Kiral Cu II -Schiff Bazı Kompleksinin Hazırlanması ve Asimetrik Kataliz İçin Uygulaması

Yıl 2018, Cilt: 8 Sayı: 1, 151 - 155, 01.01.2018

Leman Alkan

Öz

Kiral bakır II -Schiff bazı kompleksi L-Fenilalanin’ den çıkılarak enantiyoseçimli Henry tepkimesi için sentezlendi. Çeşitli kiral β-nitroalkoller iyi verim %76 ya kadar ve yüksek enantiyoseçicilikle %90 a kadar optimize edilmiş tepkime koşulları altında elde edildi

Anahtar Kelimeler

Asimetrik Henry tepkimesi, Schiff bazı, Kiral bakır II katalizörü, β-nitroalkol

Preparation Of A Chiral Cu II -Schiff Base Complex And Application For Asymmetric Catalysis

Öz

A chiral copper II -Schiff base complex was synthesized from L-Phenylalanine for the enantioselective Henry reaction. A variety of chiral β-nitroalcohols were obtained in good yield up to 76% with high enantioselectivities up to 90% ee under the optimized reaction conditions.

Anahtar Kelimeler

Asymmetric Henry Reaction, Schiff Base, Chiral Copper II Catalyst, β-nitroalcohol

Kaynakça

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