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Atriyoventriküler Nodal Reentran ve Atriyoventriküler Reentran Taşikardili Hastaların Ayırıcı Tanısında Epikardiyal Yağ Kalınlığı Kullanılabilir

Yıl 2019, Cilt: 22 Sayı: 3, 188 - 192, 24.12.2019

Öz

Giriş: Epikardiyal yağ kalınlığı (EYK) aritmik olaylarda rolü olduğu bilinmektedir. Biz bu çalışmada supraventriküler aritmilerin ayırıcı tanısında EYK’nın kullanılabilirliğini araştırdık.

Hastalar ve Yöntem: Kliniğimize çarpıntı şikayeti ile başvuran veya yüzeyel EKG’de SVT tanısı olan ve elektrofizyolojik çalışma (EFÇ) yapılmış 259 hasta dahil edildi. Hastaların demografik, ekokardiyografik verileri ile birlikte EFÇ ile belirlenmiş tanıları kaydedildi.

Bulgular: Çalışmamıza; 88 adet kontrol, 95 adet AVNRT ve 66 adet AVRT’li hastayı dahil ettik. TTE verileri karşılaştırıldığında ise; epikardiyal yağ kalınlığı (p= 0.001) AVRT’li hasta grubunda anlamlı oranda artmış olarak tespit edildi. Binominal lojistik regresyon analizinde EYK bağımsız prediktor olarak tespit edildi (OR:2.2 %95 GA: 1.456-5.478, p< 0.001). Yapılan ROC analizinde, EYK kesim değeri 15 mm olarak alındığında %77.3 sensitivite ve %58.9 spesifite ile AVNRT, AVRT ayrımının yapılabileceği tespit edildi.

Sonuç: Epikardiyal yağ kalınlığı AVRT’li hastalarda artmış olabilir ve ayırıcı tanıda kullanılabilir.

Kaynakça

  • 1. Blomstrom-Lundqvist C, Scheinman MM, Aliot EM, Alpert JS, Calkins H, Camm AJ, et al. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients with Supraventricular Arrhythmias). Circulation 2003;108:1871-909.
  • 2. Baine WB, Yu W, Weis KA. Trends and outcomes in the hospitalization of older Americans for cardiac conduction disorders or arrhythmias, 1991-1998. J Am Geriatr Soc 2001;49:763-70.
  • 3. Jackman WM, Beckman KJ, McClelland JH, Wang X, Friday KJ, Roman CA, et al. Treatment of supraventricular tachycardia due to atrioventricular nodal reentry, by radiofrequency catheter ablation of slow-pathway conduction. N Engl J Med 1992;327:313-8.
  • 4. Haissaguerre M, Gaita F, Fischer B, Commenges D, Montserrat P, d’Ivernois C, et al. Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulation 1992;85:2162-75.
  • 5. Ezhumalai B, Satheesh S, Anantha A, Pakkirisamy G, Balachander J, Selvaraj RJ. Coronary sinus diameter by echocardiography to differentiate atrioventricular nodal reentrant tachycardia from atrioventricular reentrant tachycardia. Cardiol J 2014;21:273-8.
  • 6. Okumura Y, Watanabe I, Yamada T, Ohkubo K, Masaki R, Sugimura H, et al. Comparison of coronary sinus morphology in patients with and without atrioventricular nodal reentrant tachycardia by intracardiac echocardiography. J Cardiovasc Electrophysiol 2004;15:269-73.
  • 7. Senturk SE, Icen YK, Koc AS, Donmez Y, Baykan AO, et al. Evaluation of coronary sinus morphology by three-dimensional transthoracic echocardiography in patients undergoing electrophysiological study. J Arrhythm 2018;34:626-31.
  • 8. Ong MG, Lee PC, Tai CT, Lin YJ, Lee KT, et al. Coronary sinus morphology in different types of supraventricular tachycardias. J Interv Card Electrophysiol 2006;15:21-6.
  • 9. Samanta R, Pouliopoulos J, Thiagalingam A, Kovoor P. Role of adipose tissue in the pathogenesis of cardiac arrhythmias. Heart Rhythm 2016;13:311-20.
  • 10. Soeki T, Sata M. Role of epicardial adipose tissue in atrial fibrillation. Circ J 2012;76:2738-9.
  • 11. Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Arafat H, et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003;108:2460-6.
  • 12. Iacobellis G, Corradi D, Sharma AM. Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart. Nat Clin Pract Cardiovasc Med 2005;2:536-43.
  • 13. Jeong JW, Jeong MH, Yun KH, Oh SK, Park EM, Kim YK, et al. Echocardiographic epicardial fat thickness and coronary artery disease. Circ J 2007;71:536-9.
  • 14. Karastergiou K, Fried SK. Multiple adipose depots increase cardiovascular risk via local and systemic effects. Curr Atheroscler Rep 2013;15:361.
  • 15. Wong CX, Ganesan AN, Selvanayagam JB. Epicardial fat and atrial fibrillation: current evidence, potential mechanisms, clinical implications, and future directions. Eur Heart J 2017;38:1294-302.
  • 16. Josephson ME, Scharf DL, Kastor JA, Kitchen JG. Atrial endocardial activation in man. Electrode catheter technique of endocardial mapping. Am J Cardiol 1977;39:972-81.
  • 17. Becker AE. Atrial anatomy: relationship to atrial flatter. In: Waldo AL, Touboul P (eds). Atrial Flutter: Advances in Mecahnism and Management. Armonk, NY: Futura Publishing, 1996:13-9.
  • 18. Cipoletta L, Acosta J, Mont L, Berruezo A. Posterior coronary vein as the substrate for an epicardial accessory pathway. Indian Pacing Electrophysiol J 2013;13:142-7.
  • 19. Scanavacca MI, Sternick EB, Pisani C, Lara S, Hardy C, d’Ávila A, et al. Accessory atrioventricular pathways refractory to catheter ablation: role of percutaneous epicardial approach. Circ Arrhythm Electrophysiol 2015;8:128-36.

