Araştırma Makalesi
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FİSTÜLOTOMİ VEYA SETON FONKSİYONELLİĞİ AZALTIR MI? RETROSPEKTİF KARŞILAŞTIRMA

Yıl 2026, Cilt: 7 Sayı: 1 , 1 - 6 , 28.04.2026
https://doi.org/10.52831/kjhs.1744101
https://izlik.org/JA46GG56RK

Öz

Amaç: Anal kanal ile perianal cilt arasında oluşan anormal traktlar olan anal fistüller sıklıkla cerrahi müdahale gerektirmektedir. Çalışmamızda düşük transsfinkterik anal fistül tanısı alan hastalarda fistülotomi veya seton uygulaması sonrası preoperatif ve postoperatif ağrı ile fonksiyonel bozukluk değerlendirildi.
Yöntem: Retrospektif bir kohort çalışmasıyla 1 Ocak 2022-1 Aralık 2024 tarihleri arasında Muğla Eğitim ve Araştırma Hastanesi’nde tedavi edilmiş hastalar incelendi. Önceden proktolojik cerrahi öyküsü olanlar, kompleks fistüller veya fonksiyon kaybına neden olabilecek eşlik eden hastalıkları bulunan hastalar dışlandı. Hastaların ağrı ve fonksiyonları, Visual Analog Skala (VAS) ve Dünya Sağlık Örgütü Yetiyitimi Değerlendirme Çizelgesi 2.0 (WHODAS 2.0) ile preoperatif, postoperatif 1. hafta ve 1. ayda değerlendirildi.
Bulgular: Altmış iki fistülotomi, 55 seton olmak üzere toplamda 117 hasta çalışmaya dahil edildi. VAS skoru 1. haftada fistülotomi grubunda anlamlı şekilde artarken, 1. ayda ise belirgin azaldı (p<0.001). Seton grubundaysa VAS skorunda belirgin bir değişiklik olmadı (p>0.05). Postoperatif birinci haftada ve birinci ayda değerlendirilen WHODAS 2.0 toplam skoru ve alt ölçeklerinden hareket, yaşam aktiviteleri, topluma katılma fistülotomi grubunda anlamlı şekilde arttı (p<0.05). Seton grubundaysa WHODAS 2.0 skoru 1. haftada anlamlı şekilde arttı (p<0.001).
Sonuç: Erken dönemde fistülotomi daha fazla ağrıya neden olsa da uzun vadede ağrı ve fonksiyon açısından daha iyi sonuçlar sağlamaktadır. Başlangıçta daha tolere edilebilir olan seton uygulaması ise kalıcı ağrı ve fonksiyon kaybı riski taşımaktadır. Cerrahi tercih yapılırken sadece anatomik iyileşme değil, hastaların yaşam kalitesi de dikkate alınmalıdır.

