Araştırma Makalesi
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Yıl 2020, Cilt 4, Sayı 4, 223 - 236, 07.11.2020

Öz

Kaynakça

  • AZARI, S., and ZOU, L. 2012, Using zwitter ionic amino acid l-DOPA tomodify the surface of thin film composite polyamide reverse osmosis membranes to increase their fouling resistance. J. Memb. Sci., 401–402, 68–75.
  • BASTIDE, M.F., et al., 2015, Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson’sdisease. Prog. Neurobiol., 132, 96–168.
  • BENZA K.R., GASH B., KLEBOVICH I, 1996, Determination of Methyldopa in Human Plasma by Validated HPLC with fluorescence detection, Journal of Chromatography, 730, 125-131.
  • DE D, P., DI GIOVANNI, G., and Millan, M.J., 2017, Expanding the repertoire of L-DOPA’sactions: A comprehensive review of its functional neurochemistry. Prog. Neurobiol., 151, 57–100.
  • DI GIOVANNI, G., CHAGRAOUI, A., PUGINIER, E., GALATI, S., and DE DEURWAERDÈRE, P., 2019, Reciprocal interaction between monoaminergic systems and the pedunculopontine nucleus: Implication in the mechanism of L-DOPA. Neurobiol. Dis., 128, 9–18.
  • FOULADGAR, M., KARIMI, M.H., 2013, Ionic Liquid/Multiwall Carbon Nanotubes Paste Electrode for Square WaweVoltammetic Determination of Methyldopa, 19, 1163-70.
  • GHOLIVAND M.B., AMIRI, M., 2009, Preparation of Polypyrrole/Nuclear Fast Red Films on Gold Electrode and Its Application on the Electrocatalytic Determination of Methyldopa and Ascorbic Acid, Electroanalysis, 21,22, 2461-67.
  • HAUSER, R.A. 2009, Levodopa: Past, Present, and Future. Eur. Neurol., 62 (1), 1–8.
  • HUANG F., JIN G., LIU Y., KONG J., 2008, Sensitive Determination of Phenylephrine and Chlorprothixene at Poly (4-aminobenzene sulfonic acid)-Modified Glassy Carbon Electrode, Talanta, 1435-41.
  • JIN G., ZHANG Y., CHENG W., 2005, Poly (p-aminobenzene sulfonic acid)-Modified Glassy Carbon Electrode for Simultaneous of Dopamine and Ascorbic Acid, Sensors and Actuators B, 107, 52834.
  • MERCURI, N., and BERNARDI, G. (2005) The ‘magic’ of -dopa: why is it the gold standard Parkinson’s disease therapy? Trends Pharmacol. Sci., 26 (7), 341–344.
  • MO, J.W., OGOREVC, B., 2005, Simultaneous Measurement of Dopamine and Ascorbate at Their Physiological Levels Using Voltammetric Microprobe Based on Over oxidized Poly (1,2-Phenylenediamine)-Coated Carbon Fiber. Analytical Chemistry, 73, 1196-1202.
  • MU, K., ZHANG, D., SHAO, Z., QıN, D., WANG, Y., WANG, S. 2017 Enhanced permeability and anti fouling performance of cellulose acetate ultra filtration membrane assisted by l-DOPA functionalized halloysite nanotubes. Carbohydr. Polym., 174, 688–696.
  • MURRAY R.W., EWING A.G., DURST A.R., 1987, ChemicallyModifiedElectrodes Molecular Design for Electroanalysis, AnalyticalChemistry, 59 (5), 379A-390A
  • NOROUZI, P., GANJALI, M.R., SHAHTAHERİ S.J., DINARVAND, R., HAMZEHPOOR, 2009, A., Monitoring of Methyldopa by Fast Fourier Transform Continuous Cyclic Voltammetry at Gold Microelectrode, Chinese Journal of Chemistry, 27, 732-38.
  • ÖZDEMİR, N, 2006 Karbon ve Metal Elektrotların Bazı Aromatik Aminlerle Elektrokimyasal Modifikasyonu ve Karakterizasyonu, (Yüksek Lisans Tezi), Ankara Üniversitesi.
  • REDDAIAH, K., REDDY, T.M., RAGHU, P., 2012, Electrochemical investigation of L-dopa and simultaneous resolution in the presence of uric acid and ascorbic acid at a poly (methylorange) film coated electrode: A voltammetric study, Journal of Electroanalytical Chemistry, 682, 164-171.
  • REZAEI, B., ASKARPOUR, N., ENSAFI, A.A., 2013, Adsorptive Stripping Voltammetry Determination of Methyldopa on the Surface of a Carboxylated Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode in Biological and Pharmaceutical Samples, Colloids and Surfaces B: Biointerfaces, 109, 253-58.
  • SAĞLIKOĞLU, G., 2011, Nitroimidazol Türevi Antibakteriyel Etkili İlaç Aktif Maddelerinin Dozaj Formlarından Modifiye ve Modifiye Edilmemiş Elektrotlarda Voltametrik Teknikler ile Kantitatif Analizi, (Doktora Tezi), Çanakkale Onsekiz Mart Üniversitesi Fen Edebiyat Fakültesi.
  • SHAHROKHIAN S., RASTGAR S., 2011, Electrodeposition of Pt-Runanoparticles on Multi-walled Carbon Nanotubes: Application in Sensitive Voltammetric Determination of Methyldopa, Electrochimica Acta, 58, 125-33.
  • SKRZYPEK S., CIESIELSKI W., SOKOŁOWSKI A., YILMAZ S., KAZMIERCZAK D., 2005 ElectrochemicalStudy of Famotidine-Analytical Application toUrine, Talanta, 66, 1146-1151,
  • STRADIOTTO, N.R., YAMANAKA, H., AND ZANONI, M.V.B., 2003, Electrochemical sensors: a powerful tool in analytical chemistry. J. Braz. Chem. Soc., 14 (2), 159–173.
  • SUBAK, H., OZKAN, A.D, 2018, Label-free electrochemical biosensor for the detection of Influenza genes and the solution of guanine-based displaying problem of DNA hybridization, Sensors and Actuators B: Chemical, 263, 196-207.
  • YANG Z., HU G., LIU Y., ZHAO J., ZHAO G., 2006, Poly(p-aminobenzene sulfonic acid)-Modified Glassy Carbon Electrode for Selective Determination of Hydroquinone in the Presence of Catechol and Resorcinol, Canadian Journal of Analytical Sciences and Spectroscopy, 52, 1, 11-17.