Epicardial Fat Thickness May be Used in the Differential Diagnosis of Atrioventricular Nodal Re-entrant and Atrioventricular Re-entrant Tachycardia

Yıl 2019, Cilt: 22 Sayı: 3, 188 - 192, 24.12.2019

Öz

Introduction: Epicardial fat thickness (EFT) is known to play a role in arrhythmic events. In this study, we analysed the feasibility of using EFT in the differential diagnosis of supraventricular arrhythmias.

Patients and Methods: A total of 259 patients were included in the study, all of whom had applied to our outpatient clinic with palpitation complaints or who had been diagnosed with SVT by surface electrocardiogram (ECG) and had undergone complete electrophysiological studies (EPS). The patients’ demographic and echocardiography data along with their EPS-based diagnoses were recorded.

Results: We included 88 control patients, 95 atrioventricular nodal re-entrant tachycardia (AVNRT) patients and 65 atrioventricular re-entrant tachycardia (AVRT) patients. Transthoracic echocardiography (TTE) data showed that the EFT in AVRT group was increased significantly (p= 0.001). In multinomial logistic regression analysis, EFT was identified as an independent predictor (OR:2.2 95% CI: 1.456-5.478, p< 0.001). receiver operating characteristic analysis showed that, when EFT is given at 15 mm, AVNRT and AVRT differentiation can be performed with 77.3% sensitivity and 58.9% specificity.

Conclusion: EFT may be increased in patients with AVRT and can be used in differential diagnoses.

