachandran PADMANABHAN [4] , Jeyachandran P [5]


Objective: A randomized controlled trial was undertaken at the pediatric intensive care department of a tertiary care Pediatric hospital at Chennai, to evaluate the effectiveness of 3% saline as an anti-edema measure in comparison to mannitol in children with non-traumatic coma. Subjects: The study comprised of 40 children with cerebral edema in each group. Outcome measures: The outcome was analyzed in terms of survival/death, duration of coma and complications. Results: Study parameters like age, gender, Glasgow coma scale, etiology of coma, signs of cerebral edema and duration of coma were comparable among the two groups and did not reveal statistically significant difference. Among the complications shock(p- 0.03) and dehydration (p-0.045) were more common in children who received mannitol and hypernatremia(p-0.026) was common in children who received 3% saline. The mortality rates among the two groups did not reveal statistically significant difference(p-0.07). Conclusions: In the treatment of cerebral edema of non traumatic origin in children, 3% saline can be considered as effective and safe as mannitol.
Mannitol, 3% saline, cerebral edema
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Birincil Dil en
Bölüm Original Articles
Yazarlar

Yazar: Kumaraguru D

Yazar: Poovazhagi VARADARAJAN

Yazar: Shanthi SANGAREDDİ

Yazar: Ramachandran PADMANABHAN

Yazar: Jeyachandran P

Tarihler

Yayımlanma Tarihi : 17 Ağustos 2012

Bibtex @ { jps202226, journal = {Journal of Pediatric Sciences}, issn = {}, eissn = {1309-1247}, address = {}, publisher = {Bilal YILDIZ}, year = {2012}, volume = {4}, pages = {1 - 6}, doi = {10.17334/jps.30271}, title = {Effectiveness of 3\% saline versus mannitol in children with cerebral oedema of non traumatic etiology}, key = {cite}, author = {D, Kumaraguru and Varadarajan, Poovazhagi and Sangareddi̇, Shanthi and Padmanabhan, Ramachandran and P, Jeyachandran} }
APA D, K , Varadarajan, P , Sangareddi̇, S , Padmanabhan, R , P, J . (2012). Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology . Journal of Pediatric Sciences , 4 (3) , 1-6 . Retrieved from https://dergipark.org.tr/tr/pub/jps/issue/19087/202226
MLA D, K , Varadarajan, P , Sangareddi̇, S , Padmanabhan, R , P, J . "Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology" . Journal of Pediatric Sciences 4 (2012 ): 1-6 <https://dergipark.org.tr/tr/pub/jps/issue/19087/202226>
Chicago D, K , Varadarajan, P , Sangareddi̇, S , Padmanabhan, R , P, J . "Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology". Journal of Pediatric Sciences 4 (2012 ): 1-6
RIS TY - JOUR T1 - Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology AU - Kumaraguru D , Poovazhagi Varadarajan , Shanthi Sangareddi̇ , Ramachandran Padmanabhan , Jeyachandran P Y1 - 2012 PY - 2012 N1 - DO - T2 - Journal of Pediatric Sciences JF - Journal JO - JOR SP - 1 EP - 6 VL - 4 IS - 3 SN - -1309-1247 M3 - UR - Y2 - 2021 ER -
EndNote %0 Journal of Pediatric Sciences Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology %A Kumaraguru D , Poovazhagi Varadarajan , Shanthi Sangareddi̇ , Ramachandran Padmanabhan , Jeyachandran P %T Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology %D 2012 %J Journal of Pediatric Sciences %P -1309-1247 %V 4 %N 3 %R %U
ISNAD D, Kumaraguru , Varadarajan, Poovazhagi , Sangareddi̇, Shanthi , Padmanabhan, Ramachandran , P, Jeyachandran . "Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology". Journal of Pediatric Sciences 4 / 3 (Ağustos 2012): 1-6 .
AMA D K , Varadarajan P , Sangareddi̇ S , Padmanabhan R , P J . Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology. Journal of Pediatric Sciences. 2012; 4(3): 1-6.
Vancouver D K , Varadarajan P , Sangareddi̇ S , Padmanabhan R , P J . Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology. Journal of Pediatric Sciences. 2012; 4(3): 1-6.
IEEE K. D , P. Varadarajan , S. Sangareddi̇ , R. Padmanabhan ve J. P , "Effectiveness of 3% saline versus mannitol in children with cerebral oedema of non traumatic etiology", Journal of Pediatric Sciences, c. 4, sayı. 3, ss. 1-6, Ağu. 2012, doi:10.17334/jps.30271

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