Araştırma Makalesi
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Yıl 2022, Cilt: 25 Sayı: 2, 127 - 131, 20.08.2022

Öz

Kaynakça

  • 1. Pahlm O, Wagner GS. QRS, ST and T changes of acute transmural myocardial ischemia: Overview editorial. J Electrocardiol 2014;47(4):397-401. [Crossref]
  • 2. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD; Joint ESC/ACCF/AHA/WHF Task Force for Universal Definition of Myocardial Infarction; Third universal definition of myocardial infarction. J Am Coll Cardiol 2012;60(16):1581-98. [Crossref]
  • 3. Bateman TM, Czer LS, Gray RJ, Maddahi J, Raymond MJ, Geft IL, et al. Transient pathologic Q waves during acute ischemic events: An electrocardiographic correlate of stunned but viable myocardium. Am Heart J 1983;106(6):1421-6. [Crossref]
  • 4. Kochav JD, Okin PM, Wilson S, Afroz A, Renilla A, Weinsaft JW. Usefulness of Q wave area for threshold-based stratification of global left ventricular myocardial infarct size. Am J Cardiol 2013;112(2):174-80. [Crossref]
  • 5. Michael MA, El Masry H, Khan BR, Das MK. Electrocardiographic signs of remote myocardial infarction. Prog Cardiovasc Dis 2007;50(3):198-208. [Crossref]
  • 6. Antman EM, McCabe CH, Gurfinkel EP, Turpie AG, Bernink PJ, Salein D, et al. Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q wave myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) 11B trial. Circulation 1999;100(15):1593-601. [Crossref]
  • 7. Karakuş A, Uğuz B. Prognostic value of the Selvester QRS score for re-hospitalization in patients with ischemic heart failure. J Surg Med 2020;4(12):1165-8. [Crossref]
  • 8. Jaarsma W, Visser CA, van Eenige MJ, Roos JP. Left ventricular wall motion with and without Q wave disappearance after acute myocardial infarction. Am J Cardiol 1987;59(6):516-8. [Crossref]
  • 9. Coll S, Betriu A, de Flores T, Roig E, Sanz G, Mont L, et al. Significance of Q wave regression after transmural acute myocardial infarction. Am J Cardiol 1988;61(10):739-42. [Crossref]
  • 10. Yasuda M, Iida H, Itagane H, Tahara A, Toda I, Akioka K, et al. Significance of Q wave disappearance in the chronic phase following transmural acute myocardial infarction. Jpn Circ J 1990;54(12):1517-24. [Crossref]
  • 11. Ishikawa K, Shimizu M, Ohno M, Morishita M, Ogawa I, Hayashi T, et al. Clinical significance of abnormal Q wave disappearance in acute transmural myocardial infarction. Jpn Circ J 1991;55(3):213-20. [Crossref]
  • 12. Delewi R, Ijff G, van de Hoef TP, Hirsch A, Robbers LF, Nijveldt R, et al. Pathological Q waves in myocardial infarction in patients treated by primary PCI. JACC Cardiovasc Imaging 2013;6:324-31. [Crossref]
  • 13. Waks JW, Sabatine MS, Cannon CP, Morrow DA, Gibson CM, Wiviott SD, et al. Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: Observations from the CLARITY-TIMI 28 trial. Clin Cardiol 2014;37(3):160-6. [Crossref]
  • 14. McDonald MA, Fu Y, Zeymer U, Wagner G, Goodman SG, Ross A, et al. Adverse outcomes in fibrinolytic-based facilitated percutaneous coronary intervention: Insights from the ASSENT-4 PCI electrocardiographic substudy. Eur Heart J 2008;29(7):871-9. [Crossref]
  • 15. LaBounty T, Gurm HS, Goodman SG, Montalescot G, Lopez-Sendon J, Quill A, et al. Predictors and implications of Q waves in ST-elevation acute coronary syndromes. Am J Med 2009;122(2):144-51. [Crossref]
  • 16. Wong CK, Gao W, Raffel OC, French JK, Stewart RA, White HD. Initial Q waves accompanying ST-segment elevation at presentation of acute myocardial infarction and 30-day mortality in patients given streptokinase therapy: An analysis from HERO-2. Lancet 2006;367(9528):2061-7. [Crossref]
  • 17. Stone GW, Selker HP, Thiele H, Patel MR, Udelson JE, Ohman EM, et al. Relationship between infarct size and outcomes following primary PCI: Patient-level analysis from 10 randomized trials. J Am Coll Cardiol 2016;67(14):1674-83. [Crossref]
  • 18. Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2018;39(2):119-77. [Crossref]

