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Laktoz Türevi Olarak Laktobionik Asit

Yıl 2015, Cilt: 5 Sayı: 1, 56 - 59, 01.01.2015

Özge Duygu Okur

Öz

Laktoz gıda endüstrisinde yüksek değerli türevlerinin üretiminde öncül madde olarak kullanılmaktadır. Laktozun enzimatik, mikrobiyal veya kimyasal modifi kasyonu ile elde edilen laktobionik asit üretimi bazı önemli gelişmeler göstermektedir. Bu derlemede, biyoaktif bileşik olarak potansiyel uygulamaları olan laktobionik asitin temel özellikleri, üretim metotları ve uygulamaları değerlendirilecektir

Anahtar Kelimeler

Laktobionik asit Gıda Laktoz

Kaynakça

  • Alonso, S., Rendueles, M., Diaz, M. 2011. Effi cient lactobionic acid production from whey by Pseudomonas taetrolens under pH-shift conditions. Bioresour. Technol. 102: 9730-9736.
  • Aoun, SB., Bang, GS., Koga, T., Nonaka, Y., Sotomura, T., Taniguchi, I. 2003. Electrocatalytic oxidation of sugars on silver-UPD single crystal gold electrodes in alkaline solutions. Electrochem. Commun. 5: 317-320.
  • Colwell, NS., Grupe, MJ., Tollefsen, DM. 1999. Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions. BBA-Protein Struct M. 1431: 148-156.
  • da Silva, EAB., Pedruzzi, I., Rodrigues, AE. 2011. Simulated moving bed technology to improve the yield of the biotechnological production of lactobionic acid and sorbitol. Adsorption. 17: 145-158.
  • Fischer, E., Meyer, J. 1889. Oxydation des milchzuckers. Ber Dtsch Chem Ges. 22: 361-364.
  • Gänzle, M.G., Haase, G., Jelen, P. 2008. Lactose: crystallization, hydrolysis and value-added derivatives. Int. Dairy J., 18: 685-694.
  • Gänzle, MG. 2011. Lactose and oligosaccharides-lactose: derivatives. In JW. Fuquay, PF. Fox, & PLH. McSweeney (Eds.), Encyclopedia of Dairy Sciences (2nd ed.). (pp. 202- 208) San Diego, CA, USA: Academic Press.
  • Gänzle, MG. 2012. Enzymatic synthesis of galacto- oligosaccharides and other lactose derivatives (hetero- oligosaccharides) from lactose. Int Dairy J. 22: 116-122.
  • Gerling, KG. 1998. Large scale production of lactobionic acid-use and new applications. In Whey: Proceedings of the second international whey conference (pp. 251-261). Chicago, IL, USA: International Dairy Federation.
  • Gutiérrez, LF., Hamoudi, S., Belkacemi, K. 2011. Selective production of lactobionic acid by aerobic oxidation of lactose over gold crystallites supported on mesoporous silica. Appl Catal A-Gen, 402: 94-103.
  • Gutiérrez, LF., Hamoudi, S., Belkacemi, K. 2012. Lactobionic acid: A high value-added lactose derivative for food and pharmaceutical applications. Int Dairy J. 26: 103-111.
  • Isbell, H.S. 1934. Process for the preparation of calcium lactobionate. US Patent 1.980.996.
  • Karim-Nezhad G., Hasanzadeh M., Saghatforoush L., Shadjou N., Earshad S., Khalilzadeh, B. 2009. Kinetic study of electrocatalytic oxidation of carbohydrates on cobalt hydroxide modifi ed glassy carbon electrode. J Brazıl Chem Soc. 20: 141-151.
  • Kokoh, KB., Alonso-Vante, N. 2006. Electrocatalytic oxidation of lactose on gold nanoparticle modifi ed carbon in carbonate buffer. J Appl Electrochem. 36: 147-151.
  • Maki-Arvela, P., Murzina, EV., Campo, B., Heikkila, T., Leino, AR., Kordas, K., Wolf, D., Tokarev, AV., Murzin, DY. 2010. The effect of palladium dispersion and promoters on lactose oxidation kinetics. Res Chem Intermedıat, 36: 423- 442.
  • Murzina, EV., Tokarev, AV., Kordas, K., Karhu, H., Mikkola, JP., Murzin, DY. 2008. D-Lactose oxidation over gold catalysts. Catal Today, 131: 385-392.
  • Nakano, H., Kiryu, T., Kiso, T., Murakami, H. 2010. Biocatalytic production of lactobionic acid. In CT Hou, & JF Shaw (Eds.), Biocatalysis and Biomolecular Engineering (pp. 391-404). Hoboken, NJ, USA: John Wiley & Sons, Inc.
  • Nielsen, PM. 2009. Meat based food product comprising lactobionic acid. US Patent 20090214752.
  • Nordkvist, M., Nielsen, PM., Villadsen, J. 2007. Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: kinetics and operational stability. Bıotechnol Bıoeng., 97: 694-707.
  • Oskarsson, H., Frankenberg, M., Annerling, A., Holmberg, K. 2007. Adsorption of novel alkylaminoamide sugar surfactants at tailor-made surfaces. J Surfactants Deterg., 10: 41-52.
  • Panesar, PS., Kumari, S. 2011. Lactulose: production, purifi cation and potential applications. Bıotechnol Adv., 29: 940-948.
  • Pedruzzi, I., Borges da Silva, EA., Rodrigues, AE. 2011. Production of lactobionic acid and sorbitol from lactose/ fructose substrate using GFOR/GL enzymes from Zymomonas mobilis cells: a kinetic study. Enzyme Mıcrob Tech, 49: 183-191.
  • Playne, M.J., Crittenden, RG. 2009. Galacto-oligosaccharides and other products derived from lactose. In PLH. McSweeney, & PF Fox (Eds.), Lactose, water, salts and minor constituents (3rd ed.). Advanced Dairy Chemistry, Vol. 3 (pp. 121-201) New York, NY, USA: Springer.
  • Raake, W., Klauser, RJ., Elling, H., Meinetsberger, E. 1989. Anticoagulant and antithrombotic properties of synthetic sulfated bis-lactobionic acid-amides. Thromb Res., 56: 719- 730.
  • Saarela, M., Hallamaa, K., Mattila-Sandholm, T., Mättö, J. 2003. The effect of lactose derivatives lactulose, lactitol and lactobionic acid on the functional and technological properties of potentially probiotic Lactobacillus strains. Int. Dairy J., 13: 291-302.
  • Tokarev, AV., Murzina, EV., Kuusisto, J., Mikkola, JP., Eranen, K., Murzin, DY. 2006. Kinetic behaviour of electrochemical potential in three-phase heterogeneous catalytic oxidation reactions. J Mol Catal A-Chem., 255: 199-208.
  • Tokarev, AV., Murzina, EV., Mikkola, JP., Kuusisto, J., Kustov, LM., Murzin, DY. 2007. Application of in situ catalyst potential measurements for estimation of reaction performance: lactose oxidation over Au and Pd catalysts. Chem. Eng. J., 134: 153-161.
  • Tokarev, AV., Murzina, EV., Seelam, PK., Kumar, N., Murzin, DY. 2008. Infl uence of surface acidity in lactose oxidation over supported Pd catalysts. Mıcropor. Mesopor. Mat., 113: 122-131.
  • Torres, DPM., Goncalves, MDF., Teixeira, JA., Rodrigues, LR. 2010. Galacto-oligosaccharides: production, properties, applications, and signifi cance as prebiotics. Compr. Rev. Food Sci. F., 9: 438-454.
  • Zhang, J., Li, C., Xue, ZY., Cheng, HW., Huang, FW., Zhuo, RX. 2011. Fabrication of lactobionic-loaded chitosan microcapsules as potential drug carriers targeting the liver. Acta Bıomater., 7: 1665-1673.

