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THE VARIOUS THERAPEUTIC EFFECTS OF GINGER (ZINGIBER OFFICINALE ROSCOE) ON HUMAN HEALTH

Yıl 2021, , 55 - 60, 31.08.2021
https://doi.org/10.52831/kjhs.886448

Öz

Ginger is a yellowish root also called as spice which belongs to the zingiberaceae family and grown in various parts of the world, countries such as India, China, Nigeria, Sierra Leone, Indonesia, Bangladesh, Australia, Fiji, Jamaica and Nepal. It is a flowering plant with root, stem and leaves which can be consumed as fresh root, dried root, ground powder, pickle, ginger oil, ginger candy, ginger water or ginger tea. For thousands of years ginger has been used as a herbal medicine to prevent colds, digestive complaints, nausea and increase circulation in Ayurvedic, Indian and Chinese medicine. In addition to this, ginger is used as a medical plant in Roman, Greek and Ottoman medical history is shown in the records. Nowadays, there are many studies showing that it is important to prevent the nausea and vomiting due to chemotherapy, postoperative and in pregnancy; to use it in the treatment of colds, joint disease and asthma treatment; to reduce the risk of colorectal and prostate cancer, dysmenorrhea, diabetes and fat metabolism; and body composition in athletes improve exercise performance. When the effective components and chemical structure it contains are examined, two important phytochemicals, such as the volatile and non-volatile fatty acids show these effects of ginger. Although studies show positive effects of ginger on many health problems, more clinical research is needed to prove the most effective dose.

Kaynakça

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ZENCEFİL’İN (ZINGIBER OFFICINALE ROSCOE) İNSAN SAĞLIĞI ÜZERİNE ÇEŞİTLİ TERAPÖTİK ETKİLERİ

Yıl 2021, , 55 - 60, 31.08.2021
https://doi.org/10.52831/kjhs.886448

Öz

Zencefil (zingiber officinale roscoe), çoğunlukla Hindistan, Çin, Nijerya, Sierra Leone, Endonezya, Bangladeş, Avustralya, Fiji, Jamaika ve Nepal gibi ülkelerden gelen ve dünyanın çeşitli yerlerinde yetiştirilen zencefilgiller (zingiberaceace) ailesinden olan, baharat olarak da anılan yumru köklü sarımtırak bir bitkidir. Kök, gövde ve yaprakları olan bu bitki; taze kök, kuru kök, öğütülmüş toz, turşu, zencefil yağı, zencefil şekerlemesi, zencefilli su veya zencefil çayı olarak tüketilebilmektedir. Ayurvedik, Hint ve Çin tıbbında, soğuk algınlığını, sindirim şikâyetlerini, mide bulantısını önlemek ve dolaşımı arttırmak için bitkisel ilaç olarak binlerce yıldır kullanılmış ve Roma, Yunan ve Osmanlı tıp tarihi kayıtlarında tıbbi bir bitki olarak kullanıldığı gösterilmiştir. Günümüzde kemoterapi kaynaklı, ameliyat sonrası ve hamilelikteki bulantı ve kusmayı önlemede; soğuk algınlığı tedavisinde, eklem hastalığı ve astım tedavisinde, kolorektal ve prostat kanseri riskini azaltmada, dismenore, diyabet ve yağ metabolizması üzerine etkisinin olduğu, vücut kompozisyonunu ve egzersiz performansını arttırdığını gösteren birçok çalışma vardır. İçerdiği biyoaktif bileşenleri ve kimyasal yapısı incelendiğinde yapısında bulunan uçucu ve uçucu olmayan yağ asitleri gibi iki önemli fitokimyasal etkenler zencefilin etkilerini ortaya koymaktadır. Çalışmalarda, zencefilin birçok sağlık sorunu üzerine olumlu etkilerinin görülmesine rağmen; en etkili dozunun kanıtlanması için daha fazla klinik araştırmaya ihtiyaç duyulmaktadır.