Regression of Q Waves and Clinical Outcomes After Primary Percutaneous Coronary Intervention in St Elevation Myocardial Infarction

Yıl 2022, Cilt: 25 Sayı: 2, 127 - 131, 20.08.2022

Öz

Introduction: Pathological Q waves are correlated with infarct size, and Q wave regression is associated with left ventricular ejection fraction improvement. There are limited data regarding the association between Q wave regression and clinical outcomes. Our main objective was to assess the association of pathological Q wave evolution after reperfusion with clinical outcomes after ST-elevation myocardial infarction (STEMI).

Patients and Methods: Standard 12-lead electrocardiograms (ECGs) were recorded in 1553 patients, who presented to our hospital with chest pain and underwent primary percutaneous coronary intervention (p-PCI) with the diagnosis of STEMI and were retrospectively analyzed. ECGs were recorded before and 90 min after PCI, as well as at hospitalization discharge and 12 months of follow-up. The study population was divided into three groups as the Q wave regression group, the Q wave persistent group, and the non-Q wave MI group.

Results: There were 502 (32%) patients with persistent Q waves (PQ group), 509 (33%) patients with Q wave regression (RQ group), and 542 (35%) patients with non-Q wave MI (NQ group). The degree of LVEF was significantly greater in the RQ group and NQ group than in the PQ group [(47.5 ± 10.1 vs. 49.2 ± 9.9) vs. 43.3 ± 10.5 respectively, p< 0.01]. One-year mortality was significantly greater in the PQ group compared to the RQ and NQ groups [19 (3.78%) vs. 11 (2.16%) vs. 6 (1.1%) respectively, p< 0.01].

Conclusion: In a population of STEMI patients, persistent Q waves defined according to the classic ECG criteria after reperfusion were associated with high one-year mortality, and low LVEF, while Q wave regression was associated with significantly lower risk of events.