Lactobionic Acid as Lactose Derivative

Yıl 2015, Cilt: 5 Sayı: 1, 56 - 59, 01.01.2015

Özge Duygu Okur

Öz

Laktoz gıda endüstrisinde yüksek değerli türevlerinin üretiminde öncül madde olarak kullanılmaktadır. Laktozun enzimatik, mikrobiyal veya kimyasal modifi kasyonu ile elde edilen laktobionik asit üretimi bazı önemli gelişmeler göstermektedir. Bu derlemede, biyoaktif bileşik olarak potansiyel uygulamaları olan laktobionik asitin temel özellikleri, üretim metotları ve uygulamaları değerlendirilecektir.

Anahtar Kelimeler

Laktobionik asit Gıda Laktoz

Kaynakça

  • Alonso, S., Rendueles, M., Diaz, M. 2011. Effi cient lactobionic acid production from whey by Pseudomonas taetrolens under pH-shift conditions. Bioresour. Technol. 102: 9730-9736.
  • Aoun, SB., Bang, GS., Koga, T., Nonaka, Y., Sotomura, T., Taniguchi, I. 2003. Electrocatalytic oxidation of sugars on silver-UPD single crystal gold electrodes in alkaline solutions. Electrochem. Commun. 5: 317-320.
  • Colwell, NS., Grupe, MJ., Tollefsen, DM. 1999. Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions. BBA-Protein Struct M. 1431: 148-156.
  • da Silva, EAB., Pedruzzi, I., Rodrigues, AE. 2011. Simulated moving bed technology to improve the yield of the biotechnological production of lactobionic acid and sorbitol. Adsorption. 17: 145-158.
  • Fischer, E., Meyer, J. 1889. Oxydation des milchzuckers. Ber Dtsch Chem Ges. 22: 361-364.
  • Gänzle, M.G., Haase, G., Jelen, P. 2008. Lactose: crystallization, hydrolysis and value-added derivatives. Int. Dairy J., 18: 685-694.
  • Gänzle, MG. 2011. Lactose and oligosaccharides-lactose: derivatives. In JW. Fuquay, PF. Fox, & PLH. McSweeney (Eds.), Encyclopedia of Dairy Sciences (2nd ed.). (pp. 202- 208) San Diego, CA, USA: Academic Press.
  • Gänzle, MG. 2012. Enzymatic synthesis of galacto- oligosaccharides and other lactose derivatives (hetero- oligosaccharides) from lactose. Int Dairy J. 22: 116-122.
  • Gerling, KG. 1998. Large scale production of lactobionic acid-use and new applications. In Whey: Proceedings of the second international whey conference (pp. 251-261). Chicago, IL, USA: International Dairy Federation.
  • Gutiérrez, LF., Hamoudi, S., Belkacemi, K. 2011. Selective production of lactobionic acid by aerobic oxidation of lactose over gold crystallites supported on mesoporous silica. Appl Catal A-Gen, 402: 94-103.
  • Gutiérrez, LF., Hamoudi, S., Belkacemi, K. 2012. Lactobionic acid: A high value-added lactose derivative for food and pharmaceutical applications. Int Dairy J. 26: 103-111.
  • Isbell, H.S. 1934. Process for the preparation of calcium lactobionate. US Patent 1.980.996.
  • Karim-Nezhad G., Hasanzadeh M., Saghatforoush L., Shadjou N., Earshad S., Khalilzadeh, B. 2009. Kinetic study of electrocatalytic oxidation of carbohydrates on cobalt hydroxide modifi ed glassy carbon electrode. J Brazıl Chem Soc. 20: 141-151.
  • Kokoh, KB., Alonso-Vante, N. 2006. Electrocatalytic oxidation of lactose on gold nanoparticle modifi ed carbon in carbonate buffer. J Appl Electrochem. 36: 147-151.
  • Maki-Arvela, P., Murzina, EV., Campo, B., Heikkila, T., Leino, AR., Kordas, K., Wolf, D., Tokarev, AV., Murzin, DY. 2010. The effect of palladium dispersion and promoters on lactose oxidation kinetics. Res Chem Intermedıat, 36: 423- 442.