DEVELOPMENT OF ELECTROCHEMICAL SENSORS FOR QUANTITATIVE ANALYSIS OF METHYLDOPA AT MODIFIED-GCE AND PGE ELECTRODES BY VOLTAMMETRY

Yıl 2020, Cilt 4, Sayı 4, 223 - 236, 07.11.2020

Öz

Methyldopa is one of the important drugs used in the treatment of high blood pressure (hypertension). In addition to various methods such as chromatographic and spectrophotometric methods, electrochemical methods are used for the determination of methyldopa. However, poly (p-aminobenzene sulfonic acid), pen-tip graphite electrode (PGE) study was not found in the literature search. Modified electrodes are important because they increase the sensitivity of the analysis. Furthermore, electrochemical methods have advantages such as being faster and cheaper than other instrumental analysis methods, being more sensitive, not requiring long pretreatments in the preparation of samples. In this study, the glassy carbon electrode (GCE) was modified with poly(p-aminobenzene sulfonic acid) to prepare poly (p-aminobenzene sulfonic acid) -modified glassy carbon electrodes. Cyclic voltammetry (CV) technique was used for the electropolymerization process. Methyldopa was selected in various concentrations of phosphate pH 7.40 buffer, anodic and cathodic voltamograms were taken and oxidation and reduction properties were investigated. Measurements were taken at different scanning rates by CV technique and the current type of methyldopa was determined. Peak flow-concentration graphs were drawn from the measurements taken by Differential Pulse Voltammetry (DPV) technique and the linearity range was 0.020- 2.500 µM for modified-GCE and 0.020-2.820 µM for PGE. The limit of detection (LOD) was calculated as 0.006 µM for modified-GCE, 0.012 µM for PGE. The limit of quantification (LOQ) was calculated as 0.020 µM for modified-GCE and 0.040 µM for PGE.