Kaynakça

  • Parks AG, Gordon PH, Hardcastle JD. A classification of fistula-in-ano. Br J Surg. 1976;63(1):1-12.
  • Ferrer-Márquez M, Espínola-Cortés N, Reina-Duarte A, Granero-Molina J, Fernández-Sola C, Hernández-Padilla JM. Design and psychometric evaluation of the quality of life in patients with anal fistula questionnaire. Dis Colon Rectum. 2017;60(10):1083-1091.
  • Yu Q, Zhi C, Jia L, Li H. Cutting seton versus decompression and drainage seton in the treatment of high complex anal fistula: a randomized controlled trial. Sci Rep. 2022;12(1):7838.
  • McCourtney JS, Finlay IG. Setons in the surgical management of fistula in ano. Br J Surg. 1995;82(4):448-452.
  • Sharma, P., Yan, E., Cui, A. et al. Prevalence of perioperative functional disability using WHODAS 2.0 and associated adverse outcomes in surgical populations: A systematic review and meta-analysis. Anaesth Crit Care Pain Med. 2026;45:1-10.
  • Ustun TB, Kostanjesek N, Chatterji S, Rehm J. Measuring health and disability: manual for who disability assessment schedule (‎WHODAS 2.0). World Health Organization; 2010.
  • Cline ME, Herman J, Shaw ER, Morton RD. Standardization of the visual analogue scale. Nurs Res. 1992;41(6):378-380.
  • Cianci P, Tartaglia N, Fersini A, Giambavicchio LL, Neri V, Ambrosi A. The Ligation of Intersphincteric Fistula Tract Technique: A Preliminary Experience. Ann Coloproctol. 2019;35(5):238-241.
  • Koizumi M, Matsuda A, Yamada T et al. A case report of anal fistula-associated mucinous adenocarcinoma developing 3 years after treatment of perianal abscess. Surg Case Rep. 2023;9(1):159.
  • Sahara R, Koizumi M, Morimoto K, Kubota I. Subcutaneous incision of the fistula tract and internal sphincterotomy (SIFT-IS): a novel surgical procedure for transsphincteric anal fistula. Colorectal Dis. 2022;24(12):1576-1583.
  • Suhardja TS, Lim JT, Duieb Z, Nguyen TC, Teoh WMK, Chouhan H. How to do a Fistula tract Laser Closure (FiLaC) for trans-sphincteric fistula-in-ano. ANZ J Surg. 2021;91(6):1292-1294.
  • Tahir M, Rahman J, Zubair T, Basit A. An Association of Mucinous Adenocarcinoma With Chronic Peri-Anal Fistula: A Brief Review of Pathophysiology of Rare Tumor. Cureus. 2020;12(6):1-9
  • Zhang Y, Li F, Zhao T, Cao F, Zheng Y, Li A. Treatment of Complex Anal Fistula by Video-Assisted Anal Fistula Treatment Combined with Anal Fistula Plug: A Single-Center Study. Surg Innov. 2021;28(6):688-694.
  • Zhang Y, Li F, Zhao T, Cao F, Zheng Y, Li A. Video-assisted anal fistula treatment combined with anal fistula plug for treatment of horseshoe anal fistula. J Int Med Res. 2021;49(1):1-15.
  • Ji L, Zhang Y, Xu L, Wei J, Weng L, Jiang J. Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies. Front Surg. 2021;7:586891.
  • Zhao Y, Xie W, Wu X et al. Anal fistulotomy with one-stage shaped skin grafting for intersphincter anal fistulas: study protocol on a multicentre randomised controlled trial. Trials. 2023;24(1):470.
  • Sileri, P., Franceschilli, L, et al. Minimally invasive approaches for anal fistula: an updated systematic review and meta-analysis. Colorectal Disease, 2023;25(7):1845-1857.
  • Durgun C, Tüzün A. The use of a loose seton as a definitive surgical treatment for anorectal abscesses and complex anal fistulas. Adv Clin Exp Med. 2023;32(10):1149-1157.
  • Schwandner O. Stem cell injection for complex anal fistula in Crohn's disease: A single-center experience. World J Gastroenterol. 2021;27(24):3643-3653.
  • Schwandner O, Roblin X. Emerging regenerative therapies in the management of complex anal fistulas. World J Gastroenterol. 2024;30(2), 233-245.
  • He Z, Du J, Wu K, et al. Formation rate of secondary anal fistula after incision and drainage of perianal Sepsis and analysis of risk factors. BMC Surg. 2020;20(1):94.
  • Huang B, Wang X, Zhou D, et al. Treating highly complex anal fistula with a new method of combined intraoperative endoanal ultrasonography (IOEAUS) and transanal opening of intersphincteric space (TROPIS). Wideochir Inne Tech Maloinwazyjne. 2021;16(4):697-703.

DOES FISTULOTOMY OR SETON REDUCE FUNCTIONALITY? A RETROSPECTIVE COMPARISON

Yıl 2026, Cilt: 7 Sayı: 1 , 1 - 6 , 28.04.2026
https://doi.org/10.52831/kjhs.1744101
https://izlik.org/JA46GG56RK

Öz

Objective: Anal fistulas, abnormal tracts that form between the anal canal and the perianal skin, frequently require surgical intervention. In our study, we evaluated preoperative and postoperative pain and functional impairment after fistulotomy or seton placement in patients diagnosed with low transsphincteric anal fistulas.
Method: A retrospective cohort study was conducted on patients treated at Muğla Training and Research Hospital between January 1, 2022, and December 1, 2024. Patients with a history of proctologic surgery, complex fistulas, or concomitant diseases that could cause functional loss were excluded. Patients' pain and function were assessed preoperatively at 1 week, and 1 month postoperatively using the Visual Analog Scale (VAS) and the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0).
Results: A total of 117 patients were included in the study: 62 fistulotomies and 55 setons. The VAS score increased significantly in the fistulotomy group at week 1 and decreased significantly at month 1 (p<0.001). There was no significant change in the VAS score in the seton group (p>0.05). The WHODAS 2.0 total score and its subscales, including mobility, activities of living, and community participation, assessed at 1 week and 1 month postoperatively, increased significantly in the fistulotomy group. (p<0.05). The WHODAS 2.0 score increased significantly in the seton group at week 1 (p<0.001).
Conclusion: Although fistulotomy causes more pain in the early period, it provides better long-term results in terms of pain and function. While initially more tolerable, seton placement carries the risk of permanent pain and loss of function. When making a surgical decision, not only anatomical improvement but also patient quality of life should be considered.

Etik Beyan

Ethics committee approval was received from Muğla Sıtkı Koçman University Medicine and Health Sciences Ethics Committee (Decision date: 22.12.2021, Protocol no: 210033, Decision no: 27)

