Çam Balı Takviyeli Kitosan Esaslı Aktif Filmler

Yıl 2023, Cilt: 13 Sayı: 1, 62 - 71, 30.06.2023

Özge Kuyucak , Pınar Terzioğlu , Yusuf Sıcak

Öz

Yara örtüleri, özellikle kronik iyileşmeyen yaraların iyileşmesini hızlandırmada ve enfeksiyonu önlemede önemli rol oynamaktadır. Bal, biyouyumlu ve biyoaktiviteye sahip olduğu için modern klinik yara bakımı uygulamalarında değerlendirilmektedir. Son yıllarda, bal/ polimer hibrid malzemelerin yara iyileşme sürecini destekleyen terapötik özelliğe sahip ideal adaylar olabileceği düşünülmektedir. Bu çalışmada, çam balı (% 0-12.5) içeren kitosan esaslı filmler çözelti döküm yöntemi ile geliştirildi. Filmlerin morfolojisi ve yapısal özellikleri sırasıyla taramalı elektron mikroskobu ve Fourier Dönüşümlü Kızıl Ötesi Spektroskopisi (FTIR) ile belirlendi. Filmlerin antioksidan aktivitesi dört farklı metot ile belirlendi. FTIR spektrumları çam balının kitosan filmlere başarıyla dahil edildiğini gösterdi. Bal ilavesi filmlerin antioksidan aktivitesini arttırdı. Bu sonuçlar, çam balı içeren kitosan filmlerin yaraları tedavi etmek için umut verici adaylar olduğunu göstermektedir.

Anahtar Kelimeler

Bal, Kitosan film, Biyoaktivite

Destekleyen Kurum

TÜBİTAK 2209-B,

Proje Numarası

Başvuru numarası: 1139B411900084

Teşekkür

Bu çalışma TÜBİTAK 2209-B Üniversite Öğrencileri Araştırma Projeleri Destek Programı kapsamında desteklenmiştir (Başvuru numarası: 1139B411900084). Desteklerinden dolayı TÜBİTAK’a teşekkür ederiz.

Pine Honey Incorporated Chitosan Based Active Fims

Öz

Wound dressings play an important role in accelerating the healing of chronic non-healing wounds and preventing infection. Honey is evaluated in modern clinical wound care applications due to having biocompatible and bioactivity. In recent years, it is thought that honey / polymer hybrid materials can be ideal candidates with therapeutic properties that support the wound healing process. In this study, chitosan based films containing pine honey (0-12.5%) were developed by solution casting method. The morphology and structural properties of the films were determined by scanning electron microscopy and Fourier Transform Infrared Spectroscopy (FTIR), respectively. The antioxidant activity of the films was determined by four different methods. The FTIR spectra showed that pine honey was successfully incorporated into chitosan films. The addition of honey increased the antioxidant activity of the films. These results show that chitosan films containing pine honey are promising candidates for treating wounds.

Anahtar Kelimeler

Honey, Chitosan film, Bioactivity

Proje Numarası

Başvuru numarası: 1139B411900084

Kaynakça

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