Kaynakça

  • AZARI, S., and ZOU, L. 2012, Using zwitter ionic amino acid l-DOPA tomodify the surface of thin film composite polyamide reverse osmosis membranes to increase their fouling resistance. J. Memb. Sci., 401–402, 68–75.
  • BASTIDE, M.F., et al., 2015, Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson’sdisease. Prog. Neurobiol., 132, 96–168.
  • BENZA K.R., GASH B., KLEBOVICH I, 1996, Determination of Methyldopa in Human Plasma by Validated HPLC with fluorescence detection, Journal of Chromatography, 730, 125-131.
  • DE D, P., DI GIOVANNI, G., and Millan, M.J., 2017, Expanding the repertoire of L-DOPA’sactions: A comprehensive review of its functional neurochemistry. Prog. Neurobiol., 151, 57–100.
  • DI GIOVANNI, G., CHAGRAOUI, A., PUGINIER, E., GALATI, S., and DE DEURWAERDÈRE, P., 2019, Reciprocal interaction between monoaminergic systems and the pedunculopontine nucleus: Implication in the mechanism of L-DOPA. Neurobiol. Dis., 128, 9–18.
  • FOULADGAR, M., KARIMI, M.H., 2013, Ionic Liquid/Multiwall Carbon Nanotubes Paste Electrode for Square WaweVoltammetic Determination of Methyldopa, 19, 1163-70.
  • GHOLIVAND M.B., AMIRI, M., 2009, Preparation of Polypyrrole/Nuclear Fast Red Films on Gold Electrode and Its Application on the Electrocatalytic Determination of Methyldopa and Ascorbic Acid, Electroanalysis, 21,22, 2461-67.
  • HAUSER, R.A. 2009, Levodopa: Past, Present, and Future. Eur. Neurol., 62 (1), 1–8.
  • HUANG F., JIN G., LIU Y., KONG J., 2008, Sensitive Determination of Phenylephrine and Chlorprothixene at Poly (4-aminobenzene sulfonic acid)-Modified Glassy Carbon Electrode, Talanta, 1435-41.
  • JIN G., ZHANG Y., CHENG W., 2005, Poly (p-aminobenzene sulfonic acid)-Modified Glassy Carbon Electrode for Simultaneous of Dopamine and Ascorbic Acid, Sensors and Actuators B, 107, 52834.
  • MERCURI, N., and BERNARDI, G. (2005) The ‘magic’ of -dopa: why is it the gold standard Parkinson’s disease therapy? Trends Pharmacol. Sci., 26 (7), 341–344.
  • MO, J.W., OGOREVC, B., 2005, Simultaneous Measurement of Dopamine and Ascorbate at Their Physiological Levels Using Voltammetric Microprobe Based on Over oxidized Poly (1,2-Phenylenediamine)-Coated Carbon Fiber. Analytical Chemistry, 73, 1196-1202.
  • MU, K., ZHANG, D., SHAO, Z., QıN, D., WANG, Y., WANG, S. 2017 Enhanced permeability and anti fouling performance of cellulose acetate ultra filtration membrane assisted by l-DOPA functionalized halloysite nanotubes. Carbohydr. Polym., 174, 688–696.
  • MURRAY R.W., EWING A.G., DURST A.R., 1987, ChemicallyModifiedElectrodes Molecular Design for Electroanalysis, AnalyticalChemistry, 59 (5), 379A-390A
  • NOROUZI, P., GANJALI, M.R., SHAHTAHERİ S.J., DINARVAND, R., HAMZEHPOOR, 2009, A., Monitoring of Methyldopa by Fast Fourier Transform Continuous Cyclic Voltammetry at Gold Microelectrode, Chinese Journal of Chemistry, 27, 732-38.
  • ÖZDEMİR, N, 2006 Karbon ve Metal Elektrotların Bazı Aromatik Aminlerle Elektrokimyasal Modifikasyonu ve Karakterizasyonu, (Yüksek Lisans Tezi), Ankara Üniversitesi.
  • REDDAIAH, K., REDDY, T.M., RAGHU, P., 2012, Electrochemical investigation of L-dopa and simultaneous resolution in the presence of uric acid and ascorbic acid at a poly (methylorange) film coated electrode: A voltammetric study, Journal of Electroanalytical Chemistry, 682, 164-171.
  • REZAEI, B., ASKARPOUR, N., ENSAFI, A.A., 2013, Adsorptive Stripping Voltammetry Determination of Methyldopa on the Surface of a Carboxylated Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode in Biological and Pharmaceutical Samples, Colloids and Surfaces B: Biointerfaces, 109, 253-58.
  • SAĞLIKOĞLU, G., 2011, Nitroimidazol Türevi Antibakteriyel Etkili İlaç Aktif Maddelerinin Dozaj Formlarından Modifiye ve Modifiye Edilmemiş Elektrotlarda Voltametrik Teknikler ile Kantitatif Analizi, (Doktora Tezi), Çanakkale Onsekiz Mart Üniversitesi Fen Edebiyat Fakültesi.
  • SHAHROKHIAN S., RASTGAR S., 2011, Electrodeposition of Pt-Runanoparticles on Multi-walled Carbon Nanotubes: Application in Sensitive Voltammetric Determination of Methyldopa, Electrochimica Acta, 58, 125-33.
  • SKRZYPEK S., CIESIELSKI W., SOKOŁOWSKI A., YILMAZ S., KAZMIERCZAK D., 2005 ElectrochemicalStudy of Famotidine-Analytical Application toUrine, Talanta, 66, 1146-1151,
  • STRADIOTTO, N.R., YAMANAKA, H., AND ZANONI, M.V.B., 2003, Electrochemical sensors: a powerful tool in analytical chemistry. J. Braz. Chem. Soc., 14 (2), 159–173.
  • SUBAK, H., OZKAN, A.D, 2018, Label-free electrochemical biosensor for the detection of Influenza genes and the solution of guanine-based displaying problem of DNA hybridization, Sensors and Actuators B: Chemical, 263, 196-207.
  • YANG Z., HU G., LIU Y., ZHAO J., ZHAO G., 2006, Poly(p-aminobenzene sulfonic acid)-Modified Glassy Carbon Electrode for Selective Determination of Hydroquinone in the Presence of Catechol and Resorcinol, Canadian Journal of Analytical Sciences and Spectroscopy, 52, 1, 11-17.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Basic Sciences and Engineering
Yazarlar

