Clinicopathological features of patients with coexistence of secondary hyperparathyroidism and incidental papillary thyroid carcinoma

Yıl 2024, Cilt: 17 Sayı: 1, 24 - 29, 08.01.2024

Gökalp Okut Murat Karataş Ali Murat Yıldırım Mehmet Alperen Uğur

Öz

Objective: The clinicopathological features of Secondary hyperparathyroidism (SHPT)-associated papillary thyroid carcinoma (PTC) are unclear and further investigation is required. In this study, it was aimed to evaluate the rate of PTC and tumor characteristics in the results of thyroidectomy performed for non-tumor reasons in patients with SHPT.
Material and Methods: The data of 54 patients who underwent thyroidectomy with parathyroidectomy due to SHPT were analyzed. The patients were divided into two groups; patients with thyroid malignancy (group M) and patients without (group B).
Results: PTC was detected in 12 (22.2%) of 54 patients who underwent parathyroidectomy and thyroidectomy for SHPT. There was no difference between the groups in terms of gender (p=0.95), age (p=0.75), duration of hemodialysis (p=0.30). Preoperative mean parathormone level was higher in patients with malignancy (p=0.02). The thyroid nodule sizes of the patients in Group M were statistically significantly larger (17.8 ± 9.1 mm vs 13.09 ± 4.73 mm, p=0.02). Recurrence of PTC developed in the 19th month of the follow-up in one of our patients. The mean follow-up period of all patients was 22 ± 20.72 months.
Conclusion: In order not to overlook the association of PTC in patients with SHPT, surgeons should perform adequate preoperative examinations and be more careful during surgery

Anahtar Kelimeler

secondary hyperparathyroidism, papillary thyroid carcinoma, end stage renal disease

Kaynakça

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