Kaynakça

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  • 33. Borrelli F, Capasso R, Aviello G, et al. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Am Coll Obstet Gynecol. 2005;105(4):849-856.
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  • 35. Viljoen E, Visser J, Koen N, Musakiwa A. A Systematic review of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Nutr J. 2014;13(20):1-14.
  • 35. Viljoen E, Visser J, Koen N, Musakiwa A. A Systematic review of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Nutr J. 2014;13(20):1-14.
  • 36. Thomson M, Corbin R, Leung L. Effects of ginger for nausea and vomiting in early pregnancy: A meta-analysis. J Am Board Fam Med. 2014;27(1):115-122.
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  • 37. White B. Ginger: An overview. Am Acad Fam Physicians. 2007;75(11):1689-1691.
  • 38. Arslan M, Özdemir L. Kemoterapiye bağlı gelişen bulantı-kusmanın yönetiminde kullanılan tamamlayıcı tedavi yöntemleri. Türk Onkol Derg. 2015;30(2):82-89.
  • 38. Arslan M, Özdemir L. Kemoterapiye bağlı gelişen bulantı-kusmanın yönetiminde kullanılan tamamlayıcı tedavi yöntemleri. Türk Onkol Derg. 2015;30(2):82-89.
  • 39. Danwilai K, Konmun J, Sripanidkulchai BO, et al. Antioxidant activity of ginger extract as a daily supplement in cancer patients receiving adjuvant chemotherapy: A pilot study. Cancer Manag Res. 2017;9:11-18.
  • 39. Danwilai K, Konmun J, Sripanidkulchai BO, et al. Antioxidant activity of ginger extract as a daily supplement in cancer patients receiving adjuvant chemotherapy: A pilot study. Cancer Manag Res. 2017;9:11-18.
  • 40. Seidi J, Ebnerasooli S, Shahsawari S, et al. The influence of oral ginger before operation on nausea and vomiting after cataract sur-gery under general anesthesia: A double-blind placebo-controlled randomized clinical trial. Electron Physician. 2017;9(1):3508-3514.
  • 40. Seidi J, Ebnerasooli S, Shahsawari S, et al. The influence of oral ginger before operation on nausea and vomiting after cataract sur-gery under general anesthesia: A double-blind placebo-controlled randomized clinical trial. Electron Physician. 2017;9(1):3508-3514.
  • 41. Yadav S, Sharma K, Alam MA. Ginger medicinal uses and benefits. Eur J Pharm Med Res. 2016;3(7):127-135.
  • 41. Yadav S, Sharma K, Alam MA. Ginger medicinal uses and benefits. Eur J Pharm Med Res. 2016;3(7):127-135.
  • 42. Roy HJ, Lundy S, Eriksen C, Kalicki B. Ginger a potent root. Penningt Nutr Ser. 2007;(6):1-4.
  • 42. Roy HJ, Lundy S, Eriksen C, Kalicki B. Ginger a potent root. Penningt Nutr Ser. 2007;(6):1-4.
  • 43. Heimes K, Feistel B, Verspohl EJ. Impact of the 5-HT3 receptor channel system for insulin secretion and interaction of ginger extracts. Eur J Pharmacol. 2009;624:58-65.
  • 43. Heimes K, Feistel B, Verspohl EJ. Impact of the 5-HT3 receptor channel system for insulin secretion and interaction of ginger extracts. Eur J Pharmacol. 2009;624:58-65.
  • 44. Chakraborty D, Mukherjee A, Sikdar S, et al. [6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice. Toxicol Lett. 2012;210(1):34-43.
  • 44. Chakraborty D, Mukherjee A, Sikdar S, et al. [6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice. Toxicol Lett. 2012;210(1):34-43.
  • 45. Aryaeian N, Tavakkoli H. Ginger and its effects on inflammatory diseases. Adv Food Technol Nutr Sci Open J. 2015;1(4):97-101.
  • 45. Aryaeian N, Tavakkoli H. Ginger and its effects on inflammatory diseases. Adv Food Technol Nutr Sci Open J. 2015;1(4):97-101.
  • 46. Mashhadi NS, Ghiasvand R, Hariri M, et al. Effect of ginger and cinnamon intake on oxidative stress and exercise performance and body composition in Iranian female athletes. Int J Prev Med. 2013;4(1):31-35.
  • 46. Mashhadi NS, Ghiasvand R, Hariri M, et al. Effect of ginger and cinnamon intake on oxidative stress and exercise performance and body composition in Iranian female athletes. Int J Prev Med. 2013;4(1):31-35.
  • 47. Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001;44(11):2531-2538.
  • 47. Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001;44(11):2531-2538.
  • 48. Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (zingiber officinale roscoe): A review of recent research. Clin Pharm. 2008;46:409-420.
  • 48. Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (zingiber officinale roscoe): A review of recent research. Clin Pharm. 2008;46:409-420.
  • 49. J Jung HW, Yoon CH, Park KM, Han HS, Park YK. Hexane fraction of zingiberis rhizoma crudus extract inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated BV2 microglial cells via the NF-kappaB pathway. Food Chem Toxicol. 2009;47(6):1190-1197.