Suzan YANIK>
CANAKKALE ONSEKIZ MART UNIVERSITY
0000-0002-0532-4149
Türkiye


Saliha B. KURT Bu kişi benim
CANAKKALE ONSEKIZ MART UNIVERSITY
0000-0003-0346-441X
Türkiye


Betül ARİ>
CANAKKALE ONSEKIZ MART UNIVERSITY
0000-0003-3557-3055
Türkiye


Sahin DEMIRCI Bu kişi benim
CANAKKALE ONSEKIZ MART UNIVERSITY
0000-0001-7083-1481
Türkiye


Selehattin YILMAZ>
CANAKKALE ONSEKIZ MART UNIVERSITY
0000-0003-4607-3523
Andorra

Yayımlanma Tarihi 7 Kasım 2020
Yayınlandığı Sayı Yıl 2020, Cilt 4, Sayı 4

Kaynak Göster

APA Yanık, S. , B. Kurt, S. , Ari, B. , Demırcı, S. & Yılmaz, S. (2020). DEVELOPMENT OF ELECTROCHEMICAL SENSORS FOR QUANTITATIVE ANALYSIS OF METHYLDOPA AT MODIFIED-GCE AND PGE ELECTRODES BY VOLTAMMETRY . Journal of Scientific Perspectives , 4 (4) , 223-236 . Retrieved from https://dergipark.org.tr/tr/pub/jsp/issue/57837/827197