  • Murzina, EV., Tokarev, AV., Kordas, K., Karhu, H., Mikkola, JP., Murzin, DY. 2008. D-Lactose oxidation over gold catalysts. Catal Today, 131: 385-392.
  • Nakano, H., Kiryu, T., Kiso, T., Murakami, H. 2010. Biocatalytic production of lactobionic acid. In CT Hou, & JF Shaw (Eds.), Biocatalysis and Biomolecular Engineering (pp. 391-404). Hoboken, NJ, USA: John Wiley & Sons, Inc.
  • Nielsen, PM. 2009. Meat based food product comprising lactobionic acid. US Patent 20090214752.
  • Nordkvist, M., Nielsen, PM., Villadsen, J. 2007. Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: kinetics and operational stability. Bıotechnol Bıoeng., 97: 694-707.
  • Oskarsson, H., Frankenberg, M., Annerling, A., Holmberg, K. 2007. Adsorption of novel alkylaminoamide sugar surfactants at tailor-made surfaces. J Surfactants Deterg., 10: 41-52.
  • Panesar, PS., Kumari, S. 2011. Lactulose: production, purifi cation and potential applications. Bıotechnol Adv., 29: 940-948.
  • Pedruzzi, I., Borges da Silva, EA., Rodrigues, AE. 2011. Production of lactobionic acid and sorbitol from lactose/ fructose substrate using GFOR/GL enzymes from Zymomonas mobilis cells: a kinetic study. Enzyme Mıcrob Tech, 49: 183-191.
  • Playne, M.J., Crittenden, RG. 2009. Galacto-oligosaccharides and other products derived from lactose. In PLH. McSweeney, & PF Fox (Eds.), Lactose, water, salts and minor constituents (3rd ed.). Advanced Dairy Chemistry, Vol. 3 (pp. 121-201) New York, NY, USA: Springer.
  • Raake, W., Klauser, RJ., Elling, H., Meinetsberger, E. 1989. Anticoagulant and antithrombotic properties of synthetic sulfated bis-lactobionic acid-amides. Thromb Res., 56: 719- 730.
  • Saarela, M., Hallamaa, K., Mattila-Sandholm, T., Mättö, J. 2003. The effect of lactose derivatives lactulose, lactitol and lactobionic acid on the functional and technological properties of potentially probiotic Lactobacillus strains. Int. Dairy J., 13: 291-302.
  • Tokarev, AV., Murzina, EV., Kuusisto, J., Mikkola, JP., Eranen, K., Murzin, DY. 2006. Kinetic behaviour of electrochemical potential in three-phase heterogeneous catalytic oxidation reactions. J Mol Catal A-Chem., 255: 199-208.
  • Tokarev, AV., Murzina, EV., Mikkola, JP., Kuusisto, J., Kustov, LM., Murzin, DY. 2007. Application of in situ catalyst potential measurements for estimation of reaction performance: lactose oxidation over Au and Pd catalysts. Chem. Eng. J., 134: 153-161.
  • Tokarev, AV., Murzina, EV., Seelam, PK., Kumar, N., Murzin, DY. 2008. Infl uence of surface acidity in lactose oxidation over supported Pd catalysts. Mıcropor. Mesopor. Mat., 113: 122-131.
  • Torres, DPM., Goncalves, MDF., Teixeira, JA., Rodrigues, LR. 2010. Galacto-oligosaccharides: production, properties, applications, and signifi cance as prebiotics. Compr. Rev. Food Sci. F., 9: 438-454.
  • Zhang, J., Li, C., Xue, ZY., Cheng, HW., Huang, FW., Zhuo, RX. 2011. Fabrication of lactobionic-loaded chitosan microcapsules as potential drug carriers targeting the liver. Acta Bıomater., 7: 1665-1673.
Toplam 30 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Research Article
Yazarlar