  • 49. J Jung HW, Yoon CH, Park KM, Han HS, Park YK. Hexane fraction of zingiberis rhizoma crudus extract inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated BV2 microglial cells via the NF-kappaB pathway. Food Chem Toxicol. 2009;47(6):1190-1197.
  • 50. Leach MJ, Kumar S. The clinical effectiveness of ginger (zingiber officinale) in adults with osteoarthritis. Int J Evid Based Healthc. 2008;6(3):311-320.
  • 50. Leach MJ, Kumar S. The clinical effectiveness of ginger (zingiber officinale) in adults with osteoarthritis. Int J Evid Based Healthc. 2008;6(3):311-320.
  • 51. Townsend EA, Siviski ME, Zhang Y, Xu C, Hoonjan B, Emala CW. Effects of ginger and its constituents on airway smooth muscle relaxation and calcium regulation. Am J Respir Cell Mol Biol. 2013;48(2):157-163.
  • 51. Townsend EA, Siviski ME, Zhang Y, Xu C, Hoonjan B, Emala CW. Effects of ginger and its constituents on airway smooth muscle relaxation and calcium regulation. Am J Respir Cell Mol Biol. 2013;48(2):157-163.
  • 52. Chen CX, Barrett B, Kwekkeboom KL. Efficacy of oral ginger (zingiber officinale) for dysmenorrhea: a systematic review and meta-analysis. Evidence-based Complement Altern Med. 2016. 53. Ewnetu Y, Lemma W, Birhane N. Synergetic antimicrobial effects of mixtures of Ethiopian honeys and ginger powder extracts on standard and resistant clinical bacteria isolates. Evidence-based Complement Altern Med. 2014;2014:17-19.
  • 52. Chen CX, Barrett B, Kwekkeboom KL. Efficacy of oral ginger (zingiber officinale) for dysmenorrhea: a systematic review and meta-analysis. Evidence-based Complement Altern Med. 2016. 53. Ewnetu Y, Lemma W, Birhane N. Synergetic antimicrobial effects of mixtures of Ethiopian honeys and ginger powder extracts on standard and resistant clinical bacteria isolates. Evidence-based Complement Altern Med. 2014;2014:17-19.
  • 54. Almotayri A, Jois M, Radcliffe J, Munasinghe M, Thomas J. The effects of red chilli, black pepper, turmeric, and ginger on body weight-A systematic review. Nutr Metabol. 2020;(19):1-8.
  • 54. Almotayri A, Jois M, Radcliffe J, Munasinghe M, Thomas J. The effects of red chilli, black pepper, turmeric, and ginger on body weight-A systematic review. Nutr Metabol. 2020;(19):1-8.
  • 55. Attari VE, Mahluji S, Jafarabadi MA, Ostadrahimi A. Effects of supplementation with ginger (zingiber officinale roscoe) on serum glucose, lipid profile and oxidative stress in obese women: A randomized, placebo-controlled clinical trial. Pharm Sci. 2015;21(4):184-191.
  • 55. Attari VE, Mahluji S, Jafarabadi MA, Ostadrahimi A. Effects of supplementation with ginger (zingiber officinale roscoe) on serum glucose, lipid profile and oxidative stress in obese women: A randomized, placebo-controlled clinical trial. Pharm Sci. 2015;21(4):184-191.
  • 56. Sang S, Snook HD, Tareq FS, Fasina Y. Precision research on ginger: the type of ginger matters. J Agric Food Chem. 2020;68(32):8517-8523.
  • 56. Sang S, Snook HD, Tareq FS, Fasina Y. Precision research on ginger: the type of ginger matters. J Agric Food Chem. 2020;68(32):8517-8523.
  • 57. Chang JS, Wang KC, Yeh CF, Shieh DE, Chiang LC. Fresh ginger (zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. J Ethnopharmacol. 2013;145(1):146-151.
  • 57. Chang JS, Wang KC, Yeh CF, Shieh DE, Chiang LC. Fresh ginger (zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. J Ethnopharmacol. 2013;145(1):146-151.
  • 58. Stanisiere J, Mousset PY, Lafay S. How safe is ginger rhizome for decreasing nausea and vomiting in women during early pregnancy? Foods. 2018;7(50):1-29.
  • 58. Stanisiere J, Mousset PY, Lafay S. How safe is ginger rhizome for decreasing nausea and vomiting in women during early pregnancy? Foods. 2018;7(50):1-29.
  • 59. Chrubasik S, Pittler MH, Eberhart L, et al. Addendum to a recent systematic review on ginger [multiple letters]. Forsch Komplementarmed Klass Naturheilkd. 2005;46:168-169.
  • 59. Chrubasik S, Pittler MH, Eberhart L, et al. Addendum to a recent systematic review on ginger [multiple letters]. Forsch Komplementarmed Klass Naturheilkd. 2005;46:168-169.
Toplam 116 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Derlemeler
Yazarlar

Damla Zeynep Bayraktar 0000-0001-6606-7206

Yayımlanma Tarihi 31 Ağustos 2021
Gönderilme Tarihi 25 Şubat 2021
Yayımlandığı Sayı Yıl 2021

Kaynak Göster

Vancouver Bayraktar DZ. ZENCEFİL’İN (ZINGIBER OFFICINALE ROSCOE) İNSAN SAĞLIĞI ÜZERİNE ÇEŞİTLİ TERAPÖTİK ETKİLERİ. Karya J Health Sci. 2021;2(2):55-60.