Effect of Localization of Coronary Artery Lesions on Total Perfusion Deficit in Myocardial Perfusion Scintigraphy

Yıl 2018, Cilt: 21 Sayı: 3, 181 - 186, 02.12.2018

Cem Doğan , Zübeyde Bayram Ferahnaz Çınaral Abdülkadir Uslu Rezzan Deniz Acar Çağatay Önal Murat Çap Büşra Güvendi Tuba Unkun Ahmet Karaduman Aykun Hakgör Özgür Yaşar Akbal Cihangir Kaymaz Nihal Özdemir

Öz

Introduction: In the present study, we analyzed patients with stable coronary artery disease (SCAD) by quantitative myocardial perfusion scintigraphy and evaluated the effect of different coronary lesion locations on total perfusion deficit (TPD).

Patients and Methods: A total of 133 consecutive patients with SCAD who underwent myocardial perfusion imaging single photon emission computed tomography (SPECT) and conventional coronary angiography according to SPECT results were included in the study. TPD was used as the automated quantification variable.

Results: Of the patients, 61 had significant coronary artery disease, and 72 had normal coronary arteries. For the normal, left anterior descending artery (LAD), circumflex artery (CX), and right coronary artery (RCA) groups, the median values were 7% vs. 11% vs. 10% vs. 9%, 4% vs. 6% vs. 7% vs. 4%, and 3% vs. 5% vs. 6% vs. 3% for stress TPD (sTPD), rest TPD (rTPD), and ischemic TPD (iTPD), respectively. There was no statistically significant difference in quantitative analysis (sTPD, rTPD, and iTPD) between the LAD, CX, and RCA groups (p> 0.05).

Conclusion: TPD obtained by quantitative analysis method can be used for all coronary artery lesion location.

Anahtar Kelimeler

Stable coronary artery disease, total perfusion deficit, SPECT

Miyokart Perfüzyon Sintigrafisinde Koroner Arter Lezyonlarının Lokalizasyonunun Total Perfüzyon Defekti Üzerine Etkisi

Öz

Giriş: Bu çalışmada kantitatif miyokart perfüzyon sintigrafisi ile stabil koroner arter hastalığı olan hastaları inceledik ve farklı koroner lezyon lokasyonlarının total perfüzyon defekti üzerine olan etkisini değerlendirdik.

Hastalar ve Yöntem: Stabil koroner arter hastalığı olan miyokardiyal perfüzyon görüntüleme-SPECT yapılan ve SPECT sonuçlarına göre konvansiyonel koroner anjiyografiye alınmış 133 ardışık hasta çalışmaya alındı. Kantitatif inceleme değişkeni olarak total perfüzyon defekti (TPD) kullanıldı.

Bulgular: Atmış bir hastada anlamlı koroner arter hastalığı ve 72 hastada normal koroner arter vardı. Normal, LAD, CX ve RCA grupları için medyan değerler sTPD (sırasıyla %7, %11, %10, %10), rTPD (sırasıyla %4, %6, %7, %4,) ve iTPD ( sırasıyla %3, %5, %6, %3) idi. Kantitatif analizde (sTPD, rTPD ve iTPD) LAD, CX ve RCA grupları arasında istatistiksel olarak anlamlı fark yoktu (p> 0.05).

Sonuç: Kantitatif analiz yöntemiyle elde edilen total perfüzyon defisiti tüm koroner arter hastalığı lokalizasyonları için kullanılabilir.

Anahtar Kelimeler

Kararlı koroner arter hastalığı, total perfüzyon defisiti, SPECT

Kaynakça

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