Kaynakça

  • Parks AG, Gordon PH, Hardcastle JD. A classification of fistula-in-ano. Br J Surg. 1976;63(1):1-12.
  • Ferrer-Márquez M, Espínola-Cortés N, Reina-Duarte A, Granero-Molina J, Fernández-Sola C, Hernández-Padilla JM. Design and psychometric evaluation of the quality of life in patients with anal fistula questionnaire. Dis Colon Rectum. 2017;60(10):1083-1091.
  • Yu Q, Zhi C, Jia L, Li H. Cutting seton versus decompression and drainage seton in the treatment of high complex anal fistula: a randomized controlled trial. Sci Rep. 2022;12(1):7838.
  • McCourtney JS, Finlay IG. Setons in the surgical management of fistula in ano. Br J Surg. 1995;82(4):448-452.
  • Sharma, P., Yan, E., Cui, A. et al. Prevalence of perioperative functional disability using WHODAS 2.0 and associated adverse outcomes in surgical populations: A systematic review and meta-analysis. Anaesth Crit Care Pain Med. 2026;45:1-10.
  • Ustun TB, Kostanjesek N, Chatterji S, Rehm J. Measuring health and disability: manual for who disability assessment schedule (‎WHODAS 2.0). World Health Organization; 2010.
  • Cline ME, Herman J, Shaw ER, Morton RD. Standardization of the visual analogue scale. Nurs Res. 1992;41(6):378-380.
  • Cianci P, Tartaglia N, Fersini A, Giambavicchio LL, Neri V, Ambrosi A. The Ligation of Intersphincteric Fistula Tract Technique: A Preliminary Experience. Ann Coloproctol. 2019;35(5):238-241.
  • Koizumi M, Matsuda A, Yamada T et al. A case report of anal fistula-associated mucinous adenocarcinoma developing 3 years after treatment of perianal abscess. Surg Case Rep. 2023;9(1):159.
  • Sahara R, Koizumi M, Morimoto K, Kubota I. Subcutaneous incision of the fistula tract and internal sphincterotomy (SIFT-IS): a novel surgical procedure for transsphincteric anal fistula. Colorectal Dis. 2022;24(12):1576-1583.
  • Suhardja TS, Lim JT, Duieb Z, Nguyen TC, Teoh WMK, Chouhan H. How to do a Fistula tract Laser Closure (FiLaC) for trans-sphincteric fistula-in-ano. ANZ J Surg. 2021;91(6):1292-1294.
  • Tahir M, Rahman J, Zubair T, Basit A. An Association of Mucinous Adenocarcinoma With Chronic Peri-Anal Fistula: A Brief Review of Pathophysiology of Rare Tumor. Cureus. 2020;12(6):1-9
  • Zhang Y, Li F, Zhao T, Cao F, Zheng Y, Li A. Treatment of Complex Anal Fistula by Video-Assisted Anal Fistula Treatment Combined with Anal Fistula Plug: A Single-Center Study. Surg Innov. 2021;28(6):688-694.
  • Zhang Y, Li F, Zhao T, Cao F, Zheng Y, Li A. Video-assisted anal fistula treatment combined with anal fistula plug for treatment of horseshoe anal fistula. J Int Med Res. 2021;49(1):1-15.
  • Ji L, Zhang Y, Xu L, Wei J, Weng L, Jiang J. Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies. Front Surg. 2021;7:586891.
  • Zhao Y, Xie W, Wu X et al. Anal fistulotomy with one-stage shaped skin grafting for intersphincter anal fistulas: study protocol on a multicentre randomised controlled trial. Trials. 2023;24(1):470.
  • Sileri, P., Franceschilli, L, et al. Minimally invasive approaches for anal fistula: an updated systematic review and meta-analysis. Colorectal Disease, 2023;25(7):1845-1857.
  • Durgun C, Tüzün A. The use of a loose seton as a definitive surgical treatment for anorectal abscesses and complex anal fistulas. Adv Clin Exp Med. 2023;32(10):1149-1157.
  • Schwandner O. Stem cell injection for complex anal fistula in Crohn's disease: A single-center experience. World J Gastroenterol. 2021;27(24):3643-3653.
  • Schwandner O, Roblin X. Emerging regenerative therapies in the management of complex anal fistulas. World J Gastroenterol. 2024;30(2), 233-245.
  • He Z, Du J, Wu K, et al. Formation rate of secondary anal fistula after incision and drainage of perianal Sepsis and analysis of risk factors. BMC Surg. 2020;20(1):94.
  • Huang B, Wang X, Zhou D, et al. Treating highly complex anal fistula with a new method of combined intraoperative endoanal ultrasonography (IOEAUS) and transanal opening of intersphincteric space (TROPIS). Wideochir Inne Tech Maloinwazyjne. 2021;16(4):697-703.
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Gastroenteroloji ve Hepatoloji
Bölüm Araştırma Makalesi
Yazarlar

İpar Selin Demirci 0000-0001-9056-2696

Samet Şahin 0000-0003-0748-3458

Gönderilme Tarihi 16 Temmuz 2025
Kabul Tarihi 31 Ekim 2025
Yayımlanma Tarihi 28 Nisan 2026
DOI https://doi.org/10.52831/kjhs.1744101
IZ https://izlik.org/JA46GG56RK
Yayımlandığı Sayı Yıl 2026 Cilt: 7 Sayı: 1

Kaynak Göster

Vancouver 1.İpar Selin Demirci, Samet Şahin. DOES FISTULOTOMY OR SETON REDUCE FUNCTIONALITY? A RETROSPECTIVE COMPARISON. Karya J Health Sci. 01 Nisan 2026;7(1):1-6. doi:10.52831/kjhs.1744101