Kaynakça

  • 1. Blomstrom-Lundqvist C, Scheinman MM, Aliot EM, Alpert JS, Calkins H, Camm AJ, et al. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients with Supraventricular Arrhythmias). Circulation 2003;108:1871-909.
  • 2. Baine WB, Yu W, Weis KA. Trends and outcomes in the hospitalization of older Americans for cardiac conduction disorders or arrhythmias, 1991-1998. J Am Geriatr Soc 2001;49:763-70.
  • 3. Jackman WM, Beckman KJ, McClelland JH, Wang X, Friday KJ, Roman CA, et al. Treatment of supraventricular tachycardia due to atrioventricular nodal reentry, by radiofrequency catheter ablation of slow-pathway conduction. N Engl J Med 1992;327:313-8.
  • 4. Haissaguerre M, Gaita F, Fischer B, Commenges D, Montserrat P, d’Ivernois C, et al. Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulation 1992;85:2162-75.
  • 5. Ezhumalai B, Satheesh S, Anantha A, Pakkirisamy G, Balachander J, Selvaraj RJ. Coronary sinus diameter by echocardiography to differentiate atrioventricular nodal reentrant tachycardia from atrioventricular reentrant tachycardia. Cardiol J 2014;21:273-8.
  • 6. Okumura Y, Watanabe I, Yamada T, Ohkubo K, Masaki R, Sugimura H, et al. Comparison of coronary sinus morphology in patients with and without atrioventricular nodal reentrant tachycardia by intracardiac echocardiography. J Cardiovasc Electrophysiol 2004;15:269-73.
  • 7. Senturk SE, Icen YK, Koc AS, Donmez Y, Baykan AO, et al. Evaluation of coronary sinus morphology by three-dimensional transthoracic echocardiography in patients undergoing electrophysiological study. J Arrhythm 2018;34:626-31.
  • 8. Ong MG, Lee PC, Tai CT, Lin YJ, Lee KT, et al. Coronary sinus morphology in different types of supraventricular tachycardias. J Interv Card Electrophysiol 2006;15:21-6.
  • 9. Samanta R, Pouliopoulos J, Thiagalingam A, Kovoor P. Role of adipose tissue in the pathogenesis of cardiac arrhythmias. Heart Rhythm 2016;13:311-20.
  • 10. Soeki T, Sata M. Role of epicardial adipose tissue in atrial fibrillation. Circ J 2012;76:2738-9.
  • 11. Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Arafat H, et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003;108:2460-6.
  • 12. Iacobellis G, Corradi D, Sharma AM. Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart. Nat Clin Pract Cardiovasc Med 2005;2:536-43.
  • 13. Jeong JW, Jeong MH, Yun KH, Oh SK, Park EM, Kim YK, et al. Echocardiographic epicardial fat thickness and coronary artery disease. Circ J 2007;71:536-9.
  • 14. Karastergiou K, Fried SK. Multiple adipose depots increase cardiovascular risk via local and systemic effects. Curr Atheroscler Rep 2013;15:361.
  • 15. Wong CX, Ganesan AN, Selvanayagam JB. Epicardial fat and atrial fibrillation: current evidence, potential mechanisms, clinical implications, and future directions. Eur Heart J 2017;38:1294-302.
  • 16. Josephson ME, Scharf DL, Kastor JA, Kitchen JG. Atrial endocardial activation in man. Electrode catheter technique of endocardial mapping. Am J Cardiol 1977;39:972-81.
  • 17. Becker AE. Atrial anatomy: relationship to atrial flatter. In: Waldo AL, Touboul P (eds). Atrial Flutter: Advances in Mecahnism and Management. Armonk, NY: Futura Publishing, 1996:13-9.
  • 18. Cipoletta L, Acosta J, Mont L, Berruezo A. Posterior coronary vein as the substrate for an epicardial accessory pathway. Indian Pacing Electrophysiol J 2013;13:142-7.
  • 19. Scanavacca MI, Sternick EB, Pisani C, Lara S, Hardy C, d’Ávila A, et al. Accessory atrioventricular pathways refractory to catheter ablation: role of percutaneous epicardial approach. Circ Arrhythm Electrophysiol 2015;8:128-36.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Orijinal Araştırmalar
Yazarlar

Atilla Bulut 0000-0001-8178-4027

Yayımlanma Tarihi 24 Aralık 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 22 Sayı: 3

Kaynak Göster

Vancouver Bulut A. Epicardial Fat Thickness May be Used in the Differential Diagnosis of Atrioventricular Nodal Re-entrant and Atrioventricular Re-entrant Tachycardia. Koşuyolu Heart Journal. 2019;22(3):188-92.