Özge Duygu Okur Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 5 Sayı: 1

Kaynak Göster

APA Okur, Ö. D. (2015). Laktoz Türevi Olarak Laktobionik Asit. Karaelmas Fen Ve Mühendislik Dergisi, 5(1), 56-59.
AMA Okur ÖD. Laktoz Türevi Olarak Laktobionik Asit. Karaelmas Fen ve Mühendislik Dergisi. Ocak 2015;5(1):56-59.
Chicago Okur, Özge Duygu. “Laktoz Türevi Olarak Laktobionik Asit”. Karaelmas Fen Ve Mühendislik Dergisi 5, sy. 1 (Ocak 2015): 56-59.
EndNote Okur ÖD (01 Ocak 2015) Laktoz Türevi Olarak Laktobionik Asit. Karaelmas Fen ve Mühendislik Dergisi 5 1 56–59.
IEEE Ö. D. Okur, “Laktoz Türevi Olarak Laktobionik Asit”, Karaelmas Fen ve Mühendislik Dergisi, c. 5, sy. 1, ss. 56–59, 2015.
ISNAD Okur, Özge Duygu. “Laktoz Türevi Olarak Laktobionik Asit”. Karaelmas Fen ve Mühendislik Dergisi 5/1 (Ocak 2015), 56-59.
JAMA Okur ÖD. Laktoz Türevi Olarak Laktobionik Asit. Karaelmas Fen ve Mühendislik Dergisi. 2015;5:56–59.
MLA Okur, Özge Duygu. “Laktoz Türevi Olarak Laktobionik Asit”. Karaelmas Fen Ve Mühendislik Dergisi, c. 5, sy. 1, 2015, ss. 56-59.
Vancouver Okur ÖD. Laktoz Türevi Olarak Laktobionik Asit. Karaelmas Fen ve Mühendislik Dergisi. 2015;5(1):56-9.