Kaynakça

  • 1. Pahlm O, Wagner GS. QRS, ST and T changes of acute transmural myocardial ischemia: Overview editorial. J Electrocardiol 2014;47(4):397-401. [Crossref]
  • 2. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD; Joint ESC/ACCF/AHA/WHF Task Force for Universal Definition of Myocardial Infarction; Third universal definition of myocardial infarction. J Am Coll Cardiol 2012;60(16):1581-98. [Crossref]
  • 3. Bateman TM, Czer LS, Gray RJ, Maddahi J, Raymond MJ, Geft IL, et al. Transient pathologic Q waves during acute ischemic events: An electrocardiographic correlate of stunned but viable myocardium. Am Heart J 1983;106(6):1421-6. [Crossref]
  • 4. Kochav JD, Okin PM, Wilson S, Afroz A, Renilla A, Weinsaft JW. Usefulness of Q wave area for threshold-based stratification of global left ventricular myocardial infarct size. Am J Cardiol 2013;112(2):174-80. [Crossref]
  • 5. Michael MA, El Masry H, Khan BR, Das MK. Electrocardiographic signs of remote myocardial infarction. Prog Cardiovasc Dis 2007;50(3):198-208. [Crossref]
  • 6. Antman EM, McCabe CH, Gurfinkel EP, Turpie AG, Bernink PJ, Salein D, et al. Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q wave myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) 11B trial. Circulation 1999;100(15):1593-601. [Crossref]
  • 7. Karakuş A, Uğuz B. Prognostic value of the Selvester QRS score for re-hospitalization in patients with ischemic heart failure. J Surg Med 2020;4(12):1165-8. [Crossref]
  • 8. Jaarsma W, Visser CA, van Eenige MJ, Roos JP. Left ventricular wall motion with and without Q wave disappearance after acute myocardial infarction. Am J Cardiol 1987;59(6):516-8. [Crossref]
  • 9. Coll S, Betriu A, de Flores T, Roig E, Sanz G, Mont L, et al. Significance of Q wave regression after transmural acute myocardial infarction. Am J Cardiol 1988;61(10):739-42. [Crossref]
  • 10. Yasuda M, Iida H, Itagane H, Tahara A, Toda I, Akioka K, et al. Significance of Q wave disappearance in the chronic phase following transmural acute myocardial infarction. Jpn Circ J 1990;54(12):1517-24. [Crossref]
  • 11. Ishikawa K, Shimizu M, Ohno M, Morishita M, Ogawa I, Hayashi T, et al. Clinical significance of abnormal Q wave disappearance in acute transmural myocardial infarction. Jpn Circ J 1991;55(3):213-20. [Crossref]
  • 12. Delewi R, Ijff G, van de Hoef TP, Hirsch A, Robbers LF, Nijveldt R, et al. Pathological Q waves in myocardial infarction in patients treated by primary PCI. JACC Cardiovasc Imaging 2013;6:324-31. [Crossref]
  • 13. Waks JW, Sabatine MS, Cannon CP, Morrow DA, Gibson CM, Wiviott SD, et al. Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: Observations from the CLARITY-TIMI 28 trial. Clin Cardiol 2014;37(3):160-6. [Crossref]
  • 14. McDonald MA, Fu Y, Zeymer U, Wagner G, Goodman SG, Ross A, et al. Adverse outcomes in fibrinolytic-based facilitated percutaneous coronary intervention: Insights from the ASSENT-4 PCI electrocardiographic substudy. Eur Heart J 2008;29(7):871-9. [Crossref]
  • 15. LaBounty T, Gurm HS, Goodman SG, Montalescot G, Lopez-Sendon J, Quill A, et al. Predictors and implications of Q waves in ST-elevation acute coronary syndromes. Am J Med 2009;122(2):144-51. [Crossref]
  • 16. Wong CK, Gao W, Raffel OC, French JK, Stewart RA, White HD. Initial Q waves accompanying ST-segment elevation at presentation of acute myocardial infarction and 30-day mortality in patients given streptokinase therapy: An analysis from HERO-2. Lancet 2006;367(9528):2061-7. [Crossref]
  • 17. Stone GW, Selker HP, Thiele H, Patel MR, Udelson JE, Ohman EM, et al. Relationship between infarct size and outcomes following primary PCI: Patient-level analysis from 10 randomized trials. J Am Coll Cardiol 2016;67(14):1674-83. [Crossref]
  • 18. Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2018;39(2):119-77. [Crossref]
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Orijinal Araştırmalar
Yazarlar

Zeki Şimşek 0000-0001-5594-420X

Sedat Kalkan Bu kişi benim 0000-0002-4202-2932

Regayip Zehir Bu kişi benim 0000-0003-2729-884X

Elnur Alizade Bu kişi benim 0000-0001-8688-406X

Yayımlanma Tarihi 20 Ağustos 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 25 Sayı: 2

Kaynak Göster

Vancouver Şimşek Z, Kalkan S, Zehir R, Alizade E. Regression of Q Waves and Clinical Outcomes After Primary Percutaneous Coronary Intervention in St Elevation Myocardial Infarction. Koşuyolu Heart Journal. 2022;25